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Professor Steve Lindsay's Outputs (175)

Respiratory rates among rural Gambian children: a community-based cohort study (2024)
Journal Article
Mogeni, P., Amima, S., Gunther, J., Pinder, M., Tusting, L. S., D’Alessandro, U., Cousens, S., Lindsay, S. W., & Bradley, J. (2024). Respiratory rates among rural Gambian children: a community-based cohort study. Scientific Reports, 14(1), Article 20354. https://doi.org/10.1038/s41598-024-70796-7

Normal respiratory rates (RR) for children under five in the tropics are well-documented, but data for older children are limited. This study tracked RR changes with age and examined associations with nutritional status and environmental factors. We... Read More about Respiratory rates among rural Gambian children: a community-based cohort study.

The behaviour of adult Anopheles gambiae, sub-Saharan Africa’s principal malaria vector, and its relevance to malaria control: a review (2024)
Journal Article
Takken, W., Charlwood, D., & Lindsay, S. W. (2024). The behaviour of adult Anopheles gambiae, sub-Saharan Africa’s principal malaria vector, and its relevance to malaria control: a review. Malaria Journal, 23(1), Article 161. https://doi.org/10.1186/s12936-024-04982-3

Background: Mosquitoes of the Anopheles gambiae complex are one of the major vectors of malaria in sub-Saharan Africa. Their ability to transmit this disease of major public health importance is dependent on their abundance, biting behaviour, suscept... Read More about The behaviour of adult Anopheles gambiae, sub-Saharan Africa’s principal malaria vector, and its relevance to malaria control: a review.

The effect of physical barriers under a raised house on mosquito entry: an experimental study in rural Gambia (2024)
Journal Article
Carrasco-Tenezaca, M., Jawara, M., Bradley, J., D’Alessandro, U., Jeffries, D., Knudsen, J. B., & Lindsay, S. W. (2024). The effect of physical barriers under a raised house on mosquito entry: an experimental study in rural Gambia. Malaria Journal, 23, Article 100. https://doi.org/10.1186/s12936-024-04889-z

Background: Anopheles gambiae, the major malaria mosquito in sub-Saharan Africa, feed largely indoors at night. Raising a house off the ground with no barriers underneath reduces mosquito-house entry. This experiment tested whether walling off the sp... Read More about The effect of physical barriers under a raised house on mosquito entry: an experimental study in rural Gambia.

Effect of passive and active ventilation on malaria mosquito house entry and human comfort: an experimental study in rural Gambia (2023)
Journal Article
Carrasco-Tenezaca, M., Jawara, M., Lee, D. S., Holmes, M. S., Ceesay, S., McCall, P., …Wilson, A. L. (2023). Effect of passive and active ventilation on malaria mosquito house entry and human comfort: an experimental study in rural Gambia. Journal of the Royal Society. Interface, 20(201), https://doi.org/10.1098/rsif.2022.0794

Rural houses in sub-Saharan Africa are typically hot and allow malaria mosquitoes inside. We assessed whether passive or active ventilation can reduce house entry of malaria mosquitoes and cool a bedroom at night in rural Gambia. Two identical experi... Read More about Effect of passive and active ventilation on malaria mosquito house entry and human comfort: an experimental study in rural Gambia.

Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial (2022)
Journal Article
Soumare, H. M., Dabira, E. D., Camara, M. M., Jadama, L., Gaye, P. M., Kanteh, S., …D’Alessandro, U. (2022). Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial. Parasites and Vectors, 15(1), https://doi.org/10.1186/s13071-022-05557-4

Background Vector control interventions in sub-Saharan Africa rely on insecticide-treated nets and indoor residual spraying. Insecticide resistance, poor coverage of interventions, poor quality nets and changes in vector behavior threaten the effecti... Read More about Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial.

House screening for malaria control: views and experiences of participants in the RooPfs trial (2022)
Journal Article
Jones, C., Matta, A., Pinder, M., D’Alessandro, U., Knudsen, J., & Lindsay, S. W. (2022). House screening for malaria control: views and experiences of participants in the RooPfs trial. Malaria Journal, 21(294), https://doi.org/10.1186/s12936-022-04321-4

Background The housing stock of rural sub-Saharan Africa is changing rapidly. With millions of new homes required over the coming decades, there is an opportunity to protect residents by screening homes from malaria mosquitoes. This study, undertaken... Read More about House screening for malaria control: views and experiences of participants in the RooPfs trial.

Assessing the impact of a novel house design on the incidence of malaria in children in rural Africa: study protocol for a household-cluster randomized controlled superiority trial (2022)
Journal Article
Mshamu, S., Mmbando, A., Meta, J., Bradley, J., Bøjstrup, T. C., Day, N. P., …von Seidlein, L. (2022). Assessing the impact of a novel house design on the incidence of malaria in children in rural Africa: study protocol for a household-cluster randomized controlled superiority trial. Trials, 23(1), Article 519. https://doi.org/10.1186/s13063-022-06461-z

Background Traditional rural housing in hot, humid regions of sub-Saharan Africa usually consists of single-level, poorly ventilated dwellings. Houses are mostly poorly screened against malaria mosquitoes and limited airflow discourages the use of be... Read More about Assessing the impact of a novel house design on the incidence of malaria in children in rural Africa: study protocol for a household-cluster randomized controlled superiority trial.

Skin microbiome alters attractiveness to Anopheles mosquitoes (2022)
Journal Article
Showering, A., Martinez, J., Benavente, E. D., Gezan, S. A., Jones, R. T., Oke, C., …Logan, J. G. (2022). Skin microbiome alters attractiveness to Anopheles mosquitoes. BMC Microbiology, 22(1), https://doi.org/10.1186/s12866-022-02502-4

Background: Some people produce specifc body odours that make them more attractive than others to mosquitoes, and consequently are at higher risk of contracting vector-borne diseases. The skin microbiome can break down carbohydrates, fatty acids and... Read More about Skin microbiome alters attractiveness to Anopheles mosquitoes.

Using trained dogs and organic semi-conducting sensors to identify asymptomatic and mild SARS-CoV-2 infections: an observational study (2022)
Journal Article
Guest, C., Dewhirst, S. Y., Lindsay, S. W., Allen, D. J., Aziz, S., Baerenbold, O., …Davis, J. (2022). Using trained dogs and organic semi-conducting sensors to identify asymptomatic and mild SARS-CoV-2 infections: an observational study. Journal of Travel Medicine, 29(3), Article taac043. https://doi.org/10.1093/jtm/taac043

Background A rapid, accurate, non-invasive diagnostic screen is needed to identify people with SARS-CoV-2 infection. We investigated whether organic semi-conducting (OSC) sensors and trained dogs could distinguish between people infected with asympto... Read More about Using trained dogs and organic semi-conducting sensors to identify asymptomatic and mild SARS-CoV-2 infections: an observational study.

The durability, functionality and acceptability of novel screened doors and windows after 4 years of use in a Gambian village: a cross-sectional survey (2022)
Journal Article
Shenton, F. C., Jawara, M., Carrasco-Tenezaca, M., Knudsen, J., D’Alessandro, U., & Lindsay, S. W. (2022). The durability, functionality and acceptability of novel screened doors and windows after 4 years of use in a Gambian village: a cross-sectional survey. Malaria Journal, 21(1), https://doi.org/10.1186/s12936-022-04087-9

Background The World Health Organization recommends house screening as a tool for malaria control, yet evidence of the long-term durability, functionality and acceptability of this intervention is lacking. In this study, the sustainability and use of... Read More about The durability, functionality and acceptability of novel screened doors and windows after 4 years of use in a Gambian village: a cross-sectional survey.

The effect of light and ventilation on house entry by Anopheles arabiensis sampled using light traps in Tanzania: an experimental hut study (2022)
Journal Article
Mmbando, A. S., Bradley, J., Kazimbaya, D., Kasubiri, R., Knudsen, J., Siria, D., …Lindsay, S. W. (2022). The effect of light and ventilation on house entry by Anopheles arabiensis sampled using light traps in Tanzania: an experimental hut study. Malaria Journal, 21(1), https://doi.org/10.1186/s12936-022-04063-3

Background In sub-Saharan Africa, house design and ventilation affects the number of malaria mosquito vectors entering houses. This study hypothesized that indoor light from a CDC-light trap, visible from outside a hut, would increase entry of Anophe... Read More about The effect of light and ventilation on house entry by Anopheles arabiensis sampled using light traps in Tanzania: an experimental hut study.

Risk of Plasmodium falciparum infection in south-west Burkina Faso: potential impact of expanding eligibility for seasonal malaria chemoprevention (2022)
Journal Article
Yaro, J. B., Tiono, A. B., Ouedraogo, A., Lambert, B., Ouedraogo, Z. A., Diarra, A., …Wilson, A. L. (2022). Risk of Plasmodium falciparum infection in south-west Burkina Faso: potential impact of expanding eligibility for seasonal malaria chemoprevention. Scientific Reports, 12(1), Article 1402. https://doi.org/10.1038/s41598-022-05056-7

Burkina Faso has one of the highest malaria burdens in sub-Saharan Africa despite the mass deployment of insecticide-treated nets (ITNs) and use of seasonal malaria chemoprevention (SMC) in children aged up to 5 years. Identification of risk factors... Read More about Risk of Plasmodium falciparum infection in south-west Burkina Faso: potential impact of expanding eligibility for seasonal malaria chemoprevention.

