Alexander L. Hargreaves
An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets
Hargreaves, Alexander L.; Kirby, Andrew K.; Bain, Colin D.; Love, Gordon D.; Bolognesi, Guido; Ces, Oscar; Neil, Mark; Ward, Andrew D.
Authors
Dr Andrew Kirby a.k.kirby@durham.ac.uk
Consultancy Work
Professor Colin Bain c.d.bain@durham.ac.uk
Pro-Vice-Chancellor (Research)
Gordon D. Love
Guido Bolognesi
Oscar Ces
Mark Neil
Andrew D. Ward
Contributors
Kishan Dholakia
Editor
Gabriel C. Spalding
Editor
Abstract
We discuss the design, implementation and performance of a novel platform for the production and optical control of ultra-low interfacial tension droplets in the 1-10 micron regime. A custom-designed, integrated microfluidic system allows the production of oil-in-water emulsion droplets of controllable size. This provides an optimised physical platform in which individual droplets are selected, trapped and shaped by holographic optical tweezers (HOTs) via extended optical landscaping. The 3D structure of the shaped droplet is interrogated by a combination of conventional brightfield imaging and fluorescent structured-illumination sectioning. We detail the problems and limitations of closed-loop holographic control of droplet shape.
Citation
Hargreaves, A. L., Kirby, A. K., Bain, C. D., Love, G. D., Bolognesi, G., Ces, O., …Ward, A. D. (2013). An optical platform for the production, trapping, manipulation and visualization of ultra-low interfacial tension emulsion droplets. In K. Dholakia, & G. C. Spalding (Eds.), . https://doi.org/10.1117/12.2027105
Presentation Conference Type | Conference Paper (Published) |
---|---|
Conference Name | Optical Trapping and Optical Micromanipulation X |
Start Date | Aug 25, 2013 |
End Date | Aug 29, 2013 |
Online Publication Date | Sep 12, 2013 |
Publication Date | 2013 |
Deposit Date | Apr 22, 2022 |
Publicly Available Date | Apr 22, 2022 |
Volume | 8810 |
Series ISSN | 0277-786X |
DOI | https://doi.org/10.1117/12.2027105 |
Public URL | https://durham-repository.worktribe.com/output/1137404 |
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Copyright Statement
Copyright 2013 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
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