EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

Butler, Stephen J.; Lamarque, Laurent; Pal, Robert; Parker, David

Abstract

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Citation

Butler, S. J., Lamarque, L., Pal, R., & Parker, D. (2014). EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging. Chemical Science, 2014(5), 1750-1756. https://doi.org/10.1039/c3sc53056f

• Journal Article Type: Article
• Acceptance Date: Dec 11, 2013
• Online Publication Date: Jan 27, 2014
• Publication Date: May 1, 2014
• Deposit Date: Jun 18, 2014
• Publicly Available Date: Dec 11, 2014
• Journal: Chemical Science
• Print ISSN: 2041-6520
• Electronic ISSN: 2041-6539
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 2014
• Issue: 5
• Pages: 1750-1756
• DOI: https://doi.org/10.1039/c3sc53056f
• Public URL: https://durham-repository.worktribe.com/output/1449816