Mass drug administration of ivermectin and dihydroartemisinin–piperaquine against malaria in settings with high coverage of standard control interventions: a cluster-randomised controlled trial in The Gambia (2021)
Journal Article
Dabira, E. D., Soumare, H. M., Conteh, B., Ceesay, F., Ndiath, M. O., Bradley, J., …D'Alessandro, U. (2022). Mass drug administration of ivermectin and dihydroartemisinin–piperaquine against malaria in settings with high coverage of standard control interventions: a cluster-randomised controlled trial in The Gambia. The Lancet Infectious Diseases, 22(4), 519-528. https://doi.org/10.1016/s1473-3099%2821%2900557-0

Background: Although the malaria burden has substantially decreased in sub-Saharan Africa, progress has stalled. We assessed whether mass administration of ivermectin (a mosquitocidal drug) and dihydroartemisinin–piperaquine (an antimalarial treatmen... Read More about Mass drug administration of ivermectin and dihydroartemisinin–piperaquine against malaria in settings with high coverage of standard control interventions: a cluster-randomised controlled trial in The Gambia.

Effect of roof colour on indoor temperature and human comfort levels, with implications for malaria control: a pilot study using experimental houses in rural Gambia (2021)
Journal Article
Carrasco-Tenezaca, M., Jatta, E., Jawara, M., Bradley, J., Pinder, M., D’Alessandro, U., …Lindsay, S. W. (2021). Effect of roof colour on indoor temperature and human comfort levels, with implications for malaria control: a pilot study using experimental houses in rural Gambia. Malaria Journal, 20(1), Article 423. https://doi.org/10.1186/s12936-021-03951-4

Background In rural sub-Saharan Africa, thatch roofs are being replaced by metal roofs. Metal roofing, however, increases indoor temperatures above human comfort levels, and thus makes it more likely that residents will not use an insecticide-treated... Read More about Effect of roof colour on indoor temperature and human comfort levels, with implications for malaria control: a pilot study using experimental houses in rural Gambia.

Estimating intervention effectiveness in trials of malaria interventions with contamination (2021)
Journal Article
Multerer, L., Vanobberghen, F., Glass, T. R., Hiscox, A., Lindsay, S. W., Takken, W., …Smith, T. (2021). Estimating intervention effectiveness in trials of malaria interventions with contamination. Malaria Journal, 20(1), Article 413. https://doi.org/10.1186/s12936-021-03924-7

Background: In cluster randomized trials (CRTs) or stepped wedge cluster randomized trials (SWCRTs) of malaria interventions, mosquito movement leads to contamination between trial arms unless bufer zones separate the clusters. Contamination can be a... Read More about Estimating intervention effectiveness in trials of malaria interventions with contamination.

Risk factors associated with house entry of malaria vectors in an area of Burkina Faso with high, persistent malaria transmission and high insecticide resistance (2021)
Journal Article
Yaro, J. B., Tiono, A. B., Sanou, A., Toe, H. K., Bradley, J., Ouedraogo, A., …Wilson, A. L. (2021). Risk factors associated with house entry of malaria vectors in an area of Burkina Faso with high, persistent malaria transmission and high insecticide resistance. Malaria Journal, 20(1), Article 397. https://doi.org/10.1186/s12936-021-03926-5

Background In rural Burkina Faso, the primary malaria vector Anopheles gambiae sensu lato (s.l.) primarily feeds indoors at night. Identification of factors which influence mosquito house entry could lead to development of novel malaria vector contro... Read More about Risk factors associated with house entry of malaria vectors in an area of Burkina Faso with high, persistent malaria transmission and high insecticide resistance.

Risk factors for Plasmodium falciparum infection in pregnant women in Burkina Faso: a community-based cross-sectional survey (2021)
Journal Article
Yaro, J. B., Ouedraogo, A., Diarra, A., Sombié, S., Ouedraogo, Z. A., Nébié, I., …Wilson, A. L. (2021). Risk factors for Plasmodium falciparum infection in pregnant women in Burkina Faso: a community-based cross-sectional survey. Malaria Journal, 20(1), Article 362. https://doi.org/10.1186/s12936-021-03896-8

Background: Malaria in pregnancy remains a public health problem in sub-Saharan Africa. Identifying risk factors for malaria in pregnancy could assist in developing interventions to reduce the risk of malaria in Burkina Faso and other countries in th... Read More about Risk factors for Plasmodium falciparum infection in pregnant women in Burkina Faso: a community-based cross-sectional survey.

Threats to the effectiveness of insecticide-treated bednets for malaria control: thinking beyond insecticide resistance (2021)
Journal Article
Lindsay, S. W., Thomas, M. B., & Kleinschmidt, I. (2021). Threats to the effectiveness of insecticide-treated bednets for malaria control: thinking beyond insecticide resistance. The Lancet Global Health, 9(9), e1325-e1331. https://doi.org/10.1016/s2214-109x%2821%2900216-3

From 2004 to 2019, insecticide-treated bednets (ITNs) have been the most effective tool for reducing malaria morbidity and mortality in sub-Saharan Africa. Recently, however, the decline in malaria cases and deaths has stalled. Some suggest that this... Read More about Threats to the effectiveness of insecticide-treated bednets for malaria control: thinking beyond insecticide resistance.

Pyriproxyfen-treated bed nets reduce reproductive fitness and longevity of pyrethroid-resistant Anopheles gambiae under laboratory and field conditions (2021)
Journal Article
Grisales, N., Lees, R. S., Maas, J., Morgan, J. C., Wangrawa, D. W., Guelbeogo, W. M., …Ranson, H. (2021). Pyriproxyfen-treated bed nets reduce reproductive fitness and longevity of pyrethroid-resistant Anopheles gambiae under laboratory and field conditions. Malaria Journal, 20(1), Article 273. https://doi.org/10.1186/s12936-021-03794-z

Background: The efficacy of insecticide-treated nets (ITNs) containing the insect growth regulator pyriproxyfen (PPF) and pyrethroid insecticides (PPF-ITNs) is being assessed in clinical trials to determine whether they provide greater protection fro... Read More about Pyriproxyfen-treated bed nets reduce reproductive fitness and longevity of pyrethroid-resistant Anopheles gambiae under laboratory and field conditions.

The relationship between house height and mosquito house entry: an experimental study in rural Gambia (2021)
Journal Article
Carrasco-Tenezaca, M., Jawara, M., Abdi, M. Y., Bradley, J., Brittain, O. S., Ceesay, S., …Lindsay, S. W. (2021). The relationship between house height and mosquito house entry: an experimental study in rural Gambia. Journal of the Royal Society. Interface, 18(178), Article 20210256. https://doi.org/10.1098/rsif.2021.0256

Most malaria infections in sub-Saharan Africa are acquired indoors, thus finding effective ways of preventing mosquito house entry should reduce transmission. Since most malaria mosquitoes fly less than 1 m from the ground, we tested whether raising... Read More about The relationship between house height and mosquito house entry: an experimental study in rural Gambia.

Impact of increased ventilation on indoor temperature and malaria mosquito density: an experimental study in The Gambia (2021)
Journal Article
Jatta, E., Carrasco-Tenezaca, M., Jawara, M., Bradley, J., Ceesay, S., D'Alessandro, U., …Lindsay, S. W. (2021). Impact of increased ventilation on indoor temperature and malaria mosquito density: an experimental study in The Gambia. Journal of the Royal Society. Interface, 18(178), Article 20201030. https://doi.org/10.1098/rsif.2020.1030

In sub-Saharan Africa, cooler houses would increase the coverage of insecticide-treated bednets, the primary malaria control tool. We examined whether improved ventilation, using windows screened with netting, cools houses at night and reduces malari... Read More about Impact of increased ventilation on indoor temperature and malaria mosquito density: an experimental study in The Gambia.

Improved housing versus usual practice for additional protection against clinical malaria in The Gambia (RooPfs): a household-randomised controlled trial (2021)
Journal Article
Pinder, M., Bradley, J., Jawara, M., Affara, M., Conteh, L., Correa, S., …Lindsay, S. W. (2021). Improved housing versus usual practice for additional protection against clinical malaria in The Gambia (RooPfs): a household-randomised controlled trial. The Lancet Planetary Health, 5(4), e220-e229. https://doi.org/10.1016/s2542-5196%2821%2900002-4

Background In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. We aimed to assess whether children in The Gambia received an incremental benefit from improved housing, where current best pra... Read More about Improved housing versus usual practice for additional protection against clinical malaria in The Gambia (RooPfs): a household-randomised controlled trial.

Preventing yellow fever epidemics in Asian megacities: how can cities control mosquito-transmitted diseases? (2021)
Journal Article
Shenton, F. C., & Lindsay, S. W. (2023). Preventing yellow fever epidemics in Asian megacities: how can cities control mosquito-transmitted diseases?. Cities and Health, 7(3), 335-341. https://doi.org/10.1080/23748834.2021.1899486

The COVID-19 pandemic has reminded us of the ever present threat from infectious diseases, this includes the ones we know about already and future unknowns. The mosquito-transmitted disease yellow fever has claimed thousands of lives over the centuri... Read More about Preventing yellow fever epidemics in Asian megacities: how can cities control mosquito-transmitted diseases?.

Impact of seasonality and malaria control interventions on Anopheles density and species composition from three areas of Uganda with differing malaria endemicity (2021)
Journal Article
Mawejje, H. D., Kilama, M., Kigozi, S. P., Musiime, A. K., Kamya, M., Lines, J., …Staedke, S. G. (2021). Impact of seasonality and malaria control interventions on Anopheles density and species composition from three areas of Uganda with differing malaria endemicity. Malaria Journal, 20, Article 138. https://doi.org/10.1186/s12936-021-03675-5

Background Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the malaria control interventions primarily responsible for reductions in transmission intensity across sub-Saharan Africa. These interventions, however, may hav... Read More about Impact of seasonality and malaria control interventions on Anopheles density and species composition from three areas of Uganda with differing malaria endemicity.

Recommendations for building out mosquito-transmitted diseases in sub-Saharan Africa: the DELIVER mnemonic (2020)
Journal Article
Lindsay, S. W., Davies, M., Alabaster, G., Altamirano, H., Jatta, E., Jawara, M., …Knudsen, J. (2021). Recommendations for building out mosquito-transmitted diseases in sub-Saharan Africa: the DELIVER mnemonic. Philosophical Transactions of the Royal Society B: Biological Sciences, 376(1818), Article 20190814. https://doi.org/10.1098/rstb.2019.0814

In sub-Saharan Africa, most transmission of mosquito-transmitted diseases, such as malaria or dengue, occurs within or around houses. Preventing mosquito house entry and reducing mosquito production around the home would help reduce the transmission... Read More about Recommendations for building out mosquito-transmitted diseases in sub-Saharan Africa: the DELIVER mnemonic.

A New Test of a Theory about Old Mosquitoes (2020)
Journal Article
Smith, D. L., Musiime, A. K., Maxwell, K., Lindsay, S. W., & Kiware, S. (2021). A New Test of a Theory about Old Mosquitoes. Trends in Parasitology, 37(3), 185-194. https://doi.org/10.1016/j.pt.2020.10.011

In vector control, it is widely accepted that killing adult mosquitoes would sharply reduce the proportion of old mosquitoes and cause the greatest changes to malaria transmission. The principle is based on a mathematical model of the sporozoite rate... Read More about A New Test of a Theory about Old Mosquitoes.

Mass Drug Administration With High-Dose Ivermectin and Dihydroartemisinin-Piperaquine for Malaria Elimination in an Area of Low Transmission With High Coverage of Malaria Control Interventions: Protocol for the MASSIV Cluster Randomized Clinical Trial (2020)
Journal Article
Dabira, E. D., Soumare, H. M., Lindsay, S. W., Conteh, B., Ceesay, F., Bradley, J., …D’Alessandro, U. (2020). Mass Drug Administration With High-Dose Ivermectin and Dihydroartemisinin-Piperaquine for Malaria Elimination in an Area of Low Transmission With High Coverage of Malaria Control Interventions: Protocol for the MASSIV Cluster Randomized Clinical Trial. JMIR Research Protocols, 9(11), Article e20904. https://doi.org/10.2196/20904

Background: With a decline in malaria burden, innovative interventions and tools are required to reduce malaria transmission further. Mass drug administration (MDA) of artemisinin-based combination therapy (ACT) has been identified as a potential too... Read More about Mass Drug Administration With High-Dose Ivermectin and Dihydroartemisinin-Piperaquine for Malaria Elimination in an Area of Low Transmission With High Coverage of Malaria Control Interventions: Protocol for the MASSIV Cluster Randomized Clinical Trial.

Old age is associated with decreased wealth in rural villages in Mtwara, Tanzania: findings from a cross‐sectional survey (2020)
Journal Article
Mshamu, S., Peerawaranun, P., Kahabuka, C., Deen, J., Tusting, L., Lindsay, S. W., …von Seidlein, L. (2020). Old age is associated with decreased wealth in rural villages in Mtwara, Tanzania: findings from a cross‐sectional survey. Tropical Medicine and International Health, 25(12), 1441-1449. https://doi.org/10.1111/tmi.13496

Objective: In many countries housing is used for wealth accumulation and provides financial security in old age. We tested the hypothesis that household wealth, measured by housing quality and ownership of durable assets, would increase with age of t... Read More about Old age is associated with decreased wealth in rural villages in Mtwara, Tanzania: findings from a cross‐sectional survey.

A cohort study to identify risk factors for Plasmodium falciparum infection in Burkinabe children: implications for other high burden high impact countries (2020)
Journal Article
Yaro, J. B., Ouedraogo, A., Ouedraogo, Z. A., Diarra, A., Lankouande, M., Agboraw, E., …Wilson, A. L. (2020). A cohort study to identify risk factors for Plasmodium falciparum infection in Burkinabe children: implications for other high burden high impact countries. Malaria Journal, 19(1), Article 371. https://doi.org/10.1186/s12936-020-03443-x

Background: Progress in controlling malaria has stalled in recent years. Today the malaria burden is increasingly concentrated in a few countries, including Burkina Faso, where malaria is not declining. A cohort study was conducted to identify risk f... Read More about A cohort study to identify risk factors for Plasmodium falciparum infection in Burkinabe children: implications for other high burden high impact countries.

A greener vision for vector control: The example of the Singapore dengue control programme (2020)
Journal Article
Sim, S., Ng, L. C., Lindsay, S. W., & Wilson, A. L. (2020). A greener vision for vector control: The example of the Singapore dengue control programme. PLoS Neglected Tropical Diseases, 14(8), Article e0008428. https://doi.org/10.1371/journal.pntd.0008428

Vector-borne diseases are a major cause of morbidity and mortality worldwide. Aedes-borne diseases, in particular, including dengue, chikungunya, yellow fever, and Zika, are increasing at an alarming rate due to urbanisation, population movement, wea... Read More about A greener vision for vector control: The example of the Singapore dengue control programme.

Vector bionomics and vectorial capacity as emergent properties of mosquito behaviors and ecology (2020)
Journal Article
Wu, S. L., Sánchez C., H. M., Henry, J. M., Citron, D. T., Zhang, Q., Compton, K., …Smith, D. L. (2020). Vector bionomics and vectorial capacity as emergent properties of mosquito behaviors and ecology. PLoS Computational Biology, 16(4), Article e1007446. https://doi.org/10.1371/journal.pcbi.1007446

Mosquitoes are important vectors for pathogens that infect humans and other vertebrate animals. Some aspects of adult mosquito behavior and mosquito ecology play an important role in determining the capacity of vector populations to transmit pathogen... Read More about Vector bionomics and vectorial capacity as emergent properties of mosquito behaviors and ecology.

Modelling geospatial distributions of the triatomine vectors of Trypanosoma cruzi in Latin America (2020)
Journal Article
Bender, A., Python, A., Lindsay, S. W., Golding, N., & Moyes, C. L. (2020). Modelling geospatial distributions of the triatomine vectors of Trypanosoma cruzi in Latin America. PLoS Neglected Tropical Diseases, 14(8), Article e0008411. https://doi.org/10.1371/journal.pntd.0008411

Approximately 150 triatomine species are suspected to be infected with the Chagas parasite, Trypanosoma cruzi, but they differ in the risk they pose to human populations. The largest risk comes from species that have a domestic life cycle and these s... Read More about Modelling geospatial distributions of the triatomine vectors of Trypanosoma cruzi in Latin America.

Measuring ventilation in different typologies of rural Gambian houses: a pilot experimental study (2020)
Journal Article
Knudsen, J. B., Pinder, M., Jatta, E., Jawara, M., Yousuf, M. A., Søndergaard, A. T., & Lindsay, S. W. (2020). Measuring ventilation in different typologies of rural Gambian houses: a pilot experimental study. Malaria Journal, 19(1), Article 273. https://doi.org/10.1186/s12936-020-03327-0

Background: African houses are frequently too hot and uncomfortable to use a bed net at night. Indoor thermal comfort is often evaluated by measuring temperature and humidity, ignoring ventilation. This study explored ways to measure ventilation in s... Read More about Measuring ventilation in different typologies of rural Gambian houses: a pilot experimental study.

Evidence of high bed net usage from a list randomization experiments in rural Gambia (2020)
Journal Article
Brew, J., Pinder, M., D’Alessandro, U., Lindsay, S. W., Jones, C., & Sicuri, E. (2020). Evidence of high bed net usage from a list randomization experiments in rural Gambia. Malaria Journal, 19(1), Article 248. https://doi.org/10.1186/s12936-020-03322-5

Background: Recording behaviours that have the potential to impact health can be doubly challenging if the behaviour takes place in private spaces that cannot be observed directly, and where respondents answer what they think the recorder may want to... Read More about Evidence of high bed net usage from a list randomization experiments in rural Gambia.

Identification and characterization of immature Anopheles and culicines (Diptera: Culicidae) at three sites of varying malaria transmission intensities in Uganda (2020)
Journal Article
Musiime, A. K., Smith, D. L., Kilama, M., Geoffrey, O., Kyagamba, P., Rek, J., …Lindsay, S. W. (2020). Identification and characterization of immature Anopheles and culicines (Diptera: Culicidae) at three sites of varying malaria transmission intensities in Uganda. Malaria Journal, 19(1), https://doi.org/10.1186/s12936-020-03304-7

Background: Over the last two decades, there has been remarkable progress in malaria control in sub-Saharan Africa, due mainly to the massive deployment of long-lasting insecticidal nets and indoor residual spraying. Despite these gains, it is clear... Read More about Identification and characterization of immature Anopheles and culicines (Diptera: Culicidae) at three sites of varying malaria transmission intensities in Uganda.

