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Professor Peter Craig's Outputs (46)

Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides (2024)
Journal Article
Mohimont, L., Anagnostopoulos, C., Anastassiadou, M., Castoldi, A. F., Cavelier, A., Coja, T., Craig, P., Crivellente, F., Dujardin, B., Hart, A., Hooghe, W., Jarrah, S., Machera, K., Menegola, E., Metruccio, F., & Sieke, C. (2024). Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides. Reproductive Toxicology, 130, Article 108741. https://doi.org/10.1016/j.reprotox.2024.108741

In 2022, the European Food Safety Authority (EFSA) conducted a dietary cumulative risk assessment for active substances of plant protection products on two types of craniofacial alterations: 1) craniofacial alterations due to abnormal skeletal develo... Read More about Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides.

Climate warming shifts riverine macroinvertebrate communities to be more sensitive to chemical pollutants (2024)
Journal Article
Sinclair, T., Craig, P., & Maltby, L. L. (2024). Climate warming shifts riverine macroinvertebrate communities to be more sensitive to chemical pollutants. Global Change Biology, 30(4), Article e17254. https://doi.org/10.1111/gcb.17254

Freshwaters are highly threatened ecosystems that are vulnerable to chemical pollution and climate change. Freshwater taxa vary in their sensitivity to chemicals and changes in species composition can potentially affect the sensitivity of assemblages... Read More about Climate warming shifts riverine macroinvertebrate communities to be more sensitive to chemical pollutants.

Spatial variation in the sensitivity of freshwater macroinvertebrate assemblages to chemical stressors (2023)
Journal Article
Liang, R., Sinclair, T. M., Craig, P. S., & Maltby, L. (2024). Spatial variation in the sensitivity of freshwater macroinvertebrate assemblages to chemical stressors. Water Research, 248, Article 120854. https://doi.org/10.1016/j.watres.2023.120854


Assessing spatial variation in the chemical sensitivity of natural assemblages will enhance ecological relevance and reduce uncertainty in ecological risk assessments and the derivation of environmental quality standards (EQSs). Ho... Read More about Spatial variation in the sensitivity of freshwater macroinvertebrate assemblages to chemical stressors.

Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks (2022)
Journal Article
Hoffmann, S., Aiassa, E., Angrish, M., Beausoleil, C., Bois, F., Ciccolallo, L., Craig, P., de Vries, R., Dorne, J., Druwe, I., Edwards, S., Eskes, C., Georgiadis, M., Hartung, T., Kienzler, A., Kristjansson, E., Lam, J., Martino, L., Meek, B., Morgan, R., …Tsaioun, K. (2022). Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX - Alternatives to Animal Experimentation, 39(3), 499-518. https://doi.org/10.14573/altex.2202141

The workshop titled “Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks” was co-organized by the Evidence-based Toxicology Collaboration and the European Food Safety Authority (EFSA) and hosted by EFSA... Read More about Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks.

Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid (2020)
Journal Article
Craig, P. S., Dujardin, B., Hart, A., Hernandez‐Jerez, A. F., Hougaard Bennekou, S., Kneuer, C., Ossendorp, B., Pedersen, R., Wolterink, G., & Mohimont, L. (2020). Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid. EFSA Journal, 18(4), Article e06088. https://doi.org/10.2903/j.efsa.2020.6088

A retrospective chronic cumulative risk assessment of dietary exposure to pesticide residues, supported by an uncertainty analysis based on expert knowledge elicitation, was conducted for two effects on the thyroid, hypothyroidism and parafollicular... Read More about Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid.

Cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system (2020)
Journal Article
Craig, P. S., Dujardin, B., Hart, A., Hernández‐Jerez, A. F., Hougaard Bennekou, S., Kneuer, C., Ossendorp, B., Pedersen, R., Wolterink, G., & Mohimont, L. (2020). Cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system. EFSA Journal, 18(4), Article e06087. https://doi.org/10.2903/j.efsa.2020.6087

A retrospective acute cumulative risk assessment of dietary exposure to pesticide residues, supported by an uncertainty analysis based on expert knowledge elicitation, was conducted for two effects on the nervous system: brain and/or erythrocyte acet... Read More about Cumulative dietary risk characterisation of pesticides that have acute effects on the nervous system.

