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Spatial repellents: from discovery and development to evidence based validation

Achee, N.L.; Bangs, M.J.; Farlow, R.; Killeen, G.F.; Lindsay, S.W.; Logan, J.G.; Moore, S.J.; Rowland, M.; Sweeney, K.; Torr, S.J.; Zwiebel, L.J.; Grieco, J.P.

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N.L. Achee

M.J. Bangs

R. Farlow

G.F. Killeen

J.G. Logan

S.J. Moore

M. Rowland

K. Sweeney

S.J. Torr

L.J. Zwiebel

J.P. Grieco


International public health workers are challenged by a burden of arthropod-borne disease that remains elevated despite best efforts in control programmes. With this challenge comes the opportunity to develop novel vector control paradigms to guide product development and programme implementation. The role of vector behaviour modification in disease control was first highlighted several decades ago but has received limited attention within the public health community. This paper presents current evidence highlighting the value of sub-lethal agents, specifically spatial repellents, and their use in global health, and identifies the primary challenges towards establishing a clearly defined and recommended role for spatial repellent products in disease control.


Achee, N., Bangs, M., Farlow, R., Killeen, G., Lindsay, S., Logan, J., …Grieco, J. (2012). Spatial repellents: from discovery and development to evidence based validation. Malaria Journal, 11, Article 164.

Journal Article Type Article
Publication Date May 14, 2012
Deposit Date Jul 23, 2012
Publicly Available Date Jun 24, 2014
Journal Malaria Journal
Publisher BioMed Central
Peer Reviewed Peer Reviewed
Volume 11
Article Number 164
Keywords Public health, Spatial repellents, Vector control, Vector behaviour modification.


Published Journal Article (1.9 Mb)

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Copyright Statement
© 2012 Achee et al.; licensee BioMed Central Ltd. <br /> This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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