AO modal optimization in a live, beating zebrafish heart (2013)
Conference Proceeding
Bourgenot, C., Taylor, J. M., Saunter, C. D., Girkin, J. M., & Love, G. D. (2013). AO modal optimization in a live, beating zebrafish heart. . https://doi.org/10.1364/aopt.2013.ow4a.4

We report on the combinated use of heart synchronization and wavefront sensorless modal AO to enable significant improvement in image quality of a live transgenic zebrafish embryo heart, imaged with a light sheet microscope.

Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair (2013)
Journal Article
Matrone, G., Taylor, J. M., Wilson, K. S., Baily, J., Love, G. D., Girkin, J. M., …Denvir, M. A. (2013). Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair. International Journal of Cardiology, 168(4), 3913-3919. https://doi.org/10.1016/j.ijcard.2013.06.063

Background: While the adult zebrafish (Danio rerio) heart demonstrates a remarkable capacity for self-renewal following apical resection little is known about the response to injury in the embryonic heart. Methods: Injury to the beating zebrafish emb... Read More about Laser-targeted ablation of the zebrafish embryonic ventricle: A novel model of cardiac injury and repair.

An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets (2013)
Conference Proceeding
Hargreaves, A. L., Kirby, A. K., Bain, C. D., Love, G. D., Bolognesi, G., Ces, O., …Ward, A. D. (2013). An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets. In K. Dholakia, & G. C. Spalding (Eds.), . https://doi.org/10.1117/12.2027105

We discuss the design, implementation and performance of a novel platform for the production and optical control of ultra-low interfacial tension droplets in the 1-10 micron regime. A custom-designed, integrated microfluidic system allows the product... Read More about An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets.

Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy (2013)
Journal Article
Bourgenot, C., Saunter, C., Love, G., & Girkin, J. (2013). Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy. Journal of the European Optical Society-Rapid Publications, 8, Article 13027. https://doi.org/10.2971/jeos.2013.13027

We report on a closed loop widefield adaptive optics, optical microscopy system in which the feedback signal is provided by backscattered light from the sample acting as a guide star. The improvement in imaging performance is compared to an adaptive... Read More about Comparison of closed loop and sensorless adaptive optics in widefield optical microscopy.

Light sheet adaptive optics microscope for 3D live imaging (2013)
Conference Proceeding
Bourgenot, C., Taylor, J., Saunter, C., Girkin, J., & Love, G. (2013). Light sheet adaptive optics microscope for 3D live imaging. In C. J. Cogswell (Ed.), . https://doi.org/10.1117/12.2002057

We report on the incorporation of adaptive optics (AO) into the imaging arm of a selective plane illumination microscope (SPIM). SPIM has recently emerged as an important tool for life science research due to its ability to deliver high-speed, optica... Read More about Light sheet adaptive optics microscope for 3D live imaging.