Outputs (89)

Monte Carlo simulations and phantom modeling for spatial frequency domain imaging of surgical wound monitoring (2023)
Journal Article

Postoperative surgical wound infection is a serious problem around the globe, including in countries with advanced healthcare systems, and a method for early detection of infection is urgently required. We explore spatial frequency domain imaging (SF... Read More about Monte Carlo simulations and phantom modeling for spatial frequency domain imaging of surgical wound monitoring.

Bullseye Analysis: A Fluorescence Microscopy Technique to Detect Local Changes in Intracellular Reactive Oxygen Species (ROS) Production (2022)
Journal Article

Reactive oxygen species (ROS) are naturally produced compounds that play important roles in cell signaling, gene regulation, and biological defense, including involvement in the oxidative burst that is central to the anti-microbial actions of macroph... Read More about Bullseye Analysis: A Fluorescence Microscopy Technique to Detect Local Changes in Intracellular Reactive Oxygen Species (ROS) Production.

Integrated fiber optic spectrally resolved downwelling irradiance sensor for pushbroom spectrometers (2022)
Journal Article

We present an integrated fiber optic spectrally resolved downwelling irradiance sensor for pushbroom hyperspectral imagers. The system comprises of a cosine corrector and custom fiber patch cables, collecting the ambient light in a large solid angle... Read More about Integrated fiber optic spectrally resolved downwelling irradiance sensor for pushbroom spectrometers.

Spectral index selection method for remote moisture sensing under challenging illumination conditions (2022)
Journal Article

Remote sensing using passive solar illumination in the Short-Wave Infrared spectrum is exposed to strong intensity variation in the spectral bands due to atmospheric changing conditions and spectral absorption. More robust spectral analysis methods,... Read More about Spectral index selection method for remote moisture sensing under challenging illumination conditions.

Feature issue introduction: applications of adaptive optics (2021)
Journal Article

This feature issue of Optics Express follows the 2020 Imaging and Applied Optics Congress and comprises of articles on the development and use of adaptive optics across the broad range of domains in which the technique has been applied - including at... Read More about Feature issue introduction: applications of adaptive optics.

Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution (2021)
Journal Article

The use of optical techniques to interrogate wide ranging samples from semiconductors to biological tissue for rapid analysis and diagnostics has gained wide adoption over the past decades. The desire to collect ever more spatially, spectrally and te... Read More about Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution.

Full Spectrum Fluorescence Lifetime Imaging with 0.5 nm Spectral and 50 ps Temporal Resolution (2021)
Journal Article

Freeform based hYperspectral imager for MOisture Sensing (FYMOS) (2021)
Journal Article

We present FYMOS, an all-aluminum, robust, light weight, freeform based, near infrared hYperspectral imager for MOisture Sensing. FYMOS was designed and built to remotely measure moisture content using spectral features from 0.7-1.7µm integrating an... Read More about Freeform based hYperspectral imager for MOisture Sensing (FYMOS).

A history of high-power laser research and development in the United Kingdom (2021)
Journal Article

The first demonstration of laser action in ruby was made in 1960 by T. H. Maiman of Hughes Research Laboratories, USA. Many laboratories worldwide began the search for lasers using different materials, operating at different wavelengths. In the UK, a... Read More about A history of high-power laser research and development in the United Kingdom.

LightBox: a multiwell plate illumination system for photoactive molecule characterization (2021)
Journal Article

Multiwell plates (MWPs) are the workhorses of the life sciences. However, biophotonics research with MWPs is limited, in part due to the lack of equipment suitable for photo‐irradiation of photoactive molecules in a MWP‐suitable, high‐throughput mann... Read More about LightBox: a multiwell plate illumination system for photoactive molecule characterization.

Early stage dental caries detection using near infrared spatial frequency domain imaging (2021)
Journal Article

Early stage dental caries can be remineralized without the need for “drill-and-fill” treatments that are more invasive and less permanent. However, early stage caries lesions typically present as a white spot on a white background, resulting in many... Read More about Early stage dental caries detection using near infrared spatial frequency domain imaging.

Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes and strain-dependent differences in epithelial cell organization (2020)
Journal Article

Organ and tissue development are highly coordinated processes; lens growth and functional integration into the eye (emmetropia) is a robust example. An epithelial monolayer covers the anterior hemisphere of the lens, and its organization is the key t... Read More about Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes and strain-dependent differences in epithelial cell organization.

Cellular localisation of structurally diverse diphenylacetylene fluorophores (2020)
Journal Article

Fluorescent probes are increasingly used as reporter molecules in a wide variety of biophysical experiments, but when designing new compounds it can often be difficult to anticipate the effect that changing chemical structure can have on cellular loc... Read More about Cellular localisation of structurally diverse diphenylacetylene fluorophores.

Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events (2019)
Journal Article

Rapid imaging of multiple focal planes without sample movement may be achieved through remote refocusing, where imaging is carried out in a plane conjugate to the sample plane. The technique is ideally suited to studying the endothelial and smooth mu... Read More about Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events.

A CMOS SPAD Line Sensor With Per-Pixel Histogramming TDC for Time-Resolved Multispectral Imaging (2019)
Journal Article

A 512 × 16 single photon avalanche diode (SPAD)-based line sensor is designed in a 0.13- μm CMOS image sensor technology for time-resolved multispectral beam scanned imaging. The sensor has 23.78- μm pixel pitch and incorporates one SPAD array with 4... Read More about A CMOS SPAD Line Sensor With Per-Pixel Histogramming TDC for Time-Resolved Multispectral Imaging.

Scattering of spoof surface plasmon polaritons in defect-rich THz waveguides (2019)
Journal Article

We report on the first observation of ‘Spoof’ Surface Plasmon Polariton (SPP) scattering from surface defects on metal-coated 3D printed, corrugated THz waveguiding surfaces. Surface defects, a result of the printing process, are shown to assist the... Read More about Scattering of spoof surface plasmon polaritons in defect-rich THz waveguides.

Photoactivated cell-killing involving a low molecular weight, donor-acceptor diphenylacetylene (2019)
Journal Article

Photoactivation of photosensitisers can be utilised to elicit the production of ROS, for potential therapeutic applications, including the destruction of diseased tissues and tumours. A novel class of photosensitiser, exemplified by DC324, has been d... Read More about Photoactivated cell-killing involving a low molecular weight, donor-acceptor diphenylacetylene.

VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology (2019)
Journal Article

Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of th... Read More about VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology.

High-speed dual color fluorescence lifetime endomicroscopy for highly-multiplexed pulmonary diagnostic applications and detection of labeled bacteria (2018)
Journal Article

We present a dual-color laser scanning endomicroscope capable of fluorescence lifetime endomicroscopy at one frame per second (FPS). The scanning system uses a coherent imaging fiber with 30,000 cores. High-speed lifetime imaging is achieved by distr... Read More about High-speed dual color fluorescence lifetime endomicroscopy for highly-multiplexed pulmonary diagnostic applications and detection of labeled bacteria.

Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling (2018)
Journal Article

Endothelial cells are reported to be glycolytic and to minimally rely on mitochondria for ATP generation. Rather than providing energy, mitochondria in endothelial cells may act as signaling organelles that control cytosolic Ca2+ signaling or modify... Read More about Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling.

Tandem fluorescence and Raman (fluoRaman) characterisation of a novel photosensitiser in colorectal cancer cell line SW480 (2018)
Journal Article

The development of new imaging tools, molecules and modalities is crucial to understanding biological processes and the localised cellular impact of bioactive compounds. A small molecule photosensitiser, DC473, has been designed to be both highly flu... Read More about Tandem fluorescence and Raman (fluoRaman) characterisation of a novel photosensitiser in colorectal cancer cell line SW480.

Effects of maternal anxiety and depression on fetal neuro-development (2018)
Journal Article

Background: Fetal development is affected by maternal mental health with research indicating that maternal anxiety and depression are co-morbid; nevertheless differential effects on the fetus have been found. This study examines, prenatally, effects... Read More about Effects of maternal anxiety and depression on fetal neuro-development.

The light-sheet microscopy revolution (2018)
Journal Article

This paper reviews the rapid advances that have been made in one form of optical biological imaging in the last decade, namely that of light-sheet microscopy. Although the concept was originally presented over one hundred years ago, it was a methodol... Read More about The light-sheet microscopy revolution.

