David Parker's Outputs (13)

Synthesis of meta and para-substituted aromatic sulfonate derivatives of polydentate phenylazaphosphinate ligands: enhancement of the water solubility of emissive europium(III) EuroTracker® dyes (2014)
Journal Article
Delbianco, M., Lamarque, L., & Parker, D. (2014). Synthesis of meta and para-substituted aromatic sulfonate derivatives of polydentate phenylazaphosphinate ligands: enhancement of the water solubility of emissive europium(III) EuroTracker® dyes. Organic and Biomolecular Chemistry, 12(40), 8061-8071. https://doi.org/10.1039/c4ob01143k

The synthesis is described of a series of meta and para-substituted phenylsulfonate derivatives of very bright Eu(III) complexes with arylphosphinate groups and strongly absorbing arylalkynylpyridine moieties. The synthetic route involved the early i... Read More about Synthesis of meta and para-substituted aromatic sulfonate derivatives of polydentate phenylazaphosphinate ligands: enhancement of the water solubility of emissive europium(III) EuroTracker® dyes.

EuroTracker® dyes : design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging (2014)
Journal Article
Butler, S., Delbianco, M., Lamarque, L., McMahon, B., Neil, E., Pal, R., …Zwier, J. (2015). EuroTracker® dyes : design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging. Dalton Transactions, 44(11), 4791-4803. https://doi.org/10.1039/c4dt02785j

The development of the brightest luminescent europium(III) complexes is traced, including analysis of the C3-symmetric core complex based on a functionalized triazacyclononane and identification of the most suitable strongly absorbing chromophore. St... Read More about EuroTracker® dyes : design, synthesis, structure and photophysical properties of very bright europium complexes and their use in bioassays and cellular optical imaging.

Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo (2014)
Journal Article
Sim, N., Pal, R., Parker, D., Engelmann, J., Mishra, A., & Gottschalk, S. (2014). Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo. Organic and Biomolecular Chemistry, 12(46), 9389-9404. https://doi.org/10.1039/c4ob01848f

A second generation of N-methyl-D-aspartate (NMDA) receptor-targeted MRI contrast agents has been synthesised and evaluated in cellulo, based on established bicyclic NMDA receptor antagonists. Their use as responsive MR imaging probes has been evalua... Read More about Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo.

Bright, highly water soluble triazacyclononane europium complexes to detect ligand binding with time-resolved FRET microscopy (2014)
Journal Article
Delbianco, M., Sadovnikova, V., Bourrier, E., Mathis, G., Lamarque, L., Zwier, J., & Parker, D. (2014). Bright, highly water soluble triazacyclononane europium complexes to detect ligand binding with time-resolved FRET microscopy. Angewandte Chemie International Edition, 53(40), 10718-10722. https://doi.org/10.1002/anie.201406632

Luminescent europium complexes are used in a broad range of applications as a result of their particular emissive properties. The synthesis and application of bright, highly water-soluble, and negatively charged sulfonic- or carboxylic acid derivativ... Read More about Bright, highly water soluble triazacyclononane europium complexes to detect ligand binding with time-resolved FRET microscopy.

Selective ion pair recognition of citrate and zinc ions in water by ratiometric luminescence signaling (2014)
Journal Article
McMahon, B., & Parker, D. (2014). Selective ion pair recognition of citrate and zinc ions in water by ratiometric luminescence signaling. RSC Advances, 4(71), 37649-37654. https://doi.org/10.1039/c4ra07894b

Emission from a bright europium(III) complex, based on a 1,4,7-triazacyclononane ring bearing an alkyliminodiacetate group, is modulated only when in the presence of zinc(II) ions and a carboxylate anion and was characterised by ratiometric luminesce... Read More about Selective ion pair recognition of citrate and zinc ions in water by ratiometric luminescence signaling.

Comparative analysis of conjugated alkynyl chromophore-triazacyclononane ligands for sensitized emission of europium and terbium (2014)
Journal Article
Soulié, M., Latzko, F., Bourrier, E., Placide, V., Butler, S. J., Pal, R., …Maury, O. (2014). Comparative analysis of conjugated alkynyl chromophore-triazacyclononane ligands for sensitized emission of europium and terbium. Chemistry - A European Journal, 20(28), 8636 -8646. https://doi.org/10.1002/chem.201402415

A series of europium and terbium complexes based on a functionalized triazacyclononane carboxylate or phosphinate macrocyclic ligand is described. The influence of the anionic group, that is, carboxylate, methylphosphinate, or phenylphosphinate, on t... Read More about Comparative analysis of conjugated alkynyl chromophore-triazacyclononane ligands for sensitized emission of europium and terbium.

