Outputs (6)

The impact of circadian rhythms on medical imaging and radiotherapy regimes for the paediatric patient (2016)
Journal Article
Forssell-Aronsson, E., & Quinlan, R. (2017). The impact of circadian rhythms on medical imaging and radiotherapy regimes for the paediatric patient. Radiation Protection Dosimetry, 173(1-3), 16-20. https://doi.org/10.1093/rpd/ncw328

Daily rhythmic changes are found in cellular events in cell cycle, DNA repair, apoptosis and angiogenesis in both normal and tumour tissue, as well as in enzymatic activity and drug metabolism. In this paper, we hypothesize that circadian rhythms nee... Read More about The impact of circadian rhythms on medical imaging and radiotherapy regimes for the paediatric patient.

Biophysical dissection of schistosome septins: Insights into oligomerization and membrane binding (2016)
Journal Article
Zeraik, A., Staykova, M., Fontes, M., Nemuraitė, I., Quinlan, R., Araújo, A., & DeMarco, R. (2016). Biophysical dissection of schistosome septins: Insights into oligomerization and membrane binding. Biochimie, 131, 96-105. https://doi.org/10.1016/j.biochi.2016.09.014

Septins are GTP-binding proteins that are highly conserved among eukaryotes and which are usually membrane-associated. They have been linked to several critical cellular functions such as exocytosis and ciliogenesis, but little mechanistic detail is... Read More about Biophysical dissection of schistosome septins: Insights into oligomerization and membrane binding.

The Lipidation Profile of Aquaporin-0 Correlates with The Acyl Composition of Phosphoethanolamine Lipids in Lens Membranes (2016)
Journal Article
Ismail, V. S., Mosely, J. A., Tapodi, A., Quinlan, R. A., & Sanderson, J. M. (2016). The Lipidation Profile of Aquaporin-0 Correlates with The Acyl Composition of Phosphoethanolamine Lipids in Lens Membranes. BBA - Biomembranes, 1858(11), 2763-2768. https://doi.org/10.1016/j.bbamem.2016.06.026

The lens fiber major intrinsic protein (otherwise known as aquaporin-0 (AQP0), MIP26 and MP26) has been examined by mass spectrometry (MS) in order to determine the speciation of acyl modifications to the side chains of lysine residues and the N-term... Read More about The Lipidation Profile of Aquaporin-0 Correlates with The Acyl Composition of Phosphoethanolamine Lipids in Lens Membranes.

Sub-nanometre mapping of the aquaporin-water interface with multifrequency atomic force microscopy (2016)
Journal Article
Ricci, M., Quinlan, R., & Voïtchovsky, K. (2017). Sub-nanometre mapping of the aquaporin-water interface with multifrequency atomic force microscopy. Soft Matter, 13(1), 187-195. https://doi.org/10.1039/c6sm00751a

Aquaporins are integral membrane proteins that regulate the transport of water and small molecules in and out of the cell. In eye lens tissue, circulation of water, ions and metabolites is ensured by a microcirculation system in which aquaporin-0 (AQ... Read More about Sub-nanometre mapping of the aquaporin-water interface with multifrequency atomic force microscopy.

Small molecules, both dietary and endogenous, influence the onset of lens cataracts (2016)
Journal Article
Barnes, S., & Quinlan, R. (2016). Small molecules, both dietary and endogenous, influence the onset of lens cataracts. Experimental Eye Research, 156, 87-94. https://doi.org/10.1016/j.exer.2016.03.024

How the lens ages successfully is a lesson in biological adaption and the emergent properties of its complement of cells and proteins. This living tissue contains some of the oldest proteins in our bodies and yet they remain functional for decades, d... Read More about Small molecules, both dietary and endogenous, influence the onset of lens cataracts.

Radiation protection of the eye lens in medical workers—basis and impact of the ICRP recommendations (2016)
Journal Article
Barnard, S., Ainsbury, E., Quinlan, R., & Buffler, S. (2016). Radiation protection of the eye lens in medical workers—basis and impact of the ICRP recommendations. British Journal of Radiology, 89(1060), Article 20151034. https://doi.org/10.1259/bjr.20151034

The aim of this article was to explore the evidence for the revised European Union basic safety standard (BSS) radiation dose limits to the lens of the eye, in the context of medical occupational radiation exposures. Publications in the open literatu... Read More about Radiation protection of the eye lens in medical workers—basis and impact of the ICRP recommendations.