Non-invasive in vivo quantification of the developing optical properties and graded index of the embryonic eye lens using SPIM (2018)
Journal Article

Graded refractive index lenses are inherent to advanced visual systems in animals. By understanding their formation and local optical properties, significant potential for improved ocular healthcare may be realized. We report a novel technique measur... Read More about Non-invasive in vivo quantification of the developing optical properties and graded index of the embryonic eye lens using SPIM.

Design, manufacture, and evaluation of prototype telescope windows for use in low-vision aids (2017)
Presentation / Conference Contribution

Pixellated Optics, a class of optical devices which preserve phase front continuity only over small sub areas of the device, allow for a range of uses that would not otherwise be possible. One potential use is as Low Vision Aids (LVAs), where they ar... Read More about Design, manufacture, and evaluation of prototype telescope windows for use in low-vision aids.

Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish (2017)
Journal Article

The ability to kill individual or groups of cells in vivo is important for studying cellular processes and their physiological function. Cell-specific genetically encoded photosensitizing proteins, such as KillerRed, permit spatiotemporal optogenetic... Read More about Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish.

Towards a high-throughput real-time confocal microfluidic system for monitoring absorbance spectra in mixed-phase chemical reactions (2017)
Journal Article

In this work, we present a compact, real-time absorbance spectroscopy instrument, designed with a particular focus on taking spectroscopic readings in a microfluidic channel environment and selectively analysing an active volume in this channel by ad... Read More about Towards a high-throughput real-time confocal microfluidic system for monitoring absorbance spectra in mixed-phase chemical reactions.

Advancing Age Decreases Pressure-Sensitive Modulation of Calcium Signaling in the Endothelium of Intact and Pressurized Arteries (2017)
Journal Article

Aging is the summation of many subtle changes which result in altered cardiovascular function. Impaired endothelial function underlies several of these changes and precipitates plaque development in larger arteries. The endothelium transduces chemica... Read More about Advancing Age Decreases Pressure-Sensitive Modulation of Calcium Signaling in the Endothelium of Intact and Pressurized Arteries.

Shear banding in large amplitude oscillatory shear (LAOStrain and LAOStress) of polymers and wormlike micelles (2016)
Journal Article

We investigate theoretically shear banding in large amplitude oscillatory shear (LAOS) of polymers and wormlike micelles. In LAOStrain we find banding at low frequencies and sufficiently high strain rate amplitudes in fluids for which the underlying... Read More about Shear banding in large amplitude oscillatory shear (LAOStrain and LAOStress) of polymers and wormlike micelles.

Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue (2016)
Journal Article

We demonstrate a fast two-color widefield fluorescence microendoscopy system capable of simultaneously detecting several disease targets in intact human ex vivo lung tissue. We characterize the system for light throughput from the excitation light em... Read More about Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue.

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle (2016)
Journal Article

Mitochondrial function, motility and architecture are each central to cell function. Age-associated mitochondrial dysfunction may contribute to vascular disease. However, mitochondrial changes in ageing remain ill-defined because of the challenges of... Read More about Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle.

Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium (2016)
Journal Article

Agonist-mediated signaling by the endothelium controls virtually all vascular functions. Because of the large diversity of agonists, each with varying concentrations, background noise often obscures individual cellular signals. How the endothelium di... Read More about Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium.

Flicker-assisted localization microscopy reveals altered mitochondrial architecture in hypertension (2015)
Journal Article

Mitochondrial morphology is central to normal physiology and disease development. However, in many live cells and tissues, complex mitochondrial structures exist and morphology has been difficult to quantify. We have measured the shape of electricall... Read More about Flicker-assisted localization microscopy reveals altered mitochondrial architecture in hypertension.

Pressure-dependent regulation of Ca2+ signalling in the vascular endothelium (2015)
Journal Article

The endothelium is an interconnected network upon which haemodynamic mechanical forces act to control vascular tone and remodelling in disease. Ca2+ signalling is central to the endothelium's mechanotransduction and networked activity. However, chall... Read More about Pressure-dependent regulation of Ca2+ signalling in the vascular endothelium.

