Framework for rapid assessment and adoption of new vector control tools

Vontas, J.; Moore, S.; Kleinschmidt, I.; Ranson, H.; Lindsay, S.W.; Lengeler, C.; Hamon, N.; McLean, T.; Hemingway, J.

Abstract

Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.

Citation

Vontas, J., Moore, S., Kleinschmidt, I., Ranson, H., Lindsay, S., Lengeler, C., …Hemingway, J. (2014). Framework for rapid assessment and adoption of new vector control tools. Trends in Parasitology, 30(4), 191-204. https://doi.org/10.1016/j.pt.2014.02.005

• Journal Article Type: Article
• Publication Date: Apr 1, 2014
• Deposit Date: May 6, 2014
• Journal: Trends in Parasitology
• Print ISSN: 1471-4922
• Publisher: Cell Press
• Peer Reviewed: Peer Reviewed
• Volume: 30
• Issue: 4
• Pages: 191-204
• DOI: https://doi.org/10.1016/j.pt.2014.02.005
• Keywords: Vectorial capacity, Vector control tool, Efficacy, Entomological parameters.
• Public URL: https://durham-repository.worktribe.com/output/1434262