B. Chakrabarti
Shear Unzipping of DNA
Chakrabarti, B.; Nelson, D.R.
Authors
D.R. Nelson
Abstract
We study theoretically the mechanical failure of a simple model of double-stranded DNA under an applied shear. Starting from a more microscopic Hamiltonian that describes a sheared DNA, we arrive at a nonlinear generalization of a ladder model of shear unzipping proposed earlier by deGennes [de Gennes, P. G. C. R. Acad. Sci., Ser. IV: Phys., Astrophys. 2001, 1505]. Using this model and a combination of analytical and numerical methods, we study the DNA “unzipping” transition when the shearing force exceeds a critical threshold at zero temperature. We also explore the effects of sequence heterogeneity and finite temperature and discuss possible applications to determine the strength of colloidal nanoparticle assemblies functionalized by DNA.
Citation
Chakrabarti, B., & Nelson, D. (2009). Shear Unzipping of DNA. Journal of Physical Chemistry B (Soft Condensed Matter and Biophysical Chemistry), 113(12), 3831-3836. https://doi.org/10.1021/jp808232p
Journal Article Type | Article |
---|---|
Publication Date | Mar 26, 2009 |
Deposit Date | Jan 20, 2015 |
Publicly Available Date | Jan 20, 2015 |
Journal | Journal of Physical Chemistry B (Soft Condensed Matter and Biophysical Chemistry) |
Print ISSN | 1520-6106 |
Electronic ISSN | 1520-5207 |
Publisher | American Chemical Society |
Peer Reviewed | Peer Reviewed |
Volume | 113 |
Issue | 12 |
Pages | 3831-3836 |
DOI | https://doi.org/10.1021/jp808232p |
Files
arXiv version
(293 Kb)
PDF
Copyright Statement
arXiv version
You might also like
Equilibrium of fluid membranes endowed with orientational order
(2017)
Journal Article
Elasticity dominated surface segregation of small molecules in polymer mixtures
(2016)
Journal Article
Downloadable Citations
About Durham Research Online (DRO)
Administrator e-mail: dro.admin@durham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search