An Efficient Route To S-N-(9-Fluorenylmethoxycarbonyl)-4'-(1-Azi-2,2,2-Trifluoroethyl)phenylalanine

Fishwick, C.W.G.; Sanderson, J.M.; Findlay, J.B.C.

Abstract

An extremely efficient synthesis of optically pure photoactivatable phenylalanine derivative 1 is described. The key step involves a highly diastereoselective alkylation of a chiral glycine equivalent.

Citation

Fishwick, C., Sanderson, J., & Findlay, J. (1994). An Efficient Route To S-N-(9-Fluorenylmethoxycarbonyl)-4'-(1-Azi-2,2,2-Trifluoroethyl)phenylalanine. Tetrahedron Letters, 35(26), 4611-4614. https://doi.org/10.1016/s0040-4039%2800%2960743-8

• Journal Article Type: Article
• Publication Date: 1994-06
• Journal: Tetrahedron Letters
• Print ISSN: 0040-4039
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 35
• Issue: 26
• Pages: 4611-4614
• DOI: https://doi.org/10.1016/s0040-4039%2800%2960743-8
• Keywords: Photoaffinity labelling, diazirine, phenylalanine
• Public URL: https://durham-repository.worktribe.com/output/1554551