Environmental temperature and growth faltering in African children: a cross-sectional study (2020)
Journal Article
Tusting, L. S., Bradley, J., Bhatt, S., Gibson, H. S., Weiss, D. J., Shenton, F. C., & Lindsay, S. W. (2020). Environmental temperature and growth faltering in African children: a cross-sectional study. The Lancet Planetary Health, 4(3), e116-e123. https://doi.org/10.1016/s2542-5196%2820%2930037-1

Background: Child growth faltering persists in sub-Saharan Africa despite the scale-up of nutrition, water, and sanitation interventions over the past 2 decades. High temperatures have been hypothesised to contribute to child growth faltering via an... Read More about Environmental temperature and growth faltering in African children: a cross-sectional study.

Housing and child health in sub-Saharan Africa: A cross-sectional analysis (2020)
Journal Article
Tusting, L. S., Gething, P. W., Gibson, H. S., Greenwood, B., Knudsen, J., Lindsay, S. W., & Bhatt, S. (2020). Housing and child health in sub-Saharan Africa: A cross-sectional analysis. PLoS Medicine, 17(3), Article e1003055. https://doi.org/10.1371/journal.pmed.1003055

Background: Housing is essential to human well-being but neglected in global health. Today, housing in Africa is rapidly improving alongside economic development, creating an urgent need to understand how these changes can benefit health. We hypothes... Read More about Housing and child health in sub-Saharan Africa: A cross-sectional analysis.

Responses of the putative trachoma vector, Musca sorbens, to volatile semiochemicals from human faeces (2020)
Journal Article
Robinson, A., Bristow, J., Holl, M. V., Makalo, P., Alemayehu, W., Bailey, R. L., …Logan, J. G. (2020). Responses of the putative trachoma vector, Musca sorbens, to volatile semiochemicals from human faeces. PLoS Neglected Tropical Diseases, 14(3), Article e0007719. https://doi.org/10.1371/journal.pntd.0007719

The putative vector of trachoma, Musca sorbens, prefers to lay its eggs on human faeces on the ground. This study sought to determine whether M. sorbens females were attracted to volatile odours from human faeces in preference to odours from the faec... Read More about Responses of the putative trachoma vector, Musca sorbens, to volatile semiochemicals from human faeces.

The importance of vector control for the control and elimination of vector-borne diseases (2020)
Journal Article
Wilson, A. L., Courtenay, O., Kelly-Hope, L. A., Scott, T. W., Takken, W., Torr, S. J., & Lindsay, S. W. (2020). The importance of vector control for the control and elimination of vector-borne diseases. PLoS Neglected Tropical Diseases, 14(1), Article e0007831. https://doi.org/10.1371/journal.pntd.0007831

Vector-borne diseases (VBDs) such as malaria, dengue, and leishmaniasis exert a huge burden of morbidity and mortality worldwide, particularly affecting the poorest of the poor. The principal method by which these diseases are controlled is through v... Read More about The importance of vector control for the control and elimination of vector-borne diseases.

Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions (2020)
Journal Article
Ahmed, A., Dietrich, I., LaBeaud, A. D., Lindsay, S. W., Musa, A., & Weaver, S. C. (2020). Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions. Viruses, 12(1), Article 81. https://doi.org/10.3390/v12010081

The risk of emergence and/or re-emergence of arthropod-borne viral (arboviral) infections is rapidly growing worldwide, particularly in Africa. The burden of arboviral infections and diseases is not well scrutinized because of the inefficient surveil... Read More about Risks and Challenges of Arboviral Diseases in Sudan: The Urgent Need for Actions.

Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda (2019)
Journal Article
Musiime, A. K., Smith, D. L., Kilama, M., Rek, J., Arinaitwe, E., Nankabirwa, J. I., …Egonyu, J. P. (2019). Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda. Malaria Journal, 18(1), Article 445. https://doi.org/10.1186/s12936-019-3076-4

Background Long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are widely recommended for the prevention of malaria in endemic regions. Data from human landing catches provide information on the impact of vector c... Read More about Impact of vector control interventions on malaria transmission intensity, outdoor vector biting rates and Anopheles mosquito species composition in Tororo, Uganda.

Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial (2019)
Journal Article
Toé, K. H., Mechan, F., Tangena, J. A., Morris, M., Solino, J., Tchicaya, E. F., …Sagnon, N. (2019). Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial. Malaria Journal, 18, Article 383. https://doi.org/10.1186/s12936-019-3018-1

Background Long-lasting insecticidal nets (LLINs) treated with pyrethroids are the foundation of malaria control in sub-Saharan Africa. Rising pyrethroid resistance in vectors, however, has driven the development of alternative net formulations. Here... Read More about Assessing the impact of the addition of pyriproxyfen on the durability of permethrin-treated bed nets in Burkina Faso: a compound-randomized controlled trial.

Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa (2019)
Journal Article
Shenton, F. C., Addissie, A., Alabaster, G., Baziwe, D., Carrasco Tenezaca, M., Chinula, D., …Lindsay, S. W. (2022). Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa. Cities and Health, 6(1), 72-80. https://doi.org/10.1080/23748834.2019.1684771

Mosquito-transmitted diseases are a major threat to health in sub-Saharan Africa, but could be reduced through modifications to the built environment. Here we report findings from a major workshop held to identify the research gaps in this area, name... Read More about Research agenda for preventing mosquito-transmitted diseases through improving the built environment in sub-Saharan Africa.

Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control (2019)
Journal Article
Mbare, O., Lindsay, S. W., & Fillinger, U. (2019). Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control. BMC Infectious Diseases, 19(1), Article 800. https://doi.org/10.1186/s12879-019-4438-9

Background Larviciding is an effective supplementary tool for malaria vector control, but the identification and accessibility of aquatic habitats impedes application. Dissemination of the insect growth regulator, pyriproxyfen (PPF), by gravid Anophe... Read More about Testing a pyriproxyfen auto-dissemination station attractive to gravid Anopheles gambiae sensu stricto for the development of a novel attract-release -and-kill strategy for malaria vector control.

Pareto rules for malaria super-spreaders and super-spreading (2019)
Journal Article
Cooper, L., Kang, S. Y., Bisanzio, D., Maxwell, K., Rodriguez-Barraquer, I., Greenhouse, B., …Smith, D. L. (2019). Pareto rules for malaria super-spreaders and super-spreading. Nature Communications, 10(1), Article 3939. https://doi.org/10.1038/s41467-019-11861-y

Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An 80-20 “Pareto” rule has been proposed to describe this heterogeneity whereby 80% of transmission is accounted for by 20% of individuals, herein called super-... Read More about Pareto rules for malaria super-spreaders and super-spreading.

Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa (2019)
Journal Article
Takken, W., & Lindsay, S. (2019). Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa. Emerging Infectious Diseases, 25(7), 1431-1432. https://doi.org/10.3201/eid2507.190301

Malaria continues to be a major health threat in Africa, mainly in rural areas. Recently, the urban malaria vector Anopheles stephensi invaded Djibouti and Ethiopia, potentially spreading to other areas of Africa. Urgent action is needed to prevent u... Read More about Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa.

Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa (2019)
Journal Article
Lindsay, S. W., Jawara, M., Mwesigwa, J., Achan, J., Bayoh, N., Bradley, J., …D’Alessandro, U. (2019). Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa. Scientific Reports, 9(1), Article 7770. https://doi.org/10.1038/s41598-019-43816-0

In The Gambia, metal-roof houses were hotter during the day than thatched-roof houses. After 24 h, the mortality of Anopheles gambiae, the principal African malaria vector, was 38% higher in metal-roof houses than thatched ones. During the day, mosqu... Read More about Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa.

Mapping changes in housing in sub-Saharan Africa from 2000 to 2015 (2019)
Journal Article
Tusting, L. S., Bisanzio, D., Alabaster, G., Cameron, E., Cibulskis, R., Davies, M., …Bhatt, S. (2019). Mapping changes in housing in sub-Saharan Africa from 2000 to 2015. Nature, 568, 391-394. https://doi.org/10.1038/s41586-019-1050-5

Access to adequate housing is a fundamental human right, essential to human security, nutrition and health, and a core objective of the United Nations Sustainable Development Goals1,2. Globally, the housing need is most acute in Africa, where the pop... Read More about Mapping changes in housing in sub-Saharan Africa from 2000 to 2015.

Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa (2019)
Journal Article
Kasstan, B., Hampshire, K., Guest, C., Logan, J., Pinder, M., Williams, K., …Lindsay, S. (2019). Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa. Journal of Biosocial Science, 51(3), 436-436-443. https://doi.org/10.1017/s0021932018000408

Bio-Detection Dogs (BDDs) are used in some high-income countries as a diagnostic intervention, yet little is known about their potential in low/middle-income countries with limited diagnostic resources. This exploratory study investigated the opportu... Read More about Sniff and tell: the feasibility of using bio-detection dogs as a mobile diagnostic intervention for asymptomatic malaria in sub-Saharan Africa.

