Controlling picolitre droplet impact dynamics by tailoring the solid subsurface (2015)
Journal Article
Brown, P., Talbot, E., Wood, T., Egan, M., Wu, J., Sainic, K., …Badyal, J. (2015). Controlling picolitre droplet impact dynamics by tailoring the solid subsurface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 481, 215-221. https://doi.org/10.1016/j.colsurfa.2015.04.047

The oscillatory dynamics of picolitre water droplets following impact onto a range of hydrophobic surfaces is found to be influenced by the underlayer stiffness and thickness. The relative contributions of surface functionality versus subsurface hard... Read More about Controlling picolitre droplet impact dynamics by tailoring the solid subsurface.

ZIC1 and SOST immunohistochemistry staining of osteocytes and osteoblasts in femoral head tissue (2014)
Journal Article
Younis, S., Walker, J., Wu, J., Datta, H., & Tuck, S. (2014). ZIC1 and SOST immunohistochemistry staining of osteocytes and osteoblasts in femoral head tissue. Osteoporosis International, 25,

Do structural alterations mediated by enzymatic activities influence the mechanical properties of capsular biomembranes? (2014)
Conference Proceeding
Wu, J., Andrews, R., Quinlan, R., & Tholozan, F. (2014). Do structural alterations mediated by enzymatic activities influence the mechanical properties of capsular biomembranes?. In Proceedings of 10th International Congress on Membranes and Membrane Processes

A microgripper sensor device capable of detecting ion efflux from whole cells (2014)
Journal Article
Daunton, R., Wood, D., Gallant, A., & Kataky, R. (2014). A microgripper sensor device capable of detecting ion efflux from whole cells. RSC Advances, 4(92), 50536-50541. https://doi.org/10.1039/c4ra05052e

Electrothermally actuated microgripper sensor devices that are capable of simultaneous manipulation of live mouse oocytes and the sensing of potassium ion efflux are presented. The ion selective electrode technology applied to a microgripper device y... Read More about A microgripper sensor device capable of detecting ion efflux from whole cells.

The effect of tranexamic acid on artificial joint materials : a biomechanical study (the bioTRANX study) (2014)
Journal Article
Alshryda, S., Mason, J., Sarda, P., Lou, T., Stanley, M., Wu, J., & Unsworth, A. (2015). The effect of tranexamic acid on artificial joint materials : a biomechanical study (the bioTRANX study). Journal of Orthopaedics and Traumatology, 16(1), 27-34. https://doi.org/10.1007/s10195-014-0312-0

Background Tranexamic acid (TXA) has been successfully used to reduce bleeding in joint replacement. Recently local TXA has been advocated to reduce blood loss in total knee or hip replacement; however, this raised concerns about potential adverse ef... Read More about The effect of tranexamic acid on artificial joint materials : a biomechanical study (the bioTRANX study).

A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells (2014)
Journal Article
Wu, W., Tholozan, F., Goldberg, M., Bowen, L., Wu, J., & Quinlan, R. (2014). A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells. Experimental Eye Research, 120, 10-14. https://doi.org/10.1016/j.exer.2013.12.004

Fibroblast growth factors play a key role in regulating lens epithelial cell proliferation and differentiation via an anteroposterior gradient that exists between the aqueous and vitreous humours. FGF-2 is the most important for lens epithelial cell... Read More about A gradient of matrix-bound FGF-2 and perlecan is available to lens epithelial cells.

Factors influencing wear particle size, morphology and cell viability (2013)
Journal Article
Lal, S., Salpingidou, G., & Wu, J. (2013). Factors influencing wear particle size, morphology and cell viability

Mass transfer limitations (2013)
Journal Article
Field, R., & Wu, J. (2013). Mass transfer limitations. Desalination, 318, 118-124. https://doi.org/10.1016/j.desal.2013.01.025

The key process engineering differences between reverse osmosis (RO) forward osmosis (FO) and pressure retarded osmosis (PRO) are emphasized. Attention is drawn to the importance of mass transfer limitations which are more severe in FO than in other... Read More about Mass transfer limitations.

The synthesis of neurotensin antagonist SR 48692 for prostate cancer research (2013)
Journal Article
Baxendale, I., Cheung, S., Kitching, M., Ley, S., & Shearman, J. (2013). The synthesis of neurotensin antagonist SR 48692 for prostate cancer research. Bioorganic and Medicinal Chemistry, 21(14), 4378-4387. https://doi.org/10.1016/j.bmc.2013.04.075

An improved synthesis of the molecule SR 48692 is presented and its use as a neurotensin antagonist biological probe for use in cancer research is described. The preparation includes an number of enhanced chemical conversions and strategies to overco... Read More about The synthesis of neurotensin antagonist SR 48692 for prostate cancer research.

A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1 (2013)
Journal Article
Battilocchio, C., Deadman, B. J., Nikbin, N., Kitching, M. O., Baxendale, I. R., & Ley, S. V. (2013). A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1. Chemistry - A European Journal, 19(24), 7917-7930. https://doi.org/10.1002/chem.201300696

Here we report the direct comparison of a conventional batch mode synthesis of Meclinertant (SR48692, 1), a neurotensin receptor-1 antagonist, with its machine-assisted flow chemistry alternative. By using these enabling tools, combined with solid-su... Read More about A Machine-Assisted Flow Synthesis of SR48692: A Probe for the Investigation of Neurotensin Receptor-1.

Multiscale Modeling of Membrane Distillation: Some Theoretical Considerations (2013)
Journal Article
Field, R., Wu, H., & Wu, J. (2013). Multiscale Modeling of Membrane Distillation: Some Theoretical Considerations. Industrial & Engineering Chemistry Research, 52(26), 8822-8828. https://doi.org/10.1021/ie302363e

First, it is shown that the effective thickness of the membrane is the sum of the actual thickness, k0/UL, and λC/(UL) where k0 is the thermal conductivity of the membrane matrix, λ is the latent of vaporization of water, C is a parameter (defined as... Read More about Multiscale Modeling of Membrane Distillation: Some Theoretical Considerations.

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize (2012)
Journal Article
Seechurn, C. C. J., Kitching, M. O., Colacot, T. J., & Snieckus, V. (2012). Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize. Angewandte Chemie International Edition, 51(21), 5062-5085. https://doi.org/10.1002/anie.201107017

Organic chemistry - Directors extend their reach (2012)
Journal Article
Kitching, M. O., & Snieckus, V. (2012). Organic chemistry - Directors extend their reach. Nature, 486(7404), 478-479. https://doi.org/10.1038/486478a

Copper-Catalyzed Cross-Coupling Interrupted by an Opportunistic Smiles Rearrangement: An Efficient Domino Approach to Dibenzoxazepinones (2012)
Journal Article
Kitching, M. O., Hurst, T. E., & Snieckus, V. (2012). Copper-Catalyzed Cross-Coupling Interrupted by an Opportunistic Smiles Rearrangement: An Efficient Domino Approach to Dibenzoxazepinones. Angewandte Chemie International Edition, 51(12), 2925-2929. https://doi.org/10.1002/anie.201106786

Is Vitamin E Stabilised UHMWPE the Future Material for TKA? (2012)
Journal Article
Wu, J. (2012). Is Vitamin E Stabilised UHMWPE the Future Material for TKA?. Orthopaedic proceedings, 94-B(SUPP XL),

Ultra-high molecular weight polyethylene (UHMWPE) has been the gold standard material of choice for the load-bearing articulating surface in knee joint prostheses. However, the application of joint replacements to younger (aged < 64 years) and more a... Read More about Is Vitamin E Stabilised UHMWPE the Future Material for TKA?.

