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All Outputs (18)

Surface Modification of Polyesters Using Biosourced Soil-Release Polymers (2025)
Journal Article
Starck, M., Fiandra, E. F., Binks, J., Si, G., Chilton, R., Sivik, M., Thompson, R. L., Li, J., Wilson, M. R., & Mahon, C. S. (2025). Surface Modification of Polyesters Using Biosourced Soil-Release Polymers. JACS Au, 5(2), 666-674. https://doi.org/10.1021/jacsau.4c00908

Soil-release polymers (SRPs) are important components of fabric care formulations, performing important roles in the cleaning of synthetic fabrics. SRPs modify the surface of textiles and render materials resistant to staining, while offering environ... Read More about Surface Modification of Polyesters Using Biosourced Soil-Release Polymers.

Field-domain rapid-scan EPR at 240GHz for studies of protein functional dynamics at room temperature. (2024)
Journal Article
Price, B. D., Sojka, A., Maity, S., Chavez, I. M., Starck, M., Wilson, M. Z., Han, S., & Sherwin, M. S. (2024). Field-domain rapid-scan EPR at 240GHz for studies of protein functional dynamics at room temperature. Journal of Magnetic Resonance, 366, Article 107744. https://doi.org/10.1016/j.jmr.2024.107744

We present field-domain rapid-scan (RS) electron paramagnetic resonance (EPR) at 8.6T and 240GHz. To enable this technique, we upgraded a home-built EPR spectrometer with an FPGA-enabled digitizer and real-time processing software. The software lever... Read More about Field-domain rapid-scan EPR at 240GHz for studies of protein functional dynamics at room temperature..

Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes (2023)
Journal Article
De Rosa, D. F., Starck, M., Parker, D., & Pal, R. (2024). Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes. Chemistry - A European Journal, 30(9), Article e202303227. https://doi.org/10.1002/chem.202303227

Understanding the factors that shape the circularly polarised luminescence (CPL) emission profiles of europium(III)-based CPL emitters to have specific sign properties, e. g. monosignate individual CPL transitions, is key to design novel complexes fo... Read More about Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes.

Designing biodegradable alternatives to commodity polymers (2023)
Journal Article
Fiandra, E. F., Shaw, L., Starck, M., McGurk, C. J., & Mahon, C. S. (2023). Designing biodegradable alternatives to commodity polymers. Chemical Society Reviews, 23(52), 8085-8105. https://doi.org/10.1039/d3cs00556a

The development and widespread adoption of commodity polymers changed societal landscapes on a global scale. Without the everyday materials used in packaging, textiles, construction and medicine, our lives would be unrecognisable. Through decades of... Read More about Designing biodegradable alternatives to commodity polymers.

Terahertz EPR spectroscopy using a 36-tesla high-homogeneity series-connected hybrid magnet (2023)
Journal Article
Dubroca, T., Wang, X., Mentink-Vigier, F., Trociewitz, B., Starck, M., Parker, D., Sherwin, M. S., Hill, S., & Krzystek, J. (2023). Terahertz EPR spectroscopy using a 36-tesla high-homogeneity series-connected hybrid magnet. Journal of Magnetic Resonance, 353, Article 107480. https://doi.org/10.1016/j.jmr.2023.107480

Electron Paramagnetic Resonance (EPR) is a powerful technique to study materials and biological samples on an atomic scale. High-field EPR in particular enables extracting very small g-anisotropies in organic radicals and half-filled 3d and 4f metal... Read More about Terahertz EPR spectroscopy using a 36-tesla high-homogeneity series-connected hybrid magnet.

Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields (2023)
Journal Article
Maity, S., Price, B. D., Wilson, C. B., Mukherjee, A., Starck, M., Parker, D., Wilson, M. Z., Lovett, J. E., Han, S., & Sherwin, M. S. (2023). Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields. Angewandte Chemie International Edition, 62(13), Article e202212832. https://doi.org/10.1002/anie.202212832

We present time-resolved Gd−Gd electron paramagnetic resonance (TiGGER) at 240 GHz for tracking inter-residue distances during a protein's mechanical cycle in the solution state. TiGGER makes use of Gd-sTPATCN spin labels, whose favorable qualities i... Read More about Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields.

Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification (2022)
Journal Article
Fradgley, J. D., Starck, M., Lamarque, L., & Parker, D. (2022). Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification. European Journal of Inorganic Chemistry, 2022(32), Article e202200426. https://doi.org/10.1002/ejic.202200426

The synthesis and photophysical evaluation of a series of hydrophilic sulphonated and pH responsive luminescent europium(III) probes are reported. The Eu emission intensities and lifetimes increase very significantly on lowering pH, leading to a ‘swi... Read More about Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification.

Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function (2021)
Journal Article
Starck, M., Fradgley, J. D., De Rosa, D. F., Batsanov, A. S., Papa, M., Taylor, M. J., Lovett, J. E., Lutter, J. C., Allen, M. J., & Parker, D. (2021). Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function. Chemistry - A European Journal, 27(71), 17921-17927. https://doi.org/10.1002/chem.202103243

A series of cationic and neutral p−Br and p−NO2 pyridine substituted Eu(III) and Gd(III) coordination complexes serve as versatile synthetic intermediates. Nucleophilic aromatic substitution occurs readily at the para position under mild conditions,... Read More about Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function.

Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes (2021)
Journal Article
Parker, D., Fradgley, J. D., Delbianco, M., Starck, M., Walton, J., & Zwier, J. M. (2022). Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes. Faraday Discussions, 234, 159 - 174. https://doi.org/10.1039/d1fd00059d

The relative sensitivities of structurally related Eu(III) complexes to quenching by electron and energy transfer processes have been compared. In two sets of 9-coordinate complexes based on 1,4,7-triazacyclononane, the Eu emission lifetime decreased... Read More about Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes.

Targeted pH switched europium complexes monitoring receptor internalisation in living cells (2021)
Journal Article
Fradgley, J. D., Starck, M., Laget, M., Bourrier, E., Dupuis, E., Lamarque, L., Trinquet, E., Zwier, J. M., & Parker, D. (2021). Targeted pH switched europium complexes monitoring receptor internalisation in living cells. Chemical Communications, 57(47), 5814-5817. https://doi.org/10.1039/d1cc01029h

We report the design and evaluation of pH responsive luminescent europium(III) probes that allow conjugation to targeting vectors to monitor receptor internalisation in cells. The approach adopted here can be used to tag proteins selectively and to m... Read More about Targeted pH switched europium complexes monitoring receptor internalisation in living cells.

Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells (2020)
Journal Article
Starck, M., Fradgley, J. D., Pal, R., Zwier, J. M., Lamarque, L., & Parker, D. (2021). Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells. Chemistry - A European Journal, 27(2), 766-777. https://doi.org/10.1002/chem.202003992

A set of four luminescent Eu(III) complexes bearing an extended aryl‐alkynylpyridine chromophore has been studied, showing very different pH‐dependent behaviour in their absorption and emission spectral response. For two complexes with p K a values o... Read More about Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells.

Targeted Luminescent Europium Peptide Conjugates: Comparative Analysis Using Maleimide and para-Nitropyridyl Linkages for Organelle Staining (2019)
Journal Article
Starck, M., Fradgley, J. D., Di Vita, S., Mosely, J., Pal, R., & Parker, D. (2020). Targeted Luminescent Europium Peptide Conjugates: Comparative Analysis Using Maleimide and para-Nitropyridyl Linkages for Organelle Staining. Bioconjugate Chemistry, 31(2), 229-240. https://doi.org/10.1021/acs.bioconjchem.9b00735

The syntheses and photophysical behaviour of nine, strongly luminescent nonadentate Eu(III) complexes are reported. Each complex is based on N-functionalised 1,4,7- triazacyclononane, and linkage to other groups or targeting vectors can occur either... Read More about Targeted Luminescent Europium Peptide Conjugates: Comparative Analysis Using Maleimide and para-Nitropyridyl Linkages for Organelle Staining.

A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for Use in Double Electron Electron Resonance Distance Measurements (2019)
Journal Article
Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G. M., Parker, D., & Lovett, J. E. (2019). A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for Use in Double Electron Electron Resonance Distance Measurements. Inorganic Chemistry, 58(5), 3015-3025. https://doi.org/10.1021/acs.inorgchem.8b02892

The design, synthesis, and application of a nine-coordinate gadolinium(III)-containing spin label, [Gd.sTPATCN]-SL, for use in nanometer-distance measurement experiments by EPR spectroscopy is presented. The spin label links to cysteines via a short... Read More about A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for Use in Double Electron Electron Resonance Distance Measurements.

Interaction of Nucleotides with a Trinuclear Terbium(III)–Dizinc(II) Complex: Efficient Sensitization of Terbium Luminescence by Guanosine Monophosphate and Application to Real-Time Monitoring of Phosphodiesterase Activity (2018)
Journal Article
Aulsebrook, M. L., Starck, M., Grace, M. R., Graham, B., Thordarson, P., Pal, R., & Tuck, K. L. (2019). Interaction of Nucleotides with a Trinuclear Terbium(III)–Dizinc(II) Complex: Efficient Sensitization of Terbium Luminescence by Guanosine Monophosphate and Application to Real-Time Monitoring of Phosphodiesterase Activity. Inorganic Chemistry, 58(1), 495-505. https://doi.org/10.1021/acs.inorgchem.8b02731

An in-depth study of the interaction of a trinuclear terbium(III)–dizinc(II) complex with an array of nucleotides differing in the type of nucleobase and number of phosphate groups, as well as cyclic versus acyclic variants, is presented. The study e... Read More about Interaction of Nucleotides with a Trinuclear Terbium(III)–Dizinc(II) Complex: Efficient Sensitization of Terbium Luminescence by Guanosine Monophosphate and Application to Real-Time Monitoring of Phosphodiesterase Activity.

Enantioselective cellular localisation of europium(iii) coordination complexes (2017)
Journal Article
Frawley, A. T., Linford, H., Starck, M., Pal, R., & Parker, D. (2018). Enantioselective cellular localisation of europium(iii) coordination complexes. Chemical Science, 9(4), 1042-1049. https://doi.org/10.1039/c7sc04422d

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed b... Read More about Enantioselective cellular localisation of europium(iii) coordination complexes.

Responsive, Water-Soluble Europium(III) Luminescent Probes (2017)
Journal Article
Shuvaev, S., Starck, M., & Parker, D. (2017). Responsive, Water-Soluble Europium(III) Luminescent Probes. Chemistry - A European Journal, 23(42), 9974-9989. https://doi.org/10.1002/chem.201700567

The design principles, mechanism of action and performance of europium(III) complexes that serve as strongly emissive and responsive molecular probes in water are critically discussed. Examples of systems designed to assess pH, selected metal ions an... Read More about Responsive, Water-Soluble Europium(III) Luminescent Probes.

Structural Control of Cell Permeability with Highly Emissive Europium(III) Complexes Permits Different Microscopy Applications (2016)
Journal Article
Starck, M., Pal, R., & Parker, D. (2016). Structural Control of Cell Permeability with Highly Emissive Europium(III) Complexes Permits Different Microscopy Applications. Chemistry - A European Journal, 22(2), 570-580. https://doi.org/10.1002/chem.201504103

Four anionic europium complexes are described based on triazacyclononane tris-carboxylate or phosphinate ligands. In each case, the three sensitising chromophores comprise a substituted aryl–alkynyl pyridine group, with complex brightness in water fa... Read More about Structural Control of Cell Permeability with Highly Emissive Europium(III) Complexes Permits Different Microscopy Applications.