Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome (2022)
Journal Article
Guillen-Garcia, A., Gibson, S., Jordan, C., Ramaswamy, V., Linthwaite, V., Bromley, E., …Cann, M. (2022). Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome. Nature Communications, 13, Article 5289. https://doi.org/10.1038/s41467-022-32925-6

Light harvesting is fundamental for production of ATP and reducing equivalents for CO2 fixation during photosynthesis. However, electronic energy transfer (EET) through a photosystem can harm the photosynthetic apparatus when not balanced with CO2. H... Read More about Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome.

Modulated Fluorescence in LB Films Based on DADQs—A Potential Sensing Surface? (2022)
Journal Article
Szablewski, M., Thompson, R. L., & Pålsson, L. (2022). Modulated Fluorescence in LB Films Based on DADQs—A Potential Sensing Surface?. Molecules, 27(12), Article 3893. https://doi.org/10.3390/molecules27123893

Novel fluorescent Langmuir-Blodgett (LB) films have been constructed from three different amphiphilic dicynaoquinodimethanes (DADQs). The DADQs varied in functional group structure, which had an impact on the LB film structure and the fluorescence pr... Read More about Modulated Fluorescence in LB Films Based on DADQs—A Potential Sensing Surface?.

Applying TADF Emitters in Bioimaging and Sensing—A Novel Approach Using Liposomes for Encapsulation and Cellular Uptake (2021)
Journal Article
Smith, P. O., Black, D. J., Pal, R., Avó, J., Dias, F. B., Linthwaite, V. L., …Pålsson, L. (2021). Applying TADF Emitters in Bioimaging and Sensing—A Novel Approach Using Liposomes for Encapsulation and Cellular Uptake. Frontiers in Chemistry, 9, Article 743928. https://doi.org/10.3389/fchem.2021.743928

A new method for facilitating the delivery, uptake and intracellular localisation of thermally activated delayed fluorescence (TADF) complexes was developed. First, confinement of TADF complexes in liposomes was demonstrated, which were subsequently... Read More about Applying TADF Emitters in Bioimaging and Sensing—A Novel Approach Using Liposomes for Encapsulation and Cellular Uptake.

TADF Dye-Loaded Nanoparticles for Fluorescence Live-Cell Imaging (2020)
Journal Article
Crucho, C. I., Avó, J., Diniz, A. M., Pinto, S. N., Barbosa, J., Smith, P. O., …Dias, F. B. (2020). TADF Dye-Loaded Nanoparticles for Fluorescence Live-Cell Imaging. Frontiers in Chemistry, 8, Article 404. https://doi.org/10.3389/fchem.2020.00404

Thermally activated delayed fluorescence (TADF) molecules offer nowadays a powerful tool in the development of novel organic light emitting diodes due to their capability of harvesting energy from non-emissive triplet states without using heavy-metal... Read More about TADF Dye-Loaded Nanoparticles for Fluorescence Live-Cell Imaging.

A bacteriophage mimic of the bacterial nucleoid-associated protein Fis (2020)
Journal Article
Sharples, G. J., Heddle, J. G., Kozak, M., Taube, M., Hughes, T. R., Pålsson, L., …Chakraborti, S. (2020). A bacteriophage mimic of the bacterial nucleoid-associated protein Fis. Biochemical Journal, 477(7), 1345-1362. https://doi.org/10.1042/bcj20200146

We report the identification and characterization of a bacteriophage λ-encoded protein, NinH. Sequence homology suggests similarity between NinH and Fis, a bacterial nucleoid-associated protein involved in numerous DNA topology manipulations, includi... Read More about A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.

