N. Colgin
Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks
Colgin, N.; Flinn, T.; Cobb, S.L.
Abstract
Herein, we report the synthesis of novel phenylalanine and tyrosine derivatives containing a N-methyliminodiacetic acid boronate group. These compounds can be prepared enantiomerically pure, they are stable to column chromatography and they can be stored in air for two months without degradation occurring. This new class of boronate containing aromatic amino acids has potential applications in both peptide chemistry and natural product synthesis.
Citation
Colgin, N., Flinn, T., & Cobb, S. (2011). Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks. Organic and Biomolecular Chemistry, 9(6), 1864-1870. https://doi.org/10.1039/c0ob00847h
| Journal Article Type | Article |
|---|---|
| Publication Date | 2011-03 |
| Deposit Date | Feb 1, 2012 |
| Journal | Organic and Biomolecular Chemistry |
| Print ISSN | 1477-0520 |
| Electronic ISSN | 1477-0539 |
| Publisher | Royal Society of Chemistry |
| Peer Reviewed | Peer Reviewed |
| Volume | 9 |
| Issue | 6 |
| Pages | 1864-1870 |
| DOI | https://doi.org/10.1039/c0ob00847h |
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