Folate acts in E. coli to accelerate C. elegans aging independently of bacterial biosynthesis
(2016)
Journal Article
Virk, B., Jia, J., Maynard, C., Raimundo, A., Lefebvre, J., Richards, S., …Weinkove, D. (2016). Folate acts in E. coli to accelerate C. elegans aging independently of bacterial biosynthesis. Cell Reports, 14(7), 1611-1620. https://doi.org/10.1016/j.celrep.2016.01.051
Folates are cofactors for biosynthetic enzymes in all eukaryotic and prokaryotic cells. Animals cannot synthesize folate and must acquire it from their diet or microbiota. Previously, we showed that inhibiting E. coli folate synthesis increases C. el... Read More about Folate acts in E. coli to accelerate C. elegans aging independently of bacterial biosynthesis.