All Outputs (3)

Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa (2011)
Journal Article
Chadbourne, F., Raleigh, C., Ali, H., Denny, P., & Cobb, S. (2011). Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa. Journal of Peptide Science, 17(11), 751-755. https://doi.org/10.1002/psc.1398

Given the paucity and toxicity of available drugs for leishmaniasis, coupled with the advent of drug resistance, the discovery of new therapies for this neglected tropical disease is recognised as being of the utmost urgency. As such antimicrobial pe... Read More about Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa.

Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide. (2011)
Journal Article
Kong, H., Chadbourne, F., Law, G., Li, H., Tam, H., Cobb, S., …Wong, K. (2011). Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide. Chemical Communications, 47(28), 8052-8054. https://doi.org/10.1039/c1cc12811f

Responsive linear and two-photon induced europium emissive probes have been synthesised with a tailor made peptide for the detection of Cyclin A, the hypersensitive Eu emission (Eu-2) gave the real time signalling and also enhanced the two-photon abs... Read More about Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide..

Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks (2011)
Journal Article
Colgin, N., Flinn, T., & Cobb, S. (2011). Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks. Organic and Biomolecular Chemistry, 9(6), 1864-1870. https://doi.org/10.1039/c0ob00847h

Herein, we report the synthesis of novel phenylalanine and tyrosine derivatives containing a N-methyliminodiacetic acid boronate group. These compounds can be prepared enantiomerically pure, they are stable to column chromatography and they can be st... Read More about Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks.