Selective alkylation of mandelic acid to diarylacetic acids over a commercial zeolite

Meacham, Samuel G.; Taylor, Russell A.

Abstract

A commercial zeolite is shown to be a highly effective heterogeneous catalyst for the Friedel–Crafts alkyation of mandelic acid with aromatic substrates. The reaction yields mixed diarylacetic acids in one step avoiding the need for inert atmosphere techniques or superacids. The observed reaction pathways are zeolite framework dependent with only the FAU framework giving very high selectivity to the mixed diarylacetic acids.

Citation

Meacham, S. G., & Taylor, R. A. (2023). Selective alkylation of mandelic acid to diarylacetic acids over a commercial zeolite. Chemical Communications, 59(60), 9243-9246. https://doi.org/10.1039/d3cc01444d

• Journal Article Type: Article
• Acceptance Date: Jul 3, 2023
• Online Publication Date: Jul 6, 2023
• Publication Date: Aug 4, 2023
• Deposit Date: Sep 20, 2023
• Publicly Available Date: Sep 20, 2023
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 59
• Issue: 60
• Pages: 9243-9246
• DOI: https://doi.org/10.1039/d3cc01444d
• Keywords: Materials Chemistry; Metals and Alloys; Surfaces, Coatings and Films; General Chemistry; Ceramics and Composites; Electronic, Optical and Magnetic Materials; Catalysis
• Public URL: https://durham-repository.worktribe.com/output/1743887