The genetic landscape of crystallins in congenital cataract (2020)
Journal Article
Berry, V., Ionides, A., Pontikos, N., Georgiou, M., Yu, J., Ocaka, L. A., …Michaelides, M. (2020). The genetic landscape of crystallins in congenital cataract. Orphanet Journal of Rare Diseases, 15, Article 333. https://doi.org/10.1186/s13023-020-01613-3

Background: The crystalline lens is mainly composed of a large family of soluble proteins called the crystallins, which are responsible for its development, growth, transparency and refractive index. Disease-causing sequence variants in the crystalli... Read More about The genetic landscape of crystallins in congenital cataract.

Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description (2020)
Book Chapter
Scholle, M., Mellmann, M., Gaskell, P. H., Westerkamp, L., & Marner, F. (2020). Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description. In G. Ostermeyer, V. L. Popov, E. V. Shilko, & O. S. Vasiljeva (Eds.), Multiscale biomechanics and tribology of inorganic and organic system (359-375). Springer Verlag. https://doi.org/10.1007/978-3-030-60124-9_16

A first integral approach, derived in an analogous fashion to Maxwell’s use of potential fields, is employed to investigate the flow characteristics, with a view to minimising friction, of shear-driven fluid motion between rigid surfaces in parallel... Read More about Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description.

Suppressing Dimer Formation by Increasing Conformational Freedom in Multi-Carbazole Thermally Activated Delayed Fluorescence Emitters (2020)
Journal Article
Salah, L., Etherington, M., Shuaib, A., Danos, A., Nazeer, A., Ghazal, B., …Makhseed, S. (2021). Suppressing Dimer Formation by Increasing Conformational Freedom in Multi-Carbazole Thermally Activated Delayed Fluorescence Emitters. Journal of Materials Chemistry C Materials for optical and electronic devices, 9(1), 189-198. https://doi.org/10.1039/d0tc04222f

Ideal emitters for organic light-emitting diodes (OLEDs) are capable of efficiently harvesting non-emissive triplet states, have high colour stabilities, and possess high photoluminescence quantum yields (PLQYs). Maintaining colour stability and PLQY... Read More about Suppressing Dimer Formation by Increasing Conformational Freedom in Multi-Carbazole Thermally Activated Delayed Fluorescence Emitters.

Gold surface cleaning by etching polishing: Optimization of polycrystalline film topography and surface functionality for biosensing (2020)
Journal Article
Snopok, B., Laroussi, A., Cafolla, C., Voïtchovsky, K., Snopok, T., & Mirsky, V. M. (2021). Gold surface cleaning by etching polishing: Optimization of polycrystalline film topography and surface functionality for biosensing. Surfaces and Interfaces, 22, Article 100818. https://doi.org/10.1016/j.surfin.2020.100818

Modern bio-chemical sensors rely on functional interfacial architectures with well-defined structural nano-motifs over a physical transducer. Gold-coated interfaces are of particular interest for their desirable chemical (functionalization) and optic... Read More about Gold surface cleaning by etching polishing: Optimization of polycrystalline film topography and surface functionality for biosensing.

Explosivity of basaltic lava fountains is controlled by magma rheology, ascent rate and outgassing (2020)
Journal Article
La Spina, G., Arzilli, F., Llewellin, E., Burton, M., Clarke, A., de' Michieli Vitturi, M., …Mader, H. (2021). Explosivity of basaltic lava fountains is controlled by magma rheology, ascent rate and outgassing. Earth and Planetary Science Letters, 553, Article 116658. https://doi.org/10.1016/j.epsl.2020.116658

The dichotomy between explosive volcanic eruptions, which produce pyroclasts, and effusive eruptions, which produce lava, is defined by the presence or absence of fragmentation during magma ascent. For lava fountains the distinction is unclear, since... Read More about Explosivity of basaltic lava fountains is controlled by magma rheology, ascent rate and outgassing.

A model for permeability evolution during volcanic welding (2020)
Journal Article
Wadsworth, F. B., Vasseur, J., Llewellin, E. W., Brown, R. J., Tuffen, H., Gardner, J. E., …Marone, F. (2021). A model for permeability evolution during volcanic welding. Journal of Volcanology and Geothermal Research, 409, https://doi.org/10.1016/j.jvolgeores.2020.107118

Volcanic ash and pyroclasts can weld when deposited hot by pyroclastic density currents, in near-vent fall deposits, or in fractures in volcano interiors. Welding progressively decreases the permeability of the particle packs, influencing a range of... Read More about A model for permeability evolution during volcanic welding.