A dimensionless ordered pull-through model of the mammalian lens epithelium evidences scaling across species and explains the age-dependent changes in cell density in the human lens (2015)
Journal Article

We present a mathematical (ordered pull-through; OPT) model of the cell-density profile for the mammalian lens epithelium together with new experimental data. The model is based upon dimensionless parameters, an important criterion for inter-species... Read More about A dimensionless ordered pull-through model of the mammalian lens epithelium evidences scaling across species and explains the age-dependent changes in cell density in the human lens.

Realtime wavefront sensing in a SPIM microscope, and active aberration tracking (2015)
Presentation / Conference Contribution

Adaptive optics (AO) can potentially allow high resolution imaging deep inside living tissue, mitigating against the loss of resolution due to aberrations caused by overlying tissue. Closed-loop AO correction is particularly attractive for moving tis... Read More about Realtime wavefront sensing in a SPIM microscope, and active aberration tracking.

Quantitative High Dynamic Range Beam Proling for Fluorescence Microscopy (2014)
Journal Article

Modern developmental biology relies on optically-sectioning uorescence microscope techniques to produce non-destructive in-vivo images of developing specimens at high resolution in three dimensions. As optimal performance of these techniques is relia... Read More about Quantitative High Dynamic Range Beam Proling for Fluorescence Microscopy.

Enamel erosion and prevention efficacy characterized by confocal laser scanning microscope (2014)
Journal Article

The aim of this study was to evaluate the erosion-inhibiting effect of two toothpastes on the development of erosion-like lesions, by a confocal laser scanning microscope (CLSM). Forty human enamel blocks were divided into five groups (n = 8), in acc... Read More about Enamel erosion and prevention efficacy characterized by confocal laser scanning microscope.

Combining optical trapping in a microfluidic channel with simultaneous micro-Raman spectroscopy and motion detection (2014)
Presentation / Conference Contribution

Since their invention by Ashkin optical tweezers have demonstrated their ability and versatility as a non-invasive tool for micromanipulation. One of the most useful additions to the basic optical tweezers system is micro-Raman spectroscopy, which pe... Read More about Combining optical trapping in a microfluidic channel with simultaneous micro-Raman spectroscopy and motion detection.

Investigating the micro-rheology of the vitreous humor using an optically trapped local probe (2014)
Journal Article

We demonstrate that an optically trapped silica bead can be used as a local probe to measure the micro-rheology of the vitreous humor. The Brownian motion of the bead was observed using a fast camera and the micro-rheology determined by analysis of t... Read More about Investigating the micro-rheology of the vitreous humor using an optically trapped local probe.

AO modal optimization in a live, beating zebrafish heart (2013)
Presentation / Conference Contribution

We report on the combinated use of heart synchronization and wavefront sensorless modal AO to enable significant improvement in image quality of a live transgenic zebrafish embryo heart, imaged with a light sheet microscope.

Single Cell and Subcellular Measurements of Intracellular Ca2+ Concentration (2013)
Book Chapter

Increases in bulk average cytoplasmic Ca2+ concentration ([Ca2+]c) are derived from the combined activities of many Ca2+ channels. Near (

Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair (2013)
Journal Article

Background: While the adult zebrafish (Danio rerio) heart demonstrates a remarkable capacity for self-renewal following apical resection little is known about the response to injury in the embryonic heart. Methods: Injury to the beating zebrafish emb... Read More about Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair.

From Structure to Function: Mitochondrial Morphology, Motion and Shaping in Vascular Smooth Muscle (2013)
Journal Article

The diversity of mitochondrial arrangements, which arise from the organelle being static or moving, or fusing and dividing in a dynamically reshaping network, is only beginning to be appreciated. While significant progress has been made in understand... Read More about From Structure to Function: Mitochondrial Morphology, Motion and Shaping in Vascular Smooth Muscle.

Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy (2013)
Journal Article

We report on a closed loop widefield adaptive optics, optical microscopy system in which the feedback signal is provided by backscattered light from the sample acting as a guide star. The improvement in imaging performance is compared to an adaptive... Read More about Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy.

