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Outputs (7)

Assessing the feasibility of the GOTT (Gabapentinoid and Opioid Tapering Toolkit) in a primary care setting in North-East England (2024)
Journal Article
Johnson, L., Cole, F., Kinchin, R., Francis, A., Winiarek, K., Hampshire, K., & Chazot, P. (online). Assessing the feasibility of the GOTT (Gabapentinoid and Opioid Tapering Toolkit) in a primary care setting in North-East England. British Journal of Pain, https://doi.org/10.1177/20494637241291534

To assess the feasibility and possible impacts of implementation of systematic non-pharmacological interventions to reduce the level of prescribing of opioid and gabapentinoid analgesics for chronic non-cancer pain (CNCP), particularly high-dose pres... Read More about Assessing the feasibility of the GOTT (Gabapentinoid and Opioid Tapering Toolkit) in a primary care setting in North-East England.

Rickets, resorption and revolution: An investigation into the relationship between vitamin D deficiency in childhood and osteoporosis in adulthood in an 18th-19th century population. (2024)
Journal Article
Bowers, A., Gowland, R., & Hind, K. (2024). Rickets, resorption and revolution: An investigation into the relationship between vitamin D deficiency in childhood and osteoporosis in adulthood in an 18th-19th century population. International Journal of Paleopathology, 47, 27-42. https://doi.org/10.1016/j.ijpp.2024.09.002

This study employs a Developmental Origins of Health and Disease (DOHaD) approach to assess the effect of vitamin D deficiency (VDD) in childhood on the risk of osteoporosis in adulthood in an archaeological sample of skeletons dating from the 18th t... Read More about Rickets, resorption and revolution: An investigation into the relationship between vitamin D deficiency in childhood and osteoporosis in adulthood in an 18th-19th century population..

Skeletal Loading: Lean and Bone Mass Development in Young Elite Male Gymnasts, Swimmers, and Nonathletes Aged 6-24 Years. (2024)
Journal Article
Gannon, L., & Hind, K. (online). Skeletal Loading: Lean and Bone Mass Development in Young Elite Male Gymnasts, Swimmers, and Nonathletes Aged 6-24 Years. Pediatric Exercise Science, https://doi.org/10.1123/pes.2024-0029

Exercise optimizes peak bone mass accrual, particularly if the loading is high magnitude and distributed in abnormal directions. Little is known about the influence of early intense training in sport during peak bone mass accrual, especially in boys.... Read More about Skeletal Loading: Lean and Bone Mass Development in Young Elite Male Gymnasts, Swimmers, and Nonathletes Aged 6-24 Years..

Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease (2024)
Journal Article
Escudier, O., Zhang, Y., Whiting, A., & Chazot, P. (2024). Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease. International Journal of Molecular Sciences, 25(18), Article 9764. https://doi.org/10.3390/ijms25189764

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease worldwide and is characterized by progressive muscle atrophy. There are currently two approved treatments, but they only relieve symptoms briefly and do not cure the disease.... Read More about Evaluation of a Synthetic Retinoid, Ellorarxine, in the NSC-34 Cell Model of Motor Neuron Disease.

Concussion-Related Biomarker Variations in Retired Rugby Players and Implications for Neurodegenerative Disease Risk: The UK Rugby Health Study (2024)
Journal Article
Alanazi, N., Fitzgerald, M., Hume, P., Hellewell, S., Horncastle, A., Anyaegbu, C., Papini, M. G., Hargreaves, N., Halicki, M., Entwistle, I., Hind, K., & Chazot, P. (2024). Concussion-Related Biomarker Variations in Retired Rugby Players and Implications for Neurodegenerative Disease Risk: The UK Rugby Health Study. International Journal of Molecular Sciences, 25(14), Article 7811. https://doi.org/10.3390/ijms25147811

The health and well-being of retired rugby union and league players, particularly regarding the long-term effects of concussions, are of major concern. Concussion has been identified as a major risk factor for neurodegenerative diseases, such as Alzh... Read More about Concussion-Related Biomarker Variations in Retired Rugby Players and Implications for Neurodegenerative Disease Risk: The UK Rugby Health Study.

Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions (2023)
Journal Article
Halicki, M. J., Hind, K., & Chazot, P. L. (2023). Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions. International Journal of Molecular Sciences, 24(16), Article 12556. https://doi.org/10.3390/ijms241612556

Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease consistently associated with repetitive traumatic brain injuries (TBIs), which makes multiple professions, such as contact sports athletes and the military, especially susceptible... Read More about Blood-Based Biomarkers in the Diagnosis of Chronic Traumatic Encephalopathy: Research to Date and Future Directions.

The Child of the North: Building a fairer future after COVID-19 (2021)
Report
Pickett, K., & Taylor-Robinson, D. (2021). The Child of the North: Building a fairer future after COVID-19. London: Northern Health Science Alliance and N8 Research Partnership

Children in the North are more likely to live in poverty than those in the rest of England – and increasingly so. Poverty is the lead driver of inequalities between children in the North and their counterparts in the rest of the country, leading to w... Read More about The Child of the North: Building a fairer future after COVID-19.