Applicability of in silico tools for the prediction of dermal absorption for pesticides (2018)
Journal Article
Kneuer, C., Charistou, A., Craig, P., Eleftheriadou, D., Engel, N., Kjaerstad, M., Krishnan, S., Laskari, V., Machera, K., Nikolopoulou, D., Pieper, C., Schoen, E., Spilioti, E., & Buist, H. (2018). Applicability of in silico tools for the prediction of dermal absorption for pesticides. EFSA Supporting Publications, 15(10), Article 1493E. https://doi.org/10.2903/sp.efsa.2018.en-1493

Based on the “Human in vitro dermal absorption datasets” published as supporting information to the revised EFSA Guidance on Dermal Absorption, in silico models for prediction of absorption across the skin have been evaluated. For this evaluation, a... Read More about Applicability of in silico tools for the prediction of dermal absorption for pesticides.

The principles and methods behind EFSA's Guidance on Uncertainty Analysis in Scientific Assessment (2018)
Journal Article
Benford, D., Halldorsson, T., Jeger, M. J., Knutsen, H. K., More, S., Naegeli, H., …Hardy, A. (2018). The principles and methods behind EFSA's Guidance on Uncertainty Analysis in Scientific Assessment. EFSA Journal, 16(1), Article e05122. https://doi.org/10.2903/j.efsa.2018.5122

To meet the general requirement for transparency in EFSA's work, all its scientific assessments must consider uncertainty. Assessments must say clearly and unambiguously what sources of uncertainty have been identified and what is their impact on the... Read More about The principles and methods behind EFSA's Guidance on Uncertainty Analysis in Scientific Assessment.

Guidance on Uncertainty Analysis in Scientific Assessments (2018)
Journal Article
Benford, D., Halldorsson, T., Jeger, M. J., Knutsen, H. K., More, S., Naegeli, H., …Hardy, A. (2018). Guidance on Uncertainty Analysis in Scientific Assessments. EFSA Journal, 16(1), Article e05123. https://doi.org/10.2903/j.efsa.2018.5123

Uncertainty analysis is the process of identifying limitations in scientific knowledge and evaluating their implications for scientific conclusions. It is therefore relevant in all EFSA's scientific assessments and also necessary, to ensure that the... Read More about Guidance on Uncertainty Analysis in Scientific Assessments.

Fisher information under Gaussian quadrature models (2017)
Journal Article
Marques da Silva Júnior, A. H., Einbeck, J., & Craig, P. S. (2018). Fisher information under Gaussian quadrature models. Statistica Neerlandica, 72(2), 74-89. https://doi.org/10.1111/stan.12116

This paper develops formulae to compute the Fisher information matrix for the regression parameters of generalized linear models with Gaussian random effects. The Fisher information matrix relies on the estimation of the response variance under the m... Read More about Fisher information under Gaussian quadrature models.

Guidance on the use of the weight of evidence approach in scientific assessments (2017)
Journal Article
Hardy, A., Benford, D., Halldorsson, T., Jeger, M. J., Knutsen, H. K., More, S., …Younes, M. (2017). Guidance on the use of the weight of evidence approach in scientific assessments. EFSA Journal, 15(8), Article e04971. https://doi.org/10.2903/j.efsa.2017.4971

EFSA requested the Scientific Committee to develop a guidance document on the use of the weight of evidence approach in scientific assessments for use in all areas under EFSA's remit. The guidance document addresses the use of weight of evidence appr... Read More about Guidance on the use of the weight of evidence approach in scientific assessments.

Guidance on dermal absorption (2017)
Journal Article
Buist, H., Craig, P., Dewhurst, I., Hougaard Bennekou, S., Kneuer, C., Machera, K., …Chiusolo, A. (2017). Guidance on dermal absorption. EFSA Journal, 15(6), Article e04873. https://doi.org/10.2903/j.efsa.2017.4873

This guidance on the assessment of dermal absorption has been developed to assist notifiers, users of test facilities and Member State authorities on critical aspects related to the setting of dermal absorption values to be used in risk assessments o... Read More about Guidance on dermal absorption.

Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms (2017)
Journal Article
Ockleford, C., Adriaanse, P., Berny, P., Brock, T., Duquesne, S., Grilli, S., …Rob, S. (2017). Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms. EFSA Journal, 15(2), Article e04690. https://doi.org/10.2903/j.efsa.2017.4690

Following a request from EFSA, the Panel on Plant Protection Products and their Residues developed an opinion on the science behind the risk assessment of plant protection products for in-soil organisms. The current risk assessment scheme is reviewed... Read More about Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms.