Aging in a mean field elastoplastic model of amorphous solids (2020)
Journal Article
Parley, J. T., Fielding, S. M., & Sollich, P. (2020). Aging in a mean field elastoplastic model of amorphous solids. Physics of Fluids, 32(12), Article 127104. https://doi.org/10.1063/5.0033196

We construct a mean-field elastoplastic description of the dynamics of amorphous solids under arbitrary time-dependent perturbations, building on the work of Lin and Wyart [Phys. Rev. X 6, 011005 (2016)] for steady shear. Local stresses are driven by... Read More about Aging in a mean field elastoplastic model of amorphous solids.

Predictive identification of co-formers in co-amorphous systems (2020)
Journal Article
Chambers, L. I., Grohganz, H., Palmelund, H., Löbmann, K., Rades, T., Musa, O. M., & Steed, J. W. (2021). Predictive identification of co-formers in co-amorphous systems. European Journal of Pharmaceutical Sciences, 157, Article 105636. https://doi.org/10.1016/j.ejps.2020.105636

This work aims to understand the properties of co-formers that form co-amorphous pharmaceutical materials and to predict co-amorphous system formation. A partial least square – discriminant analysis (PLS-DA) was performed using known co-amorphous sys... Read More about Predictive identification of co-formers in co-amorphous systems.

Tales of the unexpected. The non-random statistical copolymerisation of myrcene and styrene in the presence of a polar modifier’. (2020)
Journal Article
Shaw, L., & Hutchings, L. R. (in press). Tales of the unexpected. The non-random statistical copolymerisation of myrcene and styrene in the presence of a polar modifier’. Polymer Chemistry, https://doi.org/10.1039/d0py01099e

Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide (2020)
Journal Article
Saikia, B., Mulvee, M. T., Torres-Moya, I., Sarma, B., & Steed, J. W. (2020). Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide. Crystal Growth and Design, 20(12), 7989-7996. https://doi.org/10.1021/acs.cgd.0c01240

A strategic approach to control the polymorphism of two related drugs by introducing a drug-mimetic imide functional group into the molecular weight organogelator structure is presented. This was achieved with novel aminoglutethimide-derived bis(urea... Read More about Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide.

Convective tipping point initiates localization of basaltic fissure eruptions (2020)
Journal Article
Jones, T. J., & Llewellin, E. W. (2021). Convective tipping point initiates localization of basaltic fissure eruptions. Earth and Planetary Science Letters, 553, Article 116637. https://doi.org/10.1016/j.epsl.2020.116637

Basaltic fissure eruptions may evolve rapidly and unpredictably complicating hazard management. Localization of an elongate fissure to one or more focused vents may take days to months, and depends on fluid dynamic processes, such as thermally-driven... Read More about Convective tipping point initiates localization of basaltic fissure eruptions.

Ductile and Brittle Yielding in Thermal and Athermal Amorphous Materials (2020)
Journal Article
Barlow, H. J., Cochran, J. O., & Fielding, S. M. (2020). Ductile and Brittle Yielding in Thermal and Athermal Amorphous Materials. Physical Review Letters, 125(16), Article 168003. https://doi.org/10.1103/physrevlett.125.168003

We study theoretically the yielding of sheared amorphous materials as a function of increasing levels of initial sample annealing prior to shear, in three widely used constitutive models and three widely studied annealing protocols. In thermal system... Read More about Ductile and Brittle Yielding in Thermal and Athermal Amorphous Materials.

Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes and strain-dependent differences in epithelial cell organization (2020)
Journal Article
Kalligeraki, A. A., Isted, A., Pal, R., Saunter, C., Girkin, J., Jarrin, M., …Quinlan, R. A. (2020). Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes and strain-dependent differences in epithelial cell organization. Scientific Reports, 10, Article 16898. https://doi.org/10.1038/s41598-020-73625-9

Organ and tissue development are highly coordinated processes; lens growth and functional integration into the eye (emmetropia) is a robust example. An epithelial monolayer covers the anterior hemisphere of the lens, and its organization is the key t... Read More about Three-dimensional data capture and analysis of intact eye lenses evidences emmetropia-associated changes and strain-dependent differences in epithelial cell organization.

Explosive-effusive volcanic eruption transitions caused by sintering (2020)
Journal Article
Wadsworth, F. B., Llewellin, E. W., Vasseur, J., Gardner, J. E., & Tuffen, H. (2020). Explosive-effusive volcanic eruption transitions caused by sintering. Science Advances, 6(39), Article eaba7940. https://doi.org/10.1126/sciadv.aba7940

Silicic volcanic activity has long been framed as either violently explosive or gently effusive. However, recent observations demonstrate that explosive and effusive behavior can occur simultaneously. Here, we propose that rhyolitic magma feeding sub... Read More about Explosive-effusive volcanic eruption transitions caused by sintering.