Field evaluation of personal protection methods against outdoor-biting mosquitoes in Lao PDR (2018)
Journal Article
Tangena, J. A., Thammavong, P., Chonephetsarath, S., Logan, J. G., Brey, P. T., & Lindsay, S. W. (2018). Field evaluation of personal protection methods against outdoor-biting mosquitoes in Lao PDR. Parasites and Vectors, 11(1), Article 661. https://doi.org/10.1186/s13071-018-3239-0

Background: Protecting people outdoors against mosquito-borne diseases is a major challenge. Here we compared commercially available personal protection methods to identify the most effective method for outdoor use in northern Lao PDR. Methods: From... Read More about Field evaluation of personal protection methods against outdoor-biting mosquitoes in Lao PDR.

Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda (2018)
Journal Article
Kang, S. Y., Battle, K. E., Gibson, H. S., Cooper, L. V., Maxwell, K., Kamya, M., …Bisanzio, D. (2018). Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda. Gates Open Research, 2, Article 32. https://doi.org/10.12688/gatesopenres.12838.2

Background: Heterogeneity in malaria transmission has household, temporal, and spatial components. These factors are relevant for improving the efficiency of malaria control by targeting heterogeneity. To quantify variation, we analyzed mosquito coun... Read More about Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda.

How house design affects malaria mosquito density, temperature, and relative humidity: an experimental study in rural Gambia (2018)
Journal Article
Jatta, E., Jawara, M., Bradley, J., Jeffries, D., Kandeh, B., Knudsen, J. B., …Lindsay, S. W. (2018). How house design affects malaria mosquito density, temperature, and relative humidity: an experimental study in rural Gambia. The Lancet Planetary Health, 2(11), e498-e508. https://doi.org/10.1016/s2542-5196%2818%2930234-1

Introduction: Unprecedented improvements in housing are occurring across much of rural sub-Saharan Africa, but the consequences of these changes on malaria transmission remain poorly explored. We examined how different typologies of rural housing aff... Read More about How house design affects malaria mosquito density, temperature, and relative humidity: an experimental study in rural Gambia.

Bionomics and insecticide resistance of the arboviral vector Aedes albopictus in northern Lao PDR (2018)
Journal Article
Tangena, J. A., Marcombe, S., Thammavong, P., Chonephetsarath, S., Somphong, B., Sayteng, K., …Brey, P. T. (2018). Bionomics and insecticide resistance of the arboviral vector Aedes albopictus in northern Lao PDR. PLoS ONE, 13(10), Article e0206387. https://doi.org/10.1371/journal.pone.0206387

In the last four decades there has been a staggering increase in the geographical range of the arboviral vector Aedes albopictus (Skuse, 1894). This species is now found in every continent except Antarctica, increasing the distribution of arboviral d... Read More about Bionomics and insecticide resistance of the arboviral vector Aedes albopictus in northern Lao PDR.

New Prototype Screened Doors and Windows for Excluding Mosquitoes from Houses: A Pilot Study in Rural Gambia (2018)
Journal Article
Jawara, M., Bell, D., D’Alessandro, U., Hunt, V., Jones, C., Pinder, M., …Kandeh, B. (2018). New Prototype Screened Doors and Windows for Excluding Mosquitoes from Houses: A Pilot Study in Rural Gambia. American Journal of Tropical Medicine and Hygiene, 99(6), 1475-1484. https://doi.org/10.4269/ajtmh.18-0660

Despite compelling evidence that modern housing protects against malaria, houses in endemic areas are still commonly porous to mosquitoes. The protective efficacy of four prototype screened doors and two windows designs against mosquito house entry,... Read More about New Prototype Screened Doors and Windows for Excluding Mosquitoes from Houses: A Pilot Study in Rural Gambia.

Revisiting an old idea: engineering against vector-borne diseases in the domestic environment (2018)
Journal Article
Wilson, A., Davies, M., & Lindsay, S. (2019). Revisiting an old idea: engineering against vector-borne diseases in the domestic environment. Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(2), 53-55. https://doi.org/10.1093/trstmh/try103

On 21 April 1983 the Royal Society of Tropical Medicine and Hygiene held a joint meeting with the Institute of Civil Engineers at Manson House on ‘Engineering against Insect-borne Diseases in the Domestic Environment’. The summary of a talk by Chris... Read More about Revisiting an old idea: engineering against vector-borne diseases in the domestic environment.

Bird-biting mosquitoes on farms in southern England (2018)
Journal Article
Brugman, V. A., Medlock, J. M., Logan, J. G., Wilson, A. J., Lindsay, S. W., Fooks, A. R., …Carpenter, S. T. (2018). Bird-biting mosquitoes on farms in southern England. Veterinary Record, 183, Article 474. https://doi.org/10.1136/vr.104830

Mosquitoes that blood-feed on avian hosts are important vectors of many arthropod-borne viruses (arboviruses). In Europe, these include West Nile virus (WNV), Usutu virus (USUTV) and Sindbis virus. These are all maintained in enzootic bird-mosquito-b... Read More about Bird-biting mosquitoes on farms in southern England.

Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial (2018)
Journal Article
Tiono, A. B., Ouédraogo, A., Ouattara, D., Bougouma, E. C., Coulibaly, S., Diarra, A., …Lindsay, S. W. (2018). Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial. The Lancet, 392(10147), 569-580. https://doi.org/10.1016/s0140-6736%2818%2931711-2

Background Substantial reductions in malaria incidence in sub-Saharan Africa have been achieved with massive deployment of long-lasting insecticidal nets (LLINs), but pyrethroid resistance threatens control. Burkina Faso is an area with intense malar... Read More about Efficacy of Olyset Duo, a bednet containing pyriproxyfen and permethrin, versus a permethrin-only net against clinical malaria in an area with highly pyrethroid-resistant vectors in rural Burkina Faso: a cluster-randomised controlled trial.

Is chronic malnutrition associated with an increase in malaria incidence? A cohort study in children aged under 5 years in rural Gambia (2018)
Journal Article
Wilson, A., Bradley, J., Kandeh, B., Salami, K., D’Alessandro, U., Pinder, M., & Lindsay, S. (2018). Is chronic malnutrition associated with an increase in malaria incidence? A cohort study in children aged under 5 years in rural Gambia. Parasites and Vectors, 11, Article 451. https://doi.org/10.1186/s13071-018-3026-y

Background Malnutrition is common in children in sub-Saharan Africa and is thought to increase the risk of infectious diseases, including malaria. The relationship between malnutrition and malaria was examined in a cohort of 6–59 month-old children i... Read More about Is chronic malnutrition associated with an increase in malaria incidence? A cohort study in children aged under 5 years in rural Gambia.

Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group † (2018)
Journal Article
James, S., Godfray, H. C. J., Lindsay, S. W., Welkhoff, P. A., Savadogo, M., Touré, Y. T., …Singh, J. A. (2018). Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group †. American Journal of Tropical Medicine and Hygiene, 98(6_Suppl), 1-49. https://doi.org/10.4269/ajtmh.18-0083

Gene drive technology offers the promise for a high-impact, cost-effective, and durable method to control malaria transmission that would make a significant contribution to elimination. Gene drive systems, such as those based on clustered regularly i... Read More about Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group †.

Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children (2018)
Journal Article
Wilson, A., Pinder, M., Bradley, J., Donnelly, M., Hamid-Adiamoh, M., Jarju, L., …Lindsay, S. (2018). Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children. Malaria Journal, 17, Article 205. https://doi.org/10.1186/s12936-018-2348-8

Background Insecticide resistance threatens malaria control in sub-Saharan Africa. Knockdown resistance to pyrethroids and organochlorines in Anopheles gambiae sensu lato (s.l.) is commonly caused by mutations in the gene encoding a voltage-gated sod... Read More about Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children.

Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial (2018)
Journal Article
Staedke, S. G., Maiteki-Sebuguzi, C., Rehman, A. M., Kigozi, S. P., Gonahasa, S., Okiring, J., …Drakeley, C. (2018). Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial. The Lancet Global Health, 6(6), e668-e679. https://doi.org/10.1016/s2214-109x%2818%2930126-8

Background Intermittent preventive treatment (IPT) is a well established malaria control intervention. Evidence that delivering IPT to schoolchildren could provide community-level benefits is limited. We did a cluster-randomised controlled trial to a... Read More about Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial.

Rapid improvements to rural Ugandan housing and their association with malaria from intense to reduced transmission: a cohort study (2018)
Journal Article
Rek, J. C., Alegana, V., Arinaitwe, E., Cameron, E., Kamya, M. R., Katureebe, A., …Tusting, L. S. (2018). Rapid improvements to rural Ugandan housing and their association with malaria from intense to reduced transmission: a cohort study. The Lancet Planetary Health, 2(2), e83-e94. https://doi.org/10.1016/s2542-5196%2818%2930010-x

Background Rapid population growth in Africa requires an urgent expansion and improvement of housing options. Improving housing presents a promising opportunity for malaria control by reducing indoor exposure to mosquitoes. We measured recent changes... Read More about Rapid improvements to rural Ugandan housing and their association with malaria from intense to reduced transmission: a cohort study.

Residual malaria transmission dynamics varies across The Gambia despite high coverage of control interventions (2017)
Journal Article
Mwesigwa, J., Achan, J., Di Tanna, G. L., Affara, M., Jawara, M., Worwui, A., …D’Alessandro, U. (2017). Residual malaria transmission dynamics varies across The Gambia despite high coverage of control interventions. PLoS ONE, 12(11), Article e0187059. https://doi.org/10.1371/journal.pone.0187059

Over the last decades, malaria has declined substantially in The Gambia but its transmission has not been interrupted. In order to better target control interventions, it is essential to understand the dynamics of residual transmission. This prospect... Read More about Residual malaria transmission dynamics varies across The Gambia despite high coverage of control interventions.