Future needs and recommendations in the development of species sensitivity distributions: Estimating toxicity thresholds for aquatic ecological communities and assessing impacts of chemical exposures (2016)
Journal Article
Belanger, S., Barron, M., Craig, P., Dyer, S., Galay-Burgos, M., Hamer, M., …Whitehouse, P. (2016). Future needs and recommendations in the development of species sensitivity distributions: Estimating toxicity thresholds for aquatic ecological communities and assessing impacts of chemical exposures. Integrated Environmental Assessment and Management, 13(4), 664-674. https://doi.org/10.1002/ieam.1841

A species sensitivity distribution (SSD) is a probability model of the variation of species sensitivities to a stressor, in particular chemical exposure. The SSD approach has been used as a decision support tool in environmental protection and manage... Read More about Future needs and recommendations in the development of species sensitivity distributions: Estimating toxicity thresholds for aquatic ecological communities and assessing impacts of chemical exposures.

Gradient test for generalised linear models with random effects (2016)
Presentation / Conference Contribution
da Silva-Junior, A., Einbeck, J., & Craig, P. (2016, July). Gradient test for generalised linear models with random effects. Presented at International Workshop on Statistical Modelling, Rennes, France

This work develops the gradient test for parameter selection in generalised linear models with random effects. Asymptotically, the test statistic has a chi-squared distribution and the statistic has a compelling feature: it does not require computati... Read More about Gradient test for generalised linear models with random effects.

Hierarchical Emulation: a method for modeling and comparing nested simulators (2016)
Journal Article
Oughton, R. H., & Craig, P. S. (2016). Hierarchical Emulation: a method for modeling and comparing nested simulators. SIAM/ASA Journal on Uncertainty Quantification, 4(1), 495-519. https://doi.org/10.1137/15m1007914

Computer simulators often contain options to include extensions, leading to different versions of a particular simulator with slightly different input spaces. We develop hierarchical emulation, a method for emulating such simulators and for learning... Read More about Hierarchical Emulation: a method for modeling and comparing nested simulators.

Towards a landscape scale management of pesticides: ERA using changes in modelled occupancy and abundance to assess long-term population impacts of pesticides (2015)
Journal Article
Topping, C. J., Craig, P. S., de Jong, F., Klein, M., Laskowski, R., Manachini, B., …van der Linden, T. (2015). Towards a landscape scale management of pesticides: ERA using changes in modelled occupancy and abundance to assess long-term population impacts of pesticides. Science of the Total Environment, 537, 159-169. https://doi.org/10.1016/j.scitotenv.2015.07.152

Pesticides are regulated in Europe and this process includes an environmental risk assessment (ERA) for non-target arthropods (NTA). Traditionally a non-spatial or field trial assessment is used. In this study we exemplify the introduction of a spati... Read More about Towards a landscape scale management of pesticides: ERA using changes in modelled occupancy and abundance to assess long-term population impacts of pesticides.

Scientific Opinion addressing the state of the science on risk assessment of plant protection products for non-target arthropods (2015)
Journal Article
Aagaard, A., Brock, T., Capri, E., Duquesne, S., Filipic, M., Hernandez-Jerez, A., …Streissl, F. (2015). Scientific Opinion addressing the state of the science on risk assessment of plant protection products for non-target arthropods. EFSA Journal, 13(2), Article 3996. https://doi.org/10.2903/j.efsa.2015.3996

Following a request from the European Food Safety Authority, the Panel on Plant Protection Products and their Residues developed an opinion on the science to support the development of a risk assessment scheme of plant protection products for non-tar... Read More about Scientific Opinion addressing the state of the science on risk assessment of plant protection products for non-target arthropods.

Father absence and age at first birth in a western sample (2013)
Journal Article
Boothroyd, L., Craig, P., Crossman, R., & Perrett, D. (2013). Father absence and age at first birth in a western sample. American Journal of Human Biology, 25(3), 366-369. https://doi.org/10.1002/ajhb.22378

Objectives: Although a large literature has shown links between “father absence” during early childhood, and earlier puberty and sexual behavior in girls in Western populations, there are only a few studies which have looked at timing of reproduction... Read More about Father absence and age at first birth in a western sample.