Almost complete radiationless energy transfer from excited triplet state of a dim phosphor to a covalently linked adjacent fluorescent dye in purely organic tandem luminophores doped into PVA matrix (2019)
Journal Article
Jõgela, J., Uri, A., Pålsson, L., & Enkvist, E. (2019). Almost complete radiationless energy transfer from excited triplet state of a dim phosphor to a covalently linked adjacent fluorescent dye in purely organic tandem luminophores doped into PVA matrix. Journal of Materials Chemistry C Materials for optical and electronic devices, 7(22), 6571-6577. https://doi.org/10.1039/c8tc05325a

In solid PVA matrix some thiophene- and selenophene-comprising heteroaromatic compounds reveal moderate room temperature phosphorescence with emission peaks between 550 and 600 nm and possessing lifetime in millisecond range upon excitation with near... Read More about Almost complete radiationless energy transfer from excited triplet state of a dim phosphor to a covalently linked adjacent fluorescent dye in purely organic tandem luminophores doped into PVA matrix.

In Vitro and in Cellulo Sensing of Transition Metals Using Time-Resolved Fluorescence Spectroscopy and Microscopy (2018)
Journal Article
Pal, R., Barker, A. C., Hummel, D., & Pålsson, L. (2019). In Vitro and in Cellulo Sensing of Transition Metals Using Time-Resolved Fluorescence Spectroscopy and Microscopy. Journal of Fluorescence, 29(1), 255-263. https://doi.org/10.1007/s10895-018-2335-z

In this work we demonstrate that time domain techniques can be used successfully to monitor realtively weak modulations of the fluorescence in sensing applications. The metal sensing complex Newport Green DCF™ can detect selected transition metals in... Read More about In Vitro and in Cellulo Sensing of Transition Metals Using Time-Resolved Fluorescence Spectroscopy and Microscopy.

The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor (2017)
Journal Article
Townsend, P., Dixon, C., Slootweg, E., Sukarta, O., Yang, A., Hughes, T., …Cann, M. (2018). The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor. Journal of Biological Chemistry, 293(9), 3218-3233. https://doi.org/10.1074/jbc.ra117.000485

Plant NLR proteins enable the immune system to recognise and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming and some NLRs have been shown to act in the nucleus and interact with transcription fa... Read More about The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor.

A tight tunable range for Ni(II) sensing and buffering in cells (2017)
Journal Article
Foster, A., Pernil, R., Patterson, C., Scott, A., Pålsson, L., Pal, R., …Robinson, N. (2017). A tight tunable range for Ni(II) sensing and buffering in cells. Nature Chemical Biology, 13(4), 409-414. https://doi.org/10.1038/nchembio.2310

The metal affinities of metal-sensing transcriptional regulators co-vary with cellular metal concentrations over more than 12 orders of magnitude. To understand the cause of this relationship, we determined the structure of the Ni(II) sensor InrS and... Read More about A tight tunable range for Ni(II) sensing and buffering in cells.

Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains (2016)
Journal Article
Sansee, A., Meksawangwong, S., Chainok, K., Franz, K., Gal, M., Palsson, L. -., …Kielar, F. (2016). Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. Dalton Transactions, 45(43), 17420-17430. https://doi.org/10.1039/c6dt02776h

Herein we report the synthesis and investigation of the properties of two tris-cyclometalated luminescent iridium complexes. These complexes are the simple derivatives of fac-[Ir(ppy)3] bearing amino alkyl groups on one of the phenylpyridine rings. T... Read More about Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.

The tomato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor I-2 couples DNA-Binding to Nucleotide-Binding Domain Nucleotide Exchange (2015)
Journal Article
Fenyk, S., Dixon, C., Kittens, W., Townsend, P., Sharpies, G., Pålsson, L., …Cann, M. (2016). The tomato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor I-2 couples DNA-Binding to Nucleotide-Binding Domain Nucleotide Exchange. Journal of Biological Chemistry, 291(3), 1137-1147. https://doi.org/10.1074/jbc.m115.698589

Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable plants to recognise and respond to pathogen attack. Previously, we demonstrated that the Rx1 NLR of potato is able to bind and bend DNA in vitro. DNA binding in situ requires its genu... Read More about The tomato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor I-2 couples DNA-Binding to Nucleotide-Binding Domain Nucleotide Exchange.