Affordable house designs to improve health in rural Africa: a field study from northeastern Tanzania (2017)
Journal Article
Von Seidlein, L., Ikonomedis, K., Mshamu, S., Nkya, T., Mukaka, M., Pell, C., …Knudsen, J. (2017). Affordable house designs to improve health in rural Africa: a field study from northeastern Tanzania. The Lancet Planetary Health, 1(5), e188-e199. https://doi.org/10.1016/s2542-5196%2817%2930078-5

Background The population of sub-Saharan Africa is currently estimated to be 1245 million and is expected to quadruple by the end of the century, necessitating the building of millions of homes. Malaria remains a substantial problem in this region an... Read More about Affordable house designs to improve health in rural Africa: a field study from northeastern Tanzania.

Risk of exposure to potential vector mosquitoes for rural workers in Northern Lao PDR (2017)
Journal Article
Tangena, J. A., Thammavong, P., Lindsay, S. W., & Brey, P. T. (2017). Risk of exposure to potential vector mosquitoes for rural workers in Northern Lao PDR. PLoS Neglected Tropical Diseases, 11(7), Article e0005802. https://doi.org/10.1371/journal.pntd.0005802

Background One major consequence of economic development in South-East Asia has been a rapid expansion of rubber plantations, in which outbreaks of dengue and malaria have occurred. Here we explored the difference in risk of exposure to potential den... Read More about Risk of exposure to potential vector mosquitoes for rural workers in Northern Lao PDR.

Diversity of Mosquitoes (Diptera: Culicidae) Attracted to Human Subjects in Rubber Plantations, Secondary Forests, and Villages in Luang Prabang Province, Northern Lao PDR (2017)
Journal Article
Tangena, J. A., Thammavong, P., Malaithong, N., Inthavong, T., Ouanesamon, P., Brey, P. T., & Lindsay, S. W. (2017). Diversity of Mosquitoes (Diptera: Culicidae) Attracted to Human Subjects in Rubber Plantations, Secondary Forests, and Villages in Luang Prabang Province, Northern Lao PDR. Journal of Medical Entomology, 54(6), 1589-1604. https://doi.org/10.1093/jme/tjx071

The impact of the rapid expansion of rubber plantations in South-East Asia on mosquito populations is uncertain. We compared the abundance and diversity of adult mosquitoes using human-baited traps in four typical rural habitats in northern Lao PDR:... Read More about Diversity of Mosquitoes (Diptera: Culicidae) Attracted to Human Subjects in Rubber Plantations, Secondary Forests, and Villages in Luang Prabang Province, Northern Lao PDR.

The contemporary distribution of Trypanosoma cruzi infection in humans, alternative hosts and vectors (2017)
Journal Article
Browne, A., Guerra, C., Alves, R., Costa, V., Wilson, A., Pigott, D., …Moyes, C. (2017). The contemporary distribution of Trypanosoma cruzi infection in humans, alternative hosts and vectors. Scientific Data, 4, Article 170050. https://doi.org/10.1038/sdata.2017.50

Chagas is a potentially fatal chronic disease affecting large numbers of people across the Americas and exported throughout the world through human population movement. It is caused by the Trypanosoma cruzi parasite, which is transmitted by triatomin... Read More about The contemporary distribution of Trypanosoma cruzi infection in humans, alternative hosts and vectors.

Resurgence of malaria after discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda (2017)
Journal Article
Raouf, S., Mpimbaza, A., Kigozi, R., Sserwanga, A., Rubahika, D., Katamba, H., …Dorsey, G. (2017). Resurgence of malaria after discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda. The Lancet Global Health, 4(1), https://doi.org/10.1016/s2214-109x%2816%2930014-6

Background: In 2009, Uganda implemented a programme of indoor residual spraying of insecticide (IRS) in ten districts in the Northern Region with historically high malaria transmission intensity. This programme was successful in reducing the burden o... Read More about Resurgence of malaria after discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda.

The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals (2017)
Journal Article
Bangert, M., Molyneux, D. H., Lindsay, S. W., Fitzpatrick, C., & Engels, D. (2017). The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals. Infectious Diseases of Poverty, 6(1), Article 73. https://doi.org/10.1186/s40249-017-0288-0

The Sustainable Development Goals (SDGs) call for an integrated response, the kind that has defined Neglected Tropical Diseases (NTDs) efforts in the past decade. NTD interventions have the greatest relevance for SDG3, the health goal, where the focu... Read More about The cross-cutting contribution of the end of neglected tropical diseases to the sustainable development goals.

Resurgence of malaria following discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda (2017)
Journal Article
Raouf, S., Mpimbaza, A., Kigozi, R., Sserwanga, A., Rubahike, A., Katamba, H., …Dorsey, G. (2017). Resurgence of malaria following discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda. Clinical Infectious Diseases, 65(3), 453-460. https://doi.org/10.1093/cid/cix251

Background Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) are the primary tools for malaria prevention in Africa. It is not known whether reductions in malaria can be sustained after IRS is discontinued. The aim of this stu... Read More about Resurgence of malaria following discontinuation of indoor residual spraying of insecticide in a previously high transmission intensity area of Uganda.

Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data (2017)
Journal Article
Tusting, L., Bottomley, C., Gibson, H., Kleinschmidt, I., Tatem, A., Lindsay, S., & Gething, P. (2017). Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data. PLoS Medicine, 14(2), Article e1002234. https://doi.org/10.1371/journal.pmed.1002234

Improvements to housing may contribute to malaria control and elimination by reducing house entry by malaria vectors and thus exposure to biting. We tested the hypothesis that the odds of malaria infection are lower in modern, improved housing compar... Read More about Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data.

Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western Kenya (2017)
Journal Article
Njoroge, M., Tirados, I., Lindsay, S., Vale, G., Torr, S., & Fillinger, U. (2017). Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western Kenya. Parasites and Vectors, 10(1), Article 18. https://doi.org/10.1186/s13071-016-1957-8

Background Malaria vector mosquitoes with exophilic and zoophilic tendencies, or with a high acceptance of alternative blood meal sources when preferred human blood-hosts are unavailable, may help maintain low but constant malaria transmission in are... Read More about Exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western Kenya.

Spatio-temporal analysis of malaria vector density from baseline through intervention in a high transmission setting (2016)
Journal Article
Alegana, V., Kigozi, S., Nankabirwa, J., Arinaitwe, E., Kigozi, R., Mawejje, H., …Tatem, A. (2016). Spatio-temporal analysis of malaria vector density from baseline through intervention in a high transmission setting. Parasites and Vectors, 9(1), Article 637. https://doi.org/10.1186/s13071-016-1917-3

Background: An increase in effective malaria control since 2000 has contributed to a decline in global malaria morbidity and mortality. Knowing when and how existing interventions could be combined to maximise their impact on malaria vectors can prov... Read More about Spatio-temporal analysis of malaria vector density from baseline through intervention in a high transmission setting.

Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study (2016)
Journal Article
Katureebe, A., Zinszer, K., Arinaitwe, E., Rek, J., Kakande, E., Charland, K., …Dorsey, G. (2016). Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study. PLoS Medicine, 13(11), Article e1002167. https://doi.org/10.1371/journal.pmed.1002167

Background Long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are the primary vector control interventions used to prevent malaria in Africa. Although both interventions are effective in some settings, high-quali... Read More about Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study.

Why is malaria associated with poverty? Findings from a cohort study in rural Uganda (2016)
Journal Article
Tusting, L., Rek, J., Arinaitwe, E., Staedke, S., Kamya, M., Cano, J., …Lines, J. (2016). Why is malaria associated with poverty? Findings from a cohort study in rural Uganda. Infectious Diseases of Poverty, 5(1), Article 78. https://doi.org/10.1186/s40249-016-0164-3

Background Malaria control and sustainable development are linked, but implementation of ‘multisectoral’ intervention is restricted by a limited understanding of the causal pathways between poverty and malaria. We investigated the relationships betwe... Read More about Why is malaria associated with poverty? Findings from a cohort study in rural Uganda.

The RooPfs study to assess whether improved housing provides additional protection against clinical malaria over current best practice in The Gambia: study protocol for a randomized controlled study and ancillary studies (2016)
Journal Article
Pinder, M., Conteh, L., Jeffries, D., Jones, C., Knudsen, J., Kandeh, B., …Lindsay, S. (2016). The RooPfs study to assess whether improved housing provides additional protection against clinical malaria over current best practice in The Gambia: study protocol for a randomized controlled study and ancillary studies. Trials, 17(1), Article 275. https://doi.org/10.1186/s13063-016-1400-7

Background In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. This study will determine if modern housing provides incremental protection against clinical malaria over the current best prac... Read More about The RooPfs study to assess whether improved housing provides additional protection against clinical malaria over current best practice in The Gambia: study protocol for a randomized controlled study and ancillary studies.

