All Outputs (257)

Absolute measurements of state-to-state rotational energy transfer between CO and H2 at interstellar temperatures (2022)
Journal Article
Labiad, H., Fournier, M., Mertens, L. A., Faure, A., Carty, D., Stoecklin, T., …Sims, I. R. (2022). Absolute measurements of state-to-state rotational energy transfer between CO and H2 at interstellar temperatures. Physical Review A, 105(2), Article L020802. https://doi.org/10.1103/physreva.105.l020802

Experimental measurements and theoretical calculations of state-to-state rate coefficients for rotational energy transfer of CO in collision with H2 are reported at the very low temperatures prevailing in dense interstellar clouds (5–20 K). Detailed... Read More about Absolute measurements of state-to-state rotational energy transfer between CO and H2 at interstellar temperatures.

Application of suction monitoring for cyclic triaxial testing of compacted soils (2022)
Journal Article
Kumar, A., Azizi, A., & Toll, D. (2022). Application of suction monitoring for cyclic triaxial testing of compacted soils. Journal of Geotechnical and Geoenvironmental Engineering, 148(4), https://doi.org/10.1061/%28asce%29gt.1943-5606.0002766

The performance of compacted soils that are used for the construction of railway embankments are impacted by weather-driven suction and water content fluctuations. Hence, the accurate measurement of the water retention properties of soil during cycli... Read More about Application of suction monitoring for cyclic triaxial testing of compacted soils.

Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability (2022)
Journal Article
Hudhud, L., Chisholm, D. R., Whiting, A., Steib, A., Pohóczky, K., Kecskés, A., …Helyes, Z. (2022). Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability. Molecules, 27(3), Article 977. https://doi.org/10.3390/molecules27030977

All-trans-retinoic acid (ATRA), the active metabolite of vitamin A, plays a pivotal role in cell differentiation, proliferation and embryonic development. It is an effective therapy for dermatological disorders and malignancies. ATRA is prone to isom... Read More about Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability.

Circularly polarised luminescence laser scanning confocal microscopy to study live cell chiral molecular interactions (2022)
Journal Article
Stachelek, P., MacKenzie, L., Parker, D., & Pal, R. (2022). Circularly polarised luminescence laser scanning confocal microscopy to study live cell chiral molecular interactions. Nature Communications, 13(1), Article 533. https://doi.org/10.1038/s41467-022-28220-z

The molecular machinery of life is founded on chiral building blocks, but no experimental technique is currently available to distinguish or monitor chiral systems in live cell bio-imaging studies. Luminescent chiral molecules encode a unique optical... Read More about Circularly polarised luminescence laser scanning confocal microscopy to study live cell chiral molecular interactions.

Behavioural responses of non-breeding waterbirds to marine traffic in the near-shore environment (2021)
Journal Article
Jarrett, D., Calladine, J., Cook, A. S., Upton, A., Williams, J., Williams, S., …Humphreys, E. M. (2021). Behavioural responses of non-breeding waterbirds to marine traffic in the near-shore environment. Bird Study, 68(4), 443-454. https://doi.org/10.1080/00063657.2022.2113855

Capsule: Recording of behavioural responses to ferry traffic for 11 target species showed that Red-throated Diver Gavia stellata, Slavonian Grebe Podiceps auratus, and Black-throated Diver Gavia arctica were most likely to react to passing vessels. A... Read More about Behavioural responses of non-breeding waterbirds to marine traffic in the near-shore environment.

Coupling cyclic and water retention response of a clayey sand subjected to traffic and environmental cycles (2021)
Journal Article
Azizi, A., Kumar, A., & Toll, D. G. (2023). Coupling cyclic and water retention response of a clayey sand subjected to traffic and environmental cycles. Géotechnique, 73(5), 401-417. https://doi.org/10.1680/jgeot.21.00063

Compacted soils used as formation layers of railways and roads continuously undergo water content and suction changes due to seasonal variations. Such variations, together with the impact of cyclic traffic-induced loads, can alter the hydro-mechanica... Read More about Coupling cyclic and water retention response of a clayey sand subjected to traffic and environmental cycles.

Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function (2021)
Journal Article
Starck, M., Fradgley, J. D., De Rosa, D. F., Batsanov, A. S., Papa, M., Taylor, M. J., …Parker, D. (2021). Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function. Chemistry - A European Journal, 27(71), 17921-17927. https://doi.org/10.1002/chem.202103243

A series of cationic and neutral p−Br and p−NO2 pyridine substituted Eu(III) and Gd(III) coordination complexes serve as versatile synthetic intermediates. Nucleophilic aromatic substitution occurs readily at the para position under mild conditions,... Read More about Versatile Para‐Substituted Pyridine Lanthanide Coordination Complexes Allow Late Stage Tailoring of Complex Function.

Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes (2021)
Journal Article
Parker, D., Fradgley, J. D., Delbianco, M., Starck, M., Walton, J., & Zwier, J. M. (2022). Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes. Faraday Discussions, 234, 159 - 174. https://doi.org/10.1039/d1fd00059d

The relative sensitivities of structurally related Eu(III) complexes to quenching by electron and energy transfer processes have been compared. In two sets of 9-coordinate complexes based on 1,4,7-triazacyclononane, the Eu emission lifetime decreased... Read More about Comparative analysis of lanthanide excited state quenching by electronic energy and electron transfer processes.

The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses (2021)
Journal Article
Picton, D., Luyten, Y., Morgan, R., Nelson, A., Smith, D., Dryden, D., …Blower, T. (2021). The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses. Nucleic Acids Research, 49(19), 11257-11273. https://doi.org/10.1093/nar/gkab906

Bacteria have evolved a multitude of systems to prevent invasion by bacteriophages and other mobile genetic elements. Comparative genomics suggests that genes encoding bacterial defence mechanisms are often clustered in “defence islands”, providing a... Read More about The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.

The design of responsive luminescent lanthanide probes and sensors (2021)
Journal Article
Parker, D., Fradgley, J. D., & Wong, K. (2021). The design of responsive luminescent lanthanide probes and sensors. Chemical Society Reviews, 50(14), 8193-8213. https://doi.org/10.1039/d1cs00310k

The principles of the design of responsive luminescent probes and sensors based on lanthanide emission are summarised, based on a mechanistic understanding of their mode of action. Competing kinetic pathways for deactivation of the excited states tha... Read More about The design of responsive luminescent lanthanide probes and sensors.

Predictive and prescriptive analytics in transportation geotechnics: Three case studies (2021)
Journal Article
Tinoco, J., Parente, M., Gomes Correia, A., Cortez, P., & Toll, D. (2021). Predictive and prescriptive analytics in transportation geotechnics: Three case studies. Transportation Engineering, 5, Article 100074. https://doi.org/10.1016/j.treng.2021.100074

Transportation infrastructure is of paramount importance for any country. The construction, management and maintenance of this infrastructure is a complex task that requires a significant amount of resources (e.g., human work equipment, materials, ma... Read More about Predictive and prescriptive analytics in transportation geotechnics: Three case studies.

Targeted pH switched europium complexes monitoring receptor internalisation in living cells (2021)
Journal Article
Fradgley, J. D., Starck, M., Laget, M., Bourrier, E., Dupuis, E., Lamarque, L., Trinquet, E., Zwier, J. M., & Parker, D. (2021). Targeted pH switched europium complexes monitoring receptor internalisation in living cells. Chemical Communications, 57(47), 5814-5817. https://doi.org/10.1039/d1cc01029h

We report the design and evaluation of pH responsive luminescent europium(III) probes that allow conjugation to targeting vectors to monitor receptor internalisation in cells. The approach adopted here can be used to tag proteins selectively and to m... Read More about Targeted pH switched europium complexes monitoring receptor internalisation in living cells.

Material Responses to the Great Depression in Northeast England (2021)
Journal Article
Petts, D., O’Donnell, R., & Armstrong, K. (2021). Material Responses to the Great Depression in Northeast England. International Journal of Historical Archaeology, 25(4), 1165-1193. https://doi.org/10.1007/s10761-021-00595-7

The Great Depression of the 1920s and 1930s was a global economic crisis, yet to understand its impacts in material terms, it is necessary to recognize that they were situated within specific local and regional contexts. This article, drawing on the... Read More about Material Responses to the Great Depression in Northeast England.

Striking solvent dependence of total emission and circularly polarised luminescence in coordinatively saturated chiral europium complexes: solvation significantly perturbs the ligand field (2021)
Journal Article
Fradgley, J. D., Frawley, A. T., Pal, R., & Parker, D. (2021). Striking solvent dependence of total emission and circularly polarised luminescence in coordinatively saturated chiral europium complexes: solvation significantly perturbs the ligand field. Physical Chemistry Chemical Physics, 23(19), 11479-11487. https://doi.org/10.1039/d1cp01686e

Examination of total emission and circularly polarised luminescence (CPL) spectra of three 9-coordinate Eu(III) complexes with well-defined speciation shows that the ligand fields of these C3 symmetric complexes are extremely sensitive to solvent pol... Read More about Striking solvent dependence of total emission and circularly polarised luminescence in coordinatively saturated chiral europium complexes: solvation significantly perturbs the ligand field.

Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing blood-stream infection in Malawi (2021)
Journal Article
Rodwell, E., Wenner, N., Pulford, C., Cai, Y., Bowers-Barnard, A., Beckett, A., …Perez-Sepulveda, B. (2021). Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing blood-stream infection in Malawi. Viruses, 13(3), Article 478. https://doi.org/10.3390/v13030478

In recent years, novel lineages of invasive non-typhoidal Salmonella (iNTS) serovars Typhimurium and Enteritidis have been identified in patients with bloodstream infection in sub-Saharan Africa. Here, we isolated and characterised 32 phages capable... Read More about Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing blood-stream infection in Malawi.

Advanced analysis of satellite data reveals ground deformation precursors to the Brumadinho Tailings Dam collapse (2021)
Journal Article
Grebby, S., Sowter, A., Gluyas, J., Toll, D., Gee, D., Athab, A., & Girindran, R. (2021). Advanced analysis of satellite data reveals ground deformation precursors to the Brumadinho Tailings Dam collapse. Communications Earth & Environment, 2, Article 2. https://doi.org/10.1038/s43247-020-00079-2

Catastrophic failure of a tailings dam at an iron ore mine complex in Brumadinho, Brazil, on 25th January 2019 released 11.7 million m3 of tailings downstream. Although reportedly monitored using an array of geotechnical techniques, the collapse occu... Read More about Advanced analysis of satellite data reveals ground deformation precursors to the Brumadinho Tailings Dam collapse.

Lanthanide–Cyclen–Camptothecin Nanocomposites for Cancer Theranostics Guided by Near-Infrared and Magnetic Resonance Imaging (2021)
Journal Article
Zhang, Y., Ma, X., Chau, H., Thor, W., Jiang, L., Zha, S., …Wong, K. (2021). Lanthanide–Cyclen–Camptothecin Nanocomposites for Cancer Theranostics Guided by Near-Infrared and Magnetic Resonance Imaging. ACS Applied Nano Material, 4(1), 271-278. https://doi.org/10.1021/acsanm.0c02597

We have devised a molecular-to-micellar strategy to incorporate a lanthanide nanoplatform for the delivery of an anticancer drug that simultaneously offers hybrid near-infrared (NIR) and magnetic resonance imaging (MRI) capabilities with defined lant... Read More about Lanthanide–Cyclen–Camptothecin Nanocomposites for Cancer Theranostics Guided by Near-Infrared and Magnetic Resonance Imaging.

Weather-driven deterioration processes affecting the performance of embankment slopes (2020)
Journal Article
Stirling, R., Toll, D., Glendinning, S., Helm, P., Yildiz, A., Hughes, P., & Asquith, J. (2021). Weather-driven deterioration processes affecting the performance of embankment slopes. Géotechnique, 71(11), 957-969. https://doi.org/10.1680/jgeot.19.sip.038

Deterioration of earthworks and the resultant implications for serviceability and increased occurrence of failures have a significant negative impact on transport networks both in the UK and internationally. There is evidence in the field that deteri... Read More about Weather-driven deterioration processes affecting the performance of embankment slopes.

Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells (2020)
Journal Article
Starck, M., Fradgley, J. D., Pal, R., Zwier, J. M., Lamarque, L., & Parker, D. (2021). Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells. Chemistry - A European Journal, 27(2), 766-777. https://doi.org/10.1002/chem.202003992

A set of four luminescent Eu(III) complexes bearing an extended aryl‐alkynylpyridine chromophore has been studied, showing very different pH‐dependent behaviour in their absorption and emission spectral response. For two complexes with p K a values o... Read More about Synthesis and Evaluation of Europium Complexes that Switch On Luminescence in Lysosomes of Living Cells.

Cellular localisation of structurally diverse diphenylacetylene fluorophores (2020)
Journal Article
Chisholm, D. R., Hughes, J. G., Blacker, T. S., Humann, R., Adams, C., Callaghan, D., …Whiting, A. (2020). Cellular localisation of structurally diverse diphenylacetylene fluorophores. Organic and Biomolecular Chemistry, 18(45), 9231-9245. https://doi.org/10.1039/d0ob01153c

Fluorescent probes are increasingly used as reporter molecules in a wide variety of biophysical experiments, but when designing new compounds it can often be difficult to anticipate the effect that changing chemical structure can have on cellular loc... Read More about Cellular localisation of structurally diverse diphenylacetylene fluorophores.