Chiral probe development for circularly polarised luminescence: comparative study of structural factors determining the degree of induced CPL with four heptacoordinate europium(III) complexes (2015)
Journal Article
Neil, E., Fox, M., Pal, R., Pålsson, L., O'Sullivan, B., & Parker, D. (2015). Chiral probe development for circularly polarised luminescence: comparative study of structural factors determining the degree of induced CPL with four heptacoordinate europium(III) complexes. Dalton Transactions, 44(33), 14937-14951. https://doi.org/10.1039/c5dt02358k

A series of bright, europium(III) complexes has been prepared based on an achiral heptadentate triazacyclononane ligand bearing two strongly absorbing, coordinated aralkynyl pyridyl moieties. The binding of chiral carboxylates, including α-hydroxy ac... Read More about Chiral probe development for circularly polarised luminescence: comparative study of structural factors determining the degree of induced CPL with four heptacoordinate europium(III) complexes.

The Potato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor Rx1 is a Pathogen Dependent DNA-Deforming Protein (2015)
Journal Article
Fenyk, S., Townsend, P. D., Dixon, C. H., Spies, G. B., de San Eustaquio Campillo, A., Slootweg, E. J., …Cann, M. J. (2015). The Potato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor Rx1 is a Pathogen Dependent DNA-Deforming Protein. Journal of Biological Chemistry, 290(41), 24945-24960. https://doi.org/10.1074/jbc.m115.672121

Plant NLR proteins enable cells to respond to pathogen attack. Several NLRs act in the nucleus, however, conserved nuclear targets that support their role in immunity are unknown. Previously we noted a structural homology between the NB domain of NLR... Read More about The Potato Nucleotide-Binding Leucine-Rich Repeat (NLR) Immune Receptor Rx1 is a Pathogen Dependent DNA-Deforming Protein.

Sensing properties of light-emitting single walled carbon nanotubes prepared via click chemistry of ylides bound to the nanotube surface (2015)
Journal Article
Bayazit, M., Pålsson, L., & Coleman, K. (2015). Sensing properties of light-emitting single walled carbon nanotubes prepared via click chemistry of ylides bound to the nanotube surface. RSC Advances, 5(46), 36865-36873. https://doi.org/10.1039/c5ra04330a

Pyridinium ylide functionalized single-walled carbon nanotubes (SWCNTs) generated from simple quaternary pyridinium salts covalently bound to the SWCNT surface undergo a 1, 3 dipolar cycloaddition with dimethyl acetylenedicarboxylate in a ‘click’ che... Read More about Sensing properties of light-emitting single walled carbon nanotubes prepared via click chemistry of ylides bound to the nanotube surface.

Oligo(p-phenyleneethynylene) (OPE) Molecular Wires: Synthesis and Length Dependence of Photoinduced Charge Transfer in OPEs with Triarylamine and Diaryloxadiazole End Groups (2015)
Journal Article
Linton, K., Fox, M., Pålsson, L., & Bryce, M. (2015). Oligo(p-phenyleneethynylene) (OPE) Molecular Wires: Synthesis and Length Dependence of Photoinduced Charge Transfer in OPEs with Triarylamine and Diaryloxadiazole End Groups. Chemistry - A European Journal, 21(10), 3997-4007. https://doi.org/10.1002/chem.201406080

The systematic synthesis and photophysical, electrochemical and computational studies on an extended series of triphenylamine-[C[TRIPLE BOND]C-1,4-C6H2(OR)2]n-C[TRIPLE BOND]C-diphenyl-1,3,4-oxadiazole dyad molecules (the OR groups are at 2,5-position... Read More about Oligo(p-phenyleneethynylene) (OPE) Molecular Wires: Synthesis and Length Dependence of Photoinduced Charge Transfer in OPEs with Triarylamine and Diaryloxadiazole End Groups.