Personal protection of permethrin-treated clothing against Aedes aegypti, the vector of dengue and Zika virus, in the laboratory (2016)
Journal Article
Orsborne, J., DeRaedt Banks, S., Hendy, A., Gezan, S., Kaur, H., Wilder-Smith, A., …Logan, J. (2016). Personal protection of permethrin-treated clothing against Aedes aegypti, the vector of dengue and Zika virus, in the laboratory. PLoS ONE, 11(5), Article e0152805. https://doi.org/10.1371/journal.pone.0152805

Background The dengue and Zika viruses are primarily transmitted by Aedes aegypti mosquitoes, which are most active during day light hours and feed both in and outside of the household. Personal protection technologies such as insecticide-treated clo... Read More about Personal protection of permethrin-treated clothing against Aedes aegypti, the vector of dengue and Zika virus, in the laboratory.

Field evaluation of two novel sampling devices for collecting wild oviposition site seeking malaria vector mosquitoes: OviART gravid traps and squares of electrocuting nets (2016)
Journal Article
Dugassa, S., Lindh, J., Lindsay, S., & Fillinger, U. (2016). Field evaluation of two novel sampling devices for collecting wild oviposition site seeking malaria vector mosquitoes: OviART gravid traps and squares of electrocuting nets. Parasites and Vectors, 9, Article 272. https://doi.org/10.1186/s13071-016-1557-7

Background: New sampling tools are needed for collecting exophilic malaria mosquitoes in sub-Saharan Africa to monitor the impact of vector control interventions. The OviART gravid trap and squares of electrocuting nets (e-nets) were recently develop... Read More about Field evaluation of two novel sampling devices for collecting wild oviposition site seeking malaria vector mosquitoes: OviART gravid traps and squares of electrocuting nets.

Can the buck always be passed to the highest level of clustering? (2016)
Journal Article
Bottomley, C., Kirby, M., Lindsay, S., & Alexander, N. (2016). Can the buck always be passed to the highest level of clustering?. BMC Medical Research Methodology, 16(1), Article 29. https://doi.org/10.1186/s12874-016-0127-1

Background: Clustering commonly affects the uncertainty of parameter estimates in epidemiological studies. Cluster-robust variance estimates (CRVE) are used to construct confidence intervals that account for single-level clustering, and are easily im... Read More about Can the buck always be passed to the highest level of clustering?.

Risk and Control of Mosquito-Borne Diseases in Southeast Asian Rubber Plantations (2016)
Journal Article
Tangena, J., Thammavong, P., Wilson, A., Brey, P., & Lindsay, S. (2016). Risk and Control of Mosquito-Borne Diseases in Southeast Asian Rubber Plantations. Trends in Parasitology, 32(5), 402-415. https://doi.org/10.1016/j.pt.2016.01.009

Unprecedented economic growth in Southeast Asia (SEA) has encouraged the expansion of rubber plantations. This land-use transformation is changing the risk of mosquito-borne diseases. Mature plantations provide ideal habitats for the mosquito vectors... Read More about Risk and Control of Mosquito-Borne Diseases in Southeast Asian Rubber Plantations.

Vectorial capacity and vector control: reconsidering sensitivity to parameters for malaria elimination (2016)
Journal Article
Brady, O., Godfray, C., Tatem, A., Gething, P., Cohen, J., McKenzie, F., …Smith, D. (2016). Vectorial capacity and vector control: reconsidering sensitivity to parameters for malaria elimination. Transactions of The Royal Society of Tropical Medicine and Hygiene, 110(2), 107-117. https://doi.org/10.1093/trstmh/trv113

Background Major gains have been made in reducing malaria transmission in many parts of the world, principally by scaling-up coverage with long-lasting insecticidal nets and indoor residual spraying. Historically, choice of vector control interventio... Read More about Vectorial capacity and vector control: reconsidering sensitivity to parameters for malaria elimination.

The impact of climate on the abundance of Musca sorbens, the vector of trachoma (2016)
Journal Article
Ramesh, A., Bristow, J., Kovats, S., Lindsay, S., Haslam, D., Schmidt, E., & Gilbert, C. (2016). The impact of climate on the abundance of Musca sorbens, the vector of trachoma. Parasites and Vectors, 9(1), Article 48. https://doi.org/10.1186/s13071-016-1330-y

Background: To assess the extent to which climate may affect the abundance of Musca sorbens, a putative vector of trachoma. Data sources: Studies were identified by systematically searching online databases including CAB abstracts, Embase, Global Hea... Read More about The impact of climate on the abundance of Musca sorbens, the vector of trachoma.

Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda (2016)
Journal Article
Tusting, L., Rek, J., Arinaitwe, E., Staedke, S., Kamya, M., Bottomley, C., …Lindsay, S. (2016). Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda. American Journal of Tropical Medicine and Hygiene, 94(3), 650-658. https://doi.org/10.4269/ajtmh.15-0554

Socioeconomic position (SEP) is an important risk factor for malaria, but there is no consensus on how to measure SEP in malaria studies. We evaluated the relative strength of four indicators of SEP in predicting malaria risk in Nagongera, Uganda. A... Read More about Measuring Socioeconomic Inequalities in Relation to Malaria Risk: A Comparison of Metrics in Rural Uganda.

Armigeres subalbatus colonization of damaged pit latrines: a nuisance and potential health risk to residents of resettlement villages in Laos (2015)
Journal Article
Hiscox, A., Hirooka, R., Vongphayloth, K., Hill, N., Lindsay, S., Grandadam, M., & Brey, P. (2016). Armigeres subalbatus colonization of damaged pit latrines: a nuisance and potential health risk to residents of resettlement villages in Laos. Medical and Veterinary Entomology, 30(1), 95-100. https://doi.org/10.1111/mve.12142

During the resettlement of 6500 persons living around the Nam Theun 2 hydroelectric project in Laos, more than 1200 pour-flush latrines were constructed. To assess the role of these latrines as productive larval habitats for mosquitoes, entomological... Read More about Armigeres subalbatus colonization of damaged pit latrines: a nuisance and potential health risk to residents of resettlement villages in Laos.

Permethrin-Treated Clothing as Protection against the Dengue Vector, Aedes aegypti: Extent and Duration of Protection (2015)
Journal Article
DeRaedt Banks, S., Orsborne, J., Gezan, S., Kaur, H., Wilder-Smith, A., Lindsay, S., & Logan, J. (2015). Permethrin-Treated Clothing as Protection against the Dengue Vector, Aedes aegypti: Extent and Duration of Protection. PLoS Neglected Tropical Diseases, 9(10), Article e0004109. https://doi.org/10.1371/journal.pntd.0004109

Introduction Dengue transmission by the mosquito vector, Aedes aegypti, occurs indoors and outdoors during the day. Personal protection of individuals, particularly when outside, is challenging. Here we assess the efficacy and durability of different... Read More about Permethrin-Treated Clothing as Protection against the Dengue Vector, Aedes aegypti: Extent and Duration of Protection.

Integrating vector control across diseases (2015)
Journal Article
Golding, N., Wilson, A. L., Moyes, C. L., Cano, J., Pigott, D. M., Velayudhan, R., …Lindsay, S. W. (2015). Integrating vector control across diseases. BMC Medicine, 13(1), Article 249. https://doi.org/10.1186/s12916-015-0491-4

Background: Vector-borne diseases cause a significant proportion of the overall burden of disease across the globe, accounting for over 10 % of the burden of infectious diseases. Despite the availability of effective interventions for many of these d... Read More about Integrating vector control across diseases.

Associations between urbanicity and malaria at local scales in Uganda (2015)
Journal Article
Kigozi, S., Pindolia, D., Smith, D., Arinaitwe, E., Katureebe, A., Kilama, M., …Tatem, A. (2015). Associations between urbanicity and malaria at local scales in Uganda. Malaria Journal, 14(1), Article 374. https://doi.org/10.1186/s12936-015-0865-2

Background: Sub-Saharan Africa is expected to show the greatest rates of urbanization over the next 50 years. Urbanization has shown a substantial impact in reducing malaria transmission due to multiple factors, including unfavourable habitats for An... Read More about Associations between urbanicity and malaria at local scales in Uganda.

The Human-Baited Double Net Trap: An Alternative to Human Landing Catches for Collecting Outdoor Biting Mosquitoes in Lao PDR (2015)
Journal Article
Tangena, J., Thammavong, P., Hiscox, A., Lindsay, S., & Brey, P. (2015). The Human-Baited Double Net Trap: An Alternative to Human Landing Catches for Collecting Outdoor Biting Mosquitoes in Lao PDR. PLoS ONE, 10(9), Article e0138735. https://doi.org/10.1371/journal.pone.0138735

Estimating the exposure of individuals to mosquito-borne diseases is a key measure used to evaluate the success of vector control operations. The gold standard is to use human landing catches where mosquitoes are collected off the exposed limbs of hu... Read More about The Human-Baited Double Net Trap: An Alternative to Human Landing Catches for Collecting Outdoor Biting Mosquitoes in Lao PDR.

Entomological monitoring and evaluation: diverse transmission settings of ICEMR projects will require local and regional malaria elimination strategies (2015)
Journal Article
Conn, J., Norris, D., Donnelly, M., Beebe, N., Burkot, T., Coulibaly, M., …Yan, G. (2015). Entomological monitoring and evaluation: diverse transmission settings of ICEMR projects will require local and regional malaria elimination strategies. American Journal of Tropical Medicine and Hygiene, 93(3 Supplement), 28-41. https://doi.org/10.4269/ajtmh.15-0009

The unprecedented global efforts for malaria elimination in the past decade have resulted in altered vectorial systems, vector behaviors, and bionomics. These changes combined with increasingly evident heterogeneities in malaria transmission require... Read More about Entomological monitoring and evaluation: diverse transmission settings of ICEMR projects will require local and regional malaria elimination strategies.

