Outputs (1468)

Digital Banking—Building Atom bank’s Digital Twin (2025)
Book Chapter
Caiado, C. C., Huntley, N., & Twiddy, E. (2025). Digital Banking—Building Atom bank’s Digital Twin. In P. J. Aston (Ed.), More UK Success Stories in Industrial Mathematics (221-227). https://doi.org/10.1007/978-3-031-48683-8_28

Durham University worked in collaboration with Atom bank to develop an end-to-end banking model based on mathematical and statistical methods developed at Durham. The model provides the business with a strategic understanding of the relationships bet... Read More about Digital Banking—Building Atom bank’s Digital Twin.

Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work (2024)
Journal Article
Cramman, H., Arenas, B., Awais, R., Balaban, C., Cropper, C., Dennis, F., Finch, K., Gray, H., Hall, A., Kitchen, G., Norman, K., O’Driscoll, L., Petts, P., Petri, S., Robson, J., Rosenburgh, A., Shields, L., Swift, G. P., & Vaughan, H. (2024). Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work. Enhancing Teaching and Learning in Higher Education, 2, 39-69. https://doi.org/10.62512/etlhe.14

This paper presents the findings from a detailed study investigating UK undergraduate students’ experience of practical science in their post-16 studies during the COVID-19 pandemic. It also examines their perceived confidence and preparedness in rel... Read More about Post-16 students’ experience of practical science during the COVID-19 pandemic and the impact on students’ self-efficacy in practical work.

Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites. (2024)
Journal Article
Goncalves, K., & Przyborski, S. (2025). Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites. Neural Regeneration Research, 20(9), 2645-2654. https://doi.org/10.4103/NRR.NRR-D-23-01628

Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease. The accumulation of amyloid-β peptides, a key hallmark of Alzheimer's disease, is believed to induce neuritic abnormalitie... Read More about Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites..

Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. (2024)
Journal Article
Kelly, G., Kataura, T., Panek, J., Ma, G., Salmonowicz, H., Davis, A., Kendall, H., Brookes, C., Ayine-Tora, D. M., Banks, P., Nelson, G., Dobby, L., Pitrez, P. R., Booth, L., Costello, L., Richardson, G. D., Lovat, P., Przyborski, S., Ferreira, L., Greaves, L., …Korolchuk, V. I. (2024). Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule. Developmental Cell, 59(15), 1924-1939. https://doi.org/10.1016/j.devcel.2024.04.020

Selective degradation of damaged mitochondria by autophagy (mitophagy) is proposed to play an important role in cellular homeostasis. However, the molecular mechanisms and the requirement of mitochondrial quality control by mitophagy for cellular phy... Read More about Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule..

Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data (2024)
Journal Article
Garner, A., Preston, N., Caiado, C., Stubington, E., Hanratty, B., Limb, J., …Knight, J. (2024). Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data. BMC Geriatrics, 24(1), Article 449. https://doi.org/10.1186/s12877-024-05062-6

Background: Healthcare in care homes during the COVID-19 pandemic required a balance, providing treatment while minimising exposure risk. Policy for how residents should receive care changed rapidly throughout the pandemic. A lack of accessible data... Read More about Understanding health service utilisation patterns for care home residents during the COVID-19 pandemic using routinely collected healthcare data.

The impact of digital technology in care homes on unplanned secondary care usage and associated costs. (2024)
Journal Article
Garner, A., Lewis, J., Dixon, S., Preston, N., Caiado, C. C. S., Hanratty, B., …Mason, S. M. (2024). The impact of digital technology in care homes on unplanned secondary care usage and associated costs. Age and Ageing, 53(2), 1-7. https://doi.org/10.1093/ageing/afae004

Background
A substantial number of Emergency Department (ED) attendances by care home residents are potentially avoidable. Health Call Digital Care Homes is an app-based technology that aims to streamline residents’ care by recording their observati... Read More about The impact of digital technology in care homes on unplanned secondary care usage and associated costs..

Patterns Of Social Care Use Within The Older Population: What Can We Learn From Routinely Collected Data? (2023)
Presentation / Conference Contribution
Brotherhood, K., Hanratty, B., Spiers, G., Caiado, C., & Newton, J. (2023, November). Patterns Of Social Care Use Within The Older Population: What Can We Learn From Routinely Collected Data?. Presented at The GSA 2023 Annual Scientific Meeting, “Building Bridges > Catalyzing Research > Empowering All Ages”, Tampa, Florida

Research with routinely collected social care data has untapped potential to inform new care delivery approaches and techniques. To identify opportunities for service improvement and enhance our understanding of care pathways experienced by the older... Read More about Patterns Of Social Care Use Within The Older Population: What Can We Learn From Routinely Collected Data?.

Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications (2023)
Journal Article
Allcock, B., Wei, W., Goncalves, K., Hoyle, H., Robert, A., Quelch-Cliffe, R., …Przyborski, S. (2023). Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications. Cells, 12(19), Article 2408. https://doi.org/10.3390/cells12192408

It is widely recognised that cells respond to their microenvironment, which has implications for cell culture practices. Growth cues provided by 2D cell culture substrates are far removed from native 3D tissue structure in vivo. Geometry is one of ma... Read More about Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications.

Using deep learning to analyze the psychological effects of COVID-19 (2023)
Journal Article
Almeqren, M. A., Almegren, M., Alhayan, F., Cristea, A. I., & Pennington, D. R. (2023). Using deep learning to analyze the psychological effects of COVID-19. Frontiers in Psychology, 14, Article 962854. https://doi.org/10.3389/fpsyg.2023.962854

Problem: Sentiment Analysis (SA) automates the classification of the sentiment of people’s attitudes, feelings or reviews employing natural language processing (NLP) and computational approaches. Deep learning has recently demonstrated remarkable suc... Read More about Using deep learning to analyze the psychological effects of COVID-19.

The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation (2023)
Journal Article
Cristea, A. I., Alamri, A., Alshehri, M., Dwan Pereira, F., Toda, A. M., Harada T. de Oliveira, E., & Stewart, C. (2024). The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation. User Modeling and User-Adapted Interaction, 34(2), 323-374. https://doi.org/10.1007/s11257-023-09374-x

Massive Online Open Course (MOOC) platforms are considered a distinctive way to deliver a modern educational experience, open to a worldwide public. However, student engagement in MOOCs is a less explored area, although it is known that MOOCs suffer... Read More about The engage taxonomy: SDT-based measurable engagement indicators for MOOCs and their evaluation.