Ultrafast Dynamics and Computational Studies on Diaminodicyanoquinodimethanes (DADQs) (2014)
Journal Article
Szablewski, M., Fox, M., Dias, F., Namih, H., Snedden, E., King, S., …Pålsson, L. (2014). Ultrafast Dynamics and Computational Studies on Diaminodicyanoquinodimethanes (DADQs). Journal of Physical Chemistry B (Soft Condensed Matter and Biophysical Chemistry), 118(24), 6815-6828. https://doi.org/10.1021/jp411358d

Three diaminodicyanoquinodimethanes, 4-(R1R2C)-1-[(NC)2C]-C6H4 (R1,R2 = H2N, 1; R1 = 3,5-Me2-4-OCH4H6N–, R2 = H2N, 2; R1 = 3,5-Me2-4-OCH4H6N–, R2 = 4-Me-C5H9N, 3), were investigated using carbon-13 NMR, steady-state, and ultrafast transient absorptio... Read More about Ultrafast Dynamics and Computational Studies on Diaminodicyanoquinodimethanes (DADQs).

Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes (2014)
Journal Article
Carr, R., Puckrin, R., McMahon, B. K., Pal, R., Parker, D., & Pålsson, L. (2014). Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes. Methods and Applications in Fluorescence, 2(2), Article 024007. https://doi.org/10.1088/2050-6120/2/2/024007

A circularly polarized luminescence (CPL) spectrometer has been built and used to study the binding interaction of lactate and four different proteins with racemic EuIII and TbIII complexes in aqueous solution. Lactate binding gives rise to strong in... Read More about Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes.

Regiospecific Formation and Unusual Optical Properties of 2,5-Bis(arylethynyl)rhodacyclopentadienes: A New Class of Luminescent Organometallics (2014)
Journal Article
Steffen, A., Ward, R., Tay, M., Edkins, R., Seeler, F., van Leeuwen, M., …Marder, T. (2014). Regiospecific Formation and Unusual Optical Properties of 2,5-Bis(arylethynyl)rhodacyclopentadienes: A New Class of Luminescent Organometallics. Chemistry - A European Journal, 20(3), 3652-3666. https://doi.org/10.1002/chem.201304068

A series of 2,5-bis(arylethynyl)rhodacyclopentadienes has been prepared by a rare example of regiospecific reductive coupling of 1,4-(p-R-phenyl)-1,3-butadiynes (R[DOUBLE BOND]H, Me, OMe, SMe, NMe2, CF3, CO2Me, CN, NO2, −C[TRIPLE BOND]C-(p-C6H4[BOND]... Read More about Regiospecific Formation and Unusual Optical Properties of 2,5-Bis(arylethynyl)rhodacyclopentadienes: A New Class of Luminescent Organometallics.

Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors. (2013)
Journal Article
Kasari, M., Ligi, K., Gareth Williams, J., Vaasa, A., Enkvist, E., Viht, K., …Uri, A. (2013). Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors. BBA - Proteins and Proteomics, 1834(7), 1330-1335. https://doi.org/10.1016/j.bbapap.2013.02.039

Responsive ARC-Lum probes were used for measurement of the concentration of active protein kinases (PKs) and determination of affinity of inhibitors of PKs. ARC-Lum probes incorporate thiophene or a selenophene heterocycle and a fluorophore conjugate... Read More about Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors..

Colour tuning of blue electroluminescence using bipolar carbazole-oxadiazole molecules in single-active-layer organic light emitting devices (OLEDs) (2012)
Journal Article
Linton, K., Fisher, A., Pearson, C., Fox, M., Pålsson, L., Bryce, M., & Petty, M. (2012). Colour tuning of blue electroluminescence using bipolar carbazole-oxadiazole molecules in single-active-layer organic light emitting devices (OLEDs). Journal of materials chemistry, 22(23), 11816-11825. https://doi.org/10.1039/c2jm31825c