Lucy J. Rowlands
17O NMR spectroscopy as a tool to study hydrogen bonding of cholesterol in lipid bilayers
Rowlands, Lucy J.; Marks, Adam; Sanderson, John M.; Law, Robert V.
Dr John Sanderson firstname.lastname@example.org
Robert V. Law
Cholesterol is a crucial component of biological membranes and can interact with other membrane components through hydrogen bonding. NMR spectroscopy has been used previously to investigate this bonding, however this study represents the first 17O NMR spectroscopy study of isotopically enriched cholesterol. We demonstrate the 17O chemical shift is dependent on hydrogen bonding, providing a novel method for the study of cholesterol in bilayers.
Rowlands, L. J., Marks, A., Sanderson, J. M., & Law, R. V. (2020). 17O NMR spectroscopy as a tool to study hydrogen bonding of cholesterol in lipid bilayers. Chemical Communications, 56(92), 14499-14502. https://doi.org/10.1039/d0cc05466f
|Journal Article Type||Article|
|Acceptance Date||Oct 28, 2020|
|Online Publication Date||Nov 5, 2020|
|Publication Date||Nov 28, 2020|
|Deposit Date||Nov 5, 2020|
|Publicly Available Date||Feb 8, 2021|
|Publisher||Royal Society of Chemistry|
|Peer Reviewed||Peer Reviewed|
Published Journal Article
Publisher Licence URL
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
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