Degradable emulsion-templated scaffolds for tissue engineering from thiol– ene photopolymerisation (2012)
Journal Article
Caldwell, S., Johnson, D., Didsbury, M., Murray, B., Wu, J., Przyborski, S., & Cameron, N. (2012). Degradable emulsion-templated scaffolds for tissue engineering from thiol– ene photopolymerisation. Soft Matter, 8(40), 10344-10351. https://doi.org/10.1039/c2sm26250a

Emulsion templating has been used to prepare highly porous polyHIPE materials by thiol–ene photoinitiated network formation. Commercially available multifunctional thiols and acrylates were formulated into water-in-oil high internal phase emulsions (... Read More about Degradable emulsion-templated scaffolds for tissue engineering from thiol– ene photopolymerisation.

A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid (2012)
Journal Article
Battilocchio, C., Baxendale, I. R., Biava, M., Kitching, M. O., & Ley, S. V. (2012). A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid. Organic Process Research and Development, 16(5), 798-810. https://doi.org/10.1021/op300084z

The development of a new, high-yielding, scalable and safe process for the preparation of 2-aminoadamantane-2-carboxylic acid (1) is described. This geminal, functionalized achiral amino acid has been reported to possess interesting biological activi... Read More about A Flow-Based Synthesis of 2-Aminoadamantane-2-carboxylic Acid.

Biotribological study of large diameter ceramic-on-CFR-PEEK hip joint including fluid uptake, wear and frictional heating (2012)
Journal Article
Wang, Q., Wu, J., Unsworth, A., Briscoe, A., Jarman-Smith, M., Lowry, C., …Collins, S. (2012). Biotribological study of large diameter ceramic-on-CFR-PEEK hip joint including fluid uptake, wear and frictional heating. Journal of Materials Science: Materials in Medicine, 23(6), 1533-1542. https://doi.org/10.1007/s10856-012-4617-3

A novel material combination of a large diameter Biolox® Delta zirconia-toughened-alumina (ZTA) head and a pitch-based carbon fibre reinforced poly ether–ether-ketone (CFR-PEEK) MOTIS® cup has been studied. The acetabular cups were inclined at three... Read More about Biotribological study of large diameter ceramic-on-CFR-PEEK hip joint including fluid uptake, wear and frictional heating.

Comparative ageing behaviour of commercial, unworn and worn 3Y-TZP and zirconia-toughened alumina hip joint heads. (2012)
Journal Article
Douillard, T., Chevalier, J., Descamps-Mandine, A., Warner, I., Galais, Y., Whitaker, P., …Wang, Q. (2012). Comparative ageing behaviour of commercial, unworn and worn 3Y-TZP and zirconia-toughened alumina hip joint heads. Journal of the European Ceramic Society, 32(8), 1529-1540. https://doi.org/10.1016/j.jeurceramsoc.2012.01.003

There is a trend today to develop zirconia toughened alumina (ZTA) composites for orthopaedic applications. So far, there is limited data concerning their sensitivity to ageing, especially considering tests performed on implants produced on an indust... Read More about Comparative ageing behaviour of commercial, unworn and worn 3Y-TZP and zirconia-toughened alumina hip joint heads..

Scale-Up of Flow-Assisted Synthesis of C-2-Symmetric Chiral PyBox Ligands (2012)
Journal Article
Battilocchio, C., Baumann, M., Baxendale, I. R., Biava, M., Kitching, M. O., Ley, S. V., …Tappin, N. D. (2012). Scale-Up of Flow-Assisted Synthesis of C-2-Symmetric Chiral PyBox Ligands. Synthesis: Journal of Synthetic Organic Chemistry, 44(4), 635-647. https://doi.org/10.1055/s-0031-1289676

A series of PyBox ligands were prepared from commercially available chelidonic acid by a multistep flow sequence using mesoreactor technology. A chloro group introduced onto the ligand scaffold was subsequently exploited to give amine derivatives rea... Read More about Scale-Up of Flow-Assisted Synthesis of C-2-Symmetric Chiral PyBox Ligands.