Quantifying Microstructural Evolution in Moving Magma (2020)
Journal Article
Dobson, K. J., Allabar, A., Bretagne, E., Coumans, J., Cassidy, M., Cimarelli, C., …Wanelik, K. (2020). Quantifying Microstructural Evolution in Moving Magma. Frontiers in Earth Science, 8, https://doi.org/10.3389/feart.2020.00287

Many of the grand challenges in volcanic and magmatic research are focused on understanding the dynamics of highly heterogeneous systems and the critical conditions that enable magmas to move or eruptions to initiate. From the formation and developme... Read More about Quantifying Microstructural Evolution in Moving Magma.

Chain-stretch relaxation from low-frequency Fourier transform rheology (2020)
Journal Article
Reynolds, C., Hoyle, D., McLeish, T., & Thompson, R. (2020). Chain-stretch relaxation from low-frequency Fourier transform rheology. Physical Review Research, 2(3), Article 033457. https://doi.org/10.1103/physrevresearch.2.033457

Medium- or large-amplitude oscillatory shear (MAOS and LAOS, respectively) is sensitive to polymer chain structure, yet poses unsolved challenges for a priori structural characterization. We present a MAOS protocol applied to near-monodisperse linear... Read More about Chain-stretch relaxation from low-frequency Fourier transform rheology.

Bidirectional Motion of Droplets on Gradient Liquid Infused Surfaces (2020)
Journal Article
Sadullah, M. S., Launay, G., Parle, J., Ledesma-Aguilar, R., Gizaw, Y., McHale, G., …Kusumaatmaja, H. (2020). Bidirectional Motion of Droplets on Gradient Liquid Infused Surfaces. Communications Physics, 3, Article 166. https://doi.org/10.1038/s42005-020-00429-8

The current paradigm of self-propelled motion of liquid droplets on surfaces with chemical or topographical wetting gradients is always mono-directional. In contrast, here, we demonstrate bidirectional droplet motion, which we realize using liquid in... Read More about Bidirectional Motion of Droplets on Gradient Liquid Infused Surfaces.

Cylindrical Zwitterionic Particles via Interpolyelectrolyte Complexation on Molecular Polymer Brushes (2020)
Journal Article
Pelras, T., Nonappa, Mahon, C. S., & Müllner, M. (2021). Cylindrical Zwitterionic Particles via Interpolyelectrolyte Complexation on Molecular Polymer Brushes. Macromolecular Rapid Communications, 42(8), Article 2000401. https://doi.org/10.1002/marc.202000401

The fabrication of macromolecular architectures with high aspect ratio and well‐defined internal and external morphologies remains a challenge. The combination of template chemistry and self‐assembly concepts to construct peculiar polymer architectur... Read More about Cylindrical Zwitterionic Particles via Interpolyelectrolyte Complexation on Molecular Polymer Brushes.

Self-assembly and mesophase formation in a non-ionic chromonic liquid crystal: insights from bottom-up and top-down coarse-grained simulation models (2020)
Journal Article
Potter, T. D., Walker, M., & Wilson, M. R. (2020). Self-assembly and mesophase formation in a non-ionic chromonic liquid crystal: insights from bottom-up and top-down coarse-grained simulation models. Soft Matter, 16(41), 9488-9498. https://doi.org/10.1039/d0sm01157f

New coarse-grained models are introduced for a non-ionic chromonic molecule, TP6EO2M, in aqueous solution. The multiscale coarse-graining (MS-CG) approach is used, in the form of hybrid force matching (HFM), to produce a bottom-up CG model that demon... Read More about Self-assembly and mesophase formation in a non-ionic chromonic liquid crystal: insights from bottom-up and top-down coarse-grained simulation models.

Self-propelled droplet transport on shaped-liquid surfaces (2020)
Journal Article
Launay, G., Sadullah, M. S., McHale, G., Ledesma-Aguilar, R., Kusumaatmaja, H., & Wells, G. G. (2020). Self-propelled droplet transport on shaped-liquid surfaces. Scientific Reports, 10(14987), Article 14987. https://doi.org/10.1038/s41598-020-70988-x

The transport of small amounts of liquids on solid surfaces is fundamental for microfluidics applications. Technologies allowing control of droplets of liquid on flat surfaces generally involve the generation of a wettability contrast. This approach... Read More about Self-propelled droplet transport on shaped-liquid surfaces.