Analysing the oviposition behaviour of malaria mosquitoes: design considerations for improving two-choice egg count experiments (2015)
Journal Article
Okal, M., Lindh, J., Torr, S., Masinde, E., Orindi, B., Lindsay, S., & Fillinger, U. (2015). Analysing the oviposition behaviour of malaria mosquitoes: design considerations for improving two-choice egg count experiments. Malaria Journal, 14, Article 250. https://doi.org/10.1186/s12936-015-0768-2

Background Choice egg-count bioassays are a popular tool for analysing oviposition substrate preferences of gravid mosquitoes. This study aimed at improving the design of two-choice experiments for measuring oviposition substrates preferences of the... Read More about Analysing the oviposition behaviour of malaria mosquitoes: design considerations for improving two-choice egg count experiments.

The evidence for improving housing to reduce malaria: a systematic review and meta-analysis (2015)
Journal Article
Tusting, L., Ippolito, M., Willey, B., Kleinschmidt, I., Dorsey, G., Gosling, R., & Lindsay, S. (2015). The evidence for improving housing to reduce malaria: a systematic review and meta-analysis. Malaria Journal, 14, Article 209. https://doi.org/10.1186/s12936-015-0724-1

Background The global malaria burden has fallen since 2000, sometimes before large-scale vector control programmes were initiated. While long-lasting insecticide-treated nets and indoor residual spraying are highly effective interventions, this study... Read More about The evidence for improving housing to reduce malaria: a systematic review and meta-analysis.

Evidence-based vector control? Improving the quality of vector control trials (2015)
Journal Article
Wilson, A., Boelaert, M., Kleinschmidt, I., Pinder, M., Scott, T., Tusting, L., & Lindsay, S. (2015). Evidence-based vector control? Improving the quality of vector control trials. Trends in Parasitology, 31(8), 380-390. https://doi.org/10.1016/j.pt.2015.04.015

Vector-borne diseases (VBDs) such as malaria, dengue, and leishmaniasis cause a high level of morbidity and mortality. Although vector control tools can play a major role in controlling and eliminating these diseases, in many cases the evidence base... Read More about Evidence-based vector control? Improving the quality of vector control trials.

Malaria Transmission, Infection, and Disease at Three Sites with Varied Transmission Intensity in Uganda: Implications for Malaria Control (2015)
Journal Article
Kamya, M. R., Kilama, M., Lindsay, S. W., Greenhouse, B., Arinaitwe, E., Staedke, S. G., …Dorsey, G. (in press). Malaria Transmission, Infection, and Disease at Three Sites with Varied Transmission Intensity in Uganda: Implications for Malaria Control. American Journal of Tropical Medicine and Hygiene, 92(5), https://doi.org/10.4269/ajtmh.14-0312

To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: study protocol for a randomised controlled trial (2015)
Journal Article
Sagnon, N., Pinder, M., Tchicaya, E., Tiono, A., Faragher, B., Ranson, H., & Lindsay, S. (2015). To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: study protocol for a randomised controlled trial. Trials, 16(1), https://doi.org/10.1186/s13063-015-0700-7

Background: The effectiveness of pyrethroid-treated bednets for malaria control in sub-Saharan Africa is under threat because of high levels of resistance to pyrethroid insecticides in the vectors. Here we assess the durability of polyethylene nets w... Read More about To assess whether addition of pyriproxyfen to long-lasting insecticidal mosquito nets increases their durability compared to standard long-lasting insecticidal mosquito nets: study protocol for a randomised controlled trial.

Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex (2015)
Journal Article
Lindh, J., Okal, M., Herrera-Varela, M., Borg-Karlson, A., Torto, B., Lindsay, S., & Fillinger, U. (2015). Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex. Malaria Journal, 14(3), Article 119. https://doi.org/10.1186/s12936-015-0636-0

Background New strategies are needed to manage malaria vector populations that resist insecticides and bite outdoors. This study describes a breakthrough in developing ‘attract and kill’ strategies targeting gravid females by identifying and evaluati... Read More about Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex.

The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial (2015)
Journal Article
Tiono, A., Pinder, M., N'Fale, S., Faragher, B., Smith, T., Silkey, M., …Lindsay, S. (2015). The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial. Trials, 16, Article 113. https://doi.org/10.1186/s13063-015-0606-4

Background: Recent reductions in malaria in sub-Saharan Africa have been associated with increased coverage with long-lasting insecticidal nets (LLINs). Pyrethroids are currently the only insecticide class used for treating nets, and the rapid increa... Read More about The AvecNet Trial to assess whether addition of pyriproxyfen, an insect juvenile hormone mimic, to long-lasting insecticidal mosquito nets provides additional protection against clinical malaria over current best practice in an area with pyrethroid-resistant vectors in rural Burkina Faso: study protocol for a randomised controlled trial.

Adult vector control, mosquito ecology and malaria transmission (2015)
Journal Article
Brady, O., Godfray, H., Tatem, A., Gething, P., Cohen, J., McKenzie, F., …Smith, D. (2015). Adult vector control, mosquito ecology and malaria transmission. International Health, 7(2), 121-129. https://doi.org/10.1093/inthealth/ihv010

Background: Standard advice regarding vector control is to prefer interventions that reduce the lifespan of adult mosquitoes. The basis for this advice is a decades-old sensitivity analysis of ‘vectorial capacity’, a concept relevant for most malaria... Read More about Adult vector control, mosquito ecology and malaria transmission.

Mind the gap: house structure and the risk of malaria in Uganda (2015)
Journal Article
Wanzirah, H., Tusting, L., Arinaitwe, E., Katureebe, A., Maxwell, K., Rek, J., …Lindsay, S. (2015). Mind the gap: house structure and the risk of malaria in Uganda. PLoS ONE, 10(1), https://doi.org/10.1371/journal.pone.0117396

Background: Good house construction may reduce the risk of malaria by limiting the entry of mosquito vectors. We assessed how house design may affect mosquito house entry and malaria risk in Uganda. Methods: 100 households were enrolled in each of th... Read More about Mind the gap: house structure and the risk of malaria in Uganda.

How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector? (2014)
Journal Article
Stone, C., Lindsay, S., & Chitnis, N. (2014). How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?. PLoS Neglected Tropical Diseases, 8(12), Article e3393. https://doi.org/10.1371/journal.pntd.0003393

Background: The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF) control where both diseases are transmitted by the same vector. To date most examples... Read More about How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?.

Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial (2014)
Journal Article
Pinder, M., Jawara, M., Jarju, L., Salami, K., Jeffries, D., Adiamoh, M., …Lindsay, S. (2015). Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial. The Lancet, 385(9976), 1436-1446. https://doi.org/10.1016/s0140-6736%2814%2961007-2

Background: Although many malaria control programmes in sub-Saharan Africa use indoor residual spraying with long-lasting insecticidal nets (LLINs), the two studies assessing the benefit of the combination of these two interventions gave conflicting... Read More about Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets : a cluster-randomised controlled trial.

Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis (2014)
Journal Article
Wilson, A., Chen-Hussey, V., Logan, J., & Lindsay, S. (2014). Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis. Malaria Journal, 13(1), Article 446. https://doi.org/10.1186/1475-2875-13-446

Background: Recommended vector control tools against malaria, such as long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), mainly target mosquitoes that rest and feed on human hosts indoors. However, in some malaria-endemic area... Read More about Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis.

The global distribution and transmission limits of lymphatic filariasis: past and present (2014)
Journal Article
Cano, J., Rebollo, M., Golding, N., Pullan, R., Crellen, T., Soler, A., …Brooker, S. (2014). The global distribution and transmission limits of lymphatic filariasis: past and present. Parasites and Vectors, 7(1), https://doi.org/10.1186/s13071-014-0466-x

Background: Lymphatic filariasis (LF) is one of the neglected tropical diseases targeted for global elimination by 2020 and to guide elimination efforts countries have, in recent years, conducted extensive mapping surveys. Documenting the past and pr... Read More about The global distribution and transmission limits of lymphatic filariasis: past and present.

Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis (2014)
Journal Article
Wilson, A., Dhiman, R., Kitron, U., Scott, T., van den Berg, H., & Lindsay, S. (2014). Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis. PLoS Neglected Tropical Diseases, 8(10), Article e3228. https://doi.org/10.1371/journal.pntd.0003228

Introduction: Insecticide-treated nets (ITNs) are one of the main interventions used for malaria control. However, these nets may also be effective against other vector borne diseases (VBDs). We conducted a systematic review and meta-analysis to esti... Read More about Benefit of Insecticide-Treated Nets, Curtains and Screening on Vector Borne Diseases, Excluding Malaria: A Systematic Review and Meta-analysis.

Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect (2014)
Journal Article
Mbare, O., Lindsay, S., & Fillinger, U. (2014). Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect. Parasites and Vectors, 7, Article 438. https://doi.org/10.1186/1756-3305-7-438

Background: Persistent monomolecular surface films could benefit larval source management for malaria control by reducing programme costs and managing insecticide resistance