Negative spatial association between lymphatic filariasis and malaria in West Africa.

Kelly-Hope, L.A; Diggle, P.J.; Rowlingson, B.S.; Gyapong, J.O.; Kyelem, D.; Coleman, M.; Thomson, M.C.; Obsomer, V.; Lindsay, S.W.; Hemingway, J.; Molyneux, D.H.

doi:10.1111/j.1365-3156.2005.01558.x

Negative spatial association between lymphatic filariasis and malaria in West Africa.

Kelly-Hope, L.A; Diggle, P.J.; Rowlingson, B.S.; Gyapong, J.O.; Kyelem, D.; Coleman, M.; Thomson, M.C.; Obsomer, V.; Lindsay, S.W.; Hemingway, J.; Molyneux, D.H.

Authors

L.A Kelly-Hope

P.J. Diggle

B.S. Rowlingson

J.O. Gyapong

D. Kyelem

M. Coleman

M.C. Thomson

V. Obsomer

Professor Steve Lindsay s.w.lindsay@durham.ac.uk
Professor

J. Hemingway

D.H. Molyneux

Abstract

Objective To determine the relationship between human lymphatic filariasis, caused by Wuchereria bancrofti, and falciparum malaria, which are co-endemic throughout West Africa. Methods We used geographical information systems and spatial statistics to examine the prevalence of lymphatic filariasis in relation to malaria prevalence, mosquito species distributions, vegetation and climate. Results A negative spatial association between W. bancrofti and falciparum malaria prevalence exists. Interspecies competition between parasites, seasonality, differences in the distribution and vector competence of Anopheles vectors, agricultural practices and insecticide resistance may be factors driving current (and potentially future) spatial distributions. Conclusion Further investigating these factors will become crucial as large-scale lymphatic filariasis and malaria control programmes are implemented in West Africa that may influence the epidemiology of both diseases.

Citation

Kelly-Hope, L., Diggle, P., Rowlingson, B., Gyapong, J., Kyelem, D., Coleman, M., …Molyneux, D. (2006). Negative spatial association between lymphatic filariasis and malaria in West Africa. Tropical Medicine and International Health, 11(2), 129-135. https://doi.org/10.1111/j.1365-3156.2005.01558.x

Journal Article Type	Article
Online Publication Date	Mar 30, 2006
Publication Date	2006-02
Journal	Tropical Medicine and International Health
Print ISSN	1360-2276
Electronic ISSN	1365-3156
Publisher	Wiley
Peer Reviewed	Peer Reviewed
Volume	11
Issue	2
Pages	129-135
DOI	https://doi.org/10.1111/j.1365-3156.2005.01558.x
Keywords	Anopheles;lymphatic filariasis;malaria;West Africa;epidemiology;transmission;climate;environment;geographical information systems;statistical modelling
Public URL	https://durham-repository.worktribe.com/output/1588106