Light sheet adaptive optics microscope for 3D live imaging (2013)
Presentation / Conference Contribution

We report on the incorporation of adaptive optics (AO) into the imaging arm of a selective plane illumination microscope (SPIM). SPIM has recently emerged as an important tool for life science research due to its ability to deliver high-speed, optica... Read More about Light sheet adaptive optics microscope for 3D live imaging.

Adaptive optical methods for in vivo imaging in developing Zebra fish (2012)
Presentation / Conference Contribution

The humble Zebra fish is rapidly establishing itself as the model of choice for a wide range of biological investigations, in particular at the developing embryo stage. Single Plane Illumination Microscopy (SPIM) has already been shown to be a very p... Read More about Adaptive optical methods for in vivo imaging in developing Zebra fish.

3D adaptive optics in a light sheet microscope (2012)
Journal Article

We report on a single plane illumination microscope (SPIM) incorporating adaptive optics in the imaging arm. We show how aberrations can occur from the sample mounting tube and quantify the aberrations both experimentally and computationally. A wavef... Read More about 3D adaptive optics in a light sheet microscope.

Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging. (2012)
Journal Article

In this paper we report the design, testing and use of a scannerless probe specifically for minimally invasive imaging of deep tissue in vivo with an epi-fluorescence modality. The probe images a 500 μm diameter field of view through a 710 μm outer d... Read More about Micro-endoscope for in vivo widefield high spatial resolution fluorescent imaging..

Closed loop adaptive optics with a laser guide star for biological light microscopy (2012)
Presentation / Conference Contribution

We report on the development of a widefield microscope that achieves adaptive optics correction through the use of a wavefront sensor observing an artificial laser guide star induced within the sample. By generating this guide star at arbitrary posit... Read More about Closed loop adaptive optics with a laser guide star for biological light microscopy.

Wide field adaptive optics microscopy using both closed loop correction and image sharpness optimization (2011)
Presentation / Conference Contribution

We report on results from a wide field microscope fitted with adaptive optics. We describe results based on both image optimization (wavefront sensorless adaptive optics) and full closed loop correction.

Real-time optical gating for three-dimensional beating heart imaging. (2011)
Journal Article

Impact of wavefront distortion and scattering on 2-photon microscopy in mammalian brain tissue. (2011)
Journal Article

Two-photon (2P) microscopy is widely used in neuroscience, but the optical properties of brain tissue are poorly understood. We have investigated the effect of brain tissue on the 2P point spread function (PSF2P) by imaging fluorescent beads through... Read More about Impact of wavefront distortion and scattering on 2-photon microscopy in mammalian brain tissue..

Improved method for kinetic studies in microreactors using flow manipulation and noninvasive Raman spectrometry. (2011)
Journal Article

A novel method has been devised to derive kinetic information about reactions in microfluidic systems. Advantages have been demonstrated over conventional procedures for a Knoevenagel condensation reaction in terms of the time required to obtain the... Read More about Improved method for kinetic studies in microreactors using flow manipulation and noninvasive Raman spectrometry..

Multidepth, multiparticle tracking for active microrheology using a smart camera (2011)
Journal Article

The quantitative measurement of particle motion in optical tweezers is an important tool in the study of microrheology and can be used in a variety of scientific and industrial applications. Active microheology, in which the response of optically tra... Read More about Multidepth, multiparticle tracking for active microrheology using a smart camera.

Adaptive optics for wide-field microscopy (2011)
Presentation / Conference Contribution

We report on recent developments in the use of adaptive optics (AO) in wide-field microscopy to remove both system and sample induced aberrations. We describe progress on using both a full AO system and image optimization techniques (wavefront sensor... Read More about Adaptive optics for wide-field microscopy.

Heart synchronization for SPIM microscopy of living zebra fish (2011)
Presentation / Conference Contribution

We describe work on producing a selective plane illumination microscope for cardiac imaging in zebra fish embryos. The system has a novel synchronization system for imaging oscillating structures (e.g. the heart) and will have adaptive optics for ima... Read More about Heart synchronization for SPIM microscopy of living zebra fish.

A miniaturised integrated biophotonic point-of care genotyping system. (2010)
Journal Article

Non-invasive analysis in micro-reactors using Raman spectrometry with a specially designed probe. (2010)
Journal Article

Two-photon fluorescence excitation microscopy to assess transscleral diffusional pathways in an isolated perfused bovine eye model. (2010)
Journal Article

Development of a low-cost confocal instrument to measure the axial dimensions of components in the anterior section of the eye (2010)
Journal Article

Searched-based active optic systems for aberration correction in time-independent applications. (2010)
Journal Article

A demonstration of the effectiveness of a single aberration correction per optical slice in beam scanned optically sectioning microscopes. (2010)
Journal Article

A complete miniaturised genotyping system for the detection of single nucleotide polymorphisms in human DNA samples. (2009)
Journal Article

External Linearization of a MEMS Electrothermal Scanner with Application in a Confocal Microscope. (2009)
Journal Article

A CMOS time-resolved fluorescence lifetime analysis micro-system (2009)
Journal Article

We describe a CMOS-based micro-system for time-resolved fluorescence lifetime analysis. It comprises a 16 × 4 array of single-photon avalanche diodes (SPADs) fabricated in 0.35 μm high-voltage CMOS technology with in-pixel time-gated photon counting... Read More about A CMOS time-resolved fluorescence lifetime analysis micro-system.

Adaptive optics for deeper imaging of biological samples. (2009)
Journal Article

Optical microscopy has been a cornerstone of life science investigations since its first practical application around 400 years ago with the goal being subcellular resolution, three-dimensional images, at depth, in living samples. Nonlinear microscop... Read More about Adaptive optics for deeper imaging of biological samples..

Intracavity absorption spectrometry; A new technique for process analysis? (2008)
Journal Article

CMOS driven micro-pixel LEDs integrated with single photon avalanche diodes for time resolved fluorescence measurements (2008)
Journal Article

Investigation of dental samples using a 35 MHz focussed ultrasound piezocomposite transducer (2008)
Journal Article

Simultaneous imaging of subplasma membrane and bulk cytoplasmic average Ca2+ concentrations in single smooth muscle cells (2008)
Journal Article

Evaluation of fitness parameters used in an iterative approach to aberration correction in optical sectioning microscopy (2008)
Journal Article

Active focus-locking in an optically sectioning microscope utilizing a deformable membrane mirror (2008)
Journal Article

’Aether Drag’ and Moving Images (2008)
Journal Article

Individually-addressable flip-chip AlInGaN micropixelated light emitting diode arrays with high continuous and nanosecond output power (2008)
Journal Article

Simultaneous imaging of subplasma membrane & bulk cytoplasmic average Ca2+ concentrations in single smooth muscle cells (2008)
Journal Article

Transfer of orbital angular momentum from a super-continuum, white-light beam (2008)
Journal Article

Surface-Enhanced Raman Scattering Spectroscopy as a sensitive and selective technique for the detection of folic acid in water and human serum (2008)
Journal Article

Design of diffractive optical elements for beam shaping of micro-pixellated LED light to a tightly focused spot. (2008)
Journal Article

Tightly focused spots with small central lobes, high central intensity and low sidelobe intensity are desirable for many light-emitting diode based micro-projection system applications. Diffractive optical elements (DOEs) offer a potentially low cost... Read More about Design of diffractive optical elements for beam shaping of micro-pixellated LED light to a tightly focused spot..

Real time, ultra low concentration detection of analytes in solution by infrared intracavity laser absorption (2007)
Journal Article

Optical ferris wheel for ultracold atoms (2007)
Journal Article

Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source (2007)
Journal Article

Characterization of natural carious lesions by fluorescence spectroscopy at 405-nm excitation wavelength (2007)
Journal Article

Adaptive optics for enhanced signal in CARS microscopy (2007)
Journal Article

Development of fibre-optic confocal microscopy for detection and diagnosis of dental caries” (2007)
Journal Article

Optical sectioning microscopes with no moving parts using a micro-stripe array light emitting diode (2007)
Journal Article

Parametric Resonance of Optically Trapped Aerosols (2007)
Journal Article

Polarisation and image rotation induced by a rotating dielectric rod: a treatment in terms of optical angular momentum (2006)
Journal Article

Evaluation of enamel dental restoration interface by optical coherence tomography (2005)
Journal Article