Synthesis, stereocontrol and structural studies of highly luminescent chiral tris-amidepyridyl-triazacyclononane lanthanide complexes (2014)
Journal Article
Neil, E. R., Funk, A. M., Yufit, D. S., & Parker, D. (2014). Synthesis, stereocontrol and structural studies of highly luminescent chiral tris-amidepyridyl-triazacyclononane lanthanide complexes. Dalton Transactions, 43(14), 5490-5504. https://doi.org/10.1039/c3dt53000k

The configuration of the remote amide chiral moiety determines the helicity of the metal complex in Ln(III) complexes of nonadentate N6O3 ligands based on triazacyclononane. Solution NMR studies revealed the presence of a dominant isomer whose propor... Read More about Synthesis, stereocontrol and structural studies of highly luminescent chiral tris-amidepyridyl-triazacyclononane lanthanide complexes.

Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes (2014)
Journal Article
Carr, R., Puckrin, R., McMahon, B. K., Pal, R., Parker, D., & Pålsson, L. (2014). Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes. Methods and Applications in Fluorescence, 2(2), Article 024007. https://doi.org/10.1088/2050-6120/2/2/024007

A circularly polarized luminescence (CPL) spectrometer has been built and used to study the binding interaction of lactate and four different proteins with racemic EuIII and TbIII complexes in aqueous solution. Lactate binding gives rise to strong in... Read More about Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes.

Critical analysis of the limitations of Bleaney's theory of magnetic anisotropy in paramagnetic lanthanide coordination complexes (2014)
Journal Article
Funk, A., Finney, K., Harvey, P., Kenwright, A., Neil, E., Rogers, N., …Parker, D. (2014). Critical analysis of the limitations of Bleaney's theory of magnetic anisotropy in paramagnetic lanthanide coordination complexes. Chemical Science, 6(3), 1655-1662. https://doi.org/10.1039/c4sc03429e

The origins of the breakdown of Bleaney's theory of magnetic anisotropy are described, based on an analysis of eleven different complexes of the second half of the 4f elements that form isostructural series. An examination of the chemical shift and r... Read More about Critical analysis of the limitations of Bleaney's theory of magnetic anisotropy in paramagnetic lanthanide coordination complexes.

Utility of tris(4-bromopyridyl) europium complexes as versatile intermediates in the divergent synthesis of emissive chiral probes (2014)
Journal Article
Butler, S. J., Delbianco, M., Evans, N. H., Frawley, A. T., Pal, R., Parker, D., …Yufit, D. S. (2014). Utility of tris(4-bromopyridyl) europium complexes as versatile intermediates in the divergent synthesis of emissive chiral probes. Dalton Transactions, 43(15), 5721-5730. https://doi.org/10.1039/c4dt00253a

The synthetic utility of europium complexes with three coordinated 4-bromopyridyl groups for chromophore elaboration has been assessed in palladium-catalysed Sonogashira coupling reactions, and in copper(I) mediated click reactions of the triazide de... Read More about Utility of tris(4-bromopyridyl) europium complexes as versatile intermediates in the divergent synthesis of emissive chiral probes.

Characterisation and evaluation of paramagnetic fluorine labelled glycol chitosan conjugates for 19F and 1H magnetic resonance imaging (2014)
Journal Article
De Luca, E., Harvey, P., Chalmers, K. H., Mishra, A. P., Senanayake, K., Wilson, J. I., …Parker, D. (2014). Characterisation and evaluation of paramagnetic fluorine labelled glycol chitosan conjugates for 19F and 1H magnetic resonance imaging. JBIC Journal of Biological Inorganic Chemistry, 19(2), 215-227. https://doi.org/10.1007/s00775-013-1028-y

Medium molecular weight glycol chitosan conjugates have been prepared, linked by an amide bond to paramagnetic Gd(III), Ho(III) and Dy(III) macrocyclic complexes in which a trifluoromethyl reporter group is located 6.5 Å from the paramagnetic centre.... Read More about Characterisation and evaluation of paramagnetic fluorine labelled glycol chitosan conjugates for 19F and 1H magnetic resonance imaging.

Emissive europium complexes that stain the cell walls of healthy plant cells, pollen tubes and roots (2014)
Journal Article
Palmer, A. J., Ford, S. H., Butler, S. J., Hawkins, T. J., Hussey, P. J., Pal, R., …Parker, D. (2014). Emissive europium complexes that stain the cell walls of healthy plant cells, pollen tubes and roots. RSC Advances, 4(18), 9356-9366. https://doi.org/10.1039/c3ra45426f

The cell-staining behaviour of a set of five emissive europium complexes has been studied in Nicotiana tabacum BY-2 cells and pollen tubes, Nicotiana benthamiana plant leaves and in the root hairs of the wild-type plant Arabidopsis thaliana (Columbia... Read More about Emissive europium complexes that stain the cell walls of healthy plant cells, pollen tubes and roots.

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging (2014)
Journal Article
Butler, S. J., Lamarque, L., Pal, R., & Parker, D. (2014). EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 2014(5), 1750-1756. https://doi.org/10.1039/c3sc53056f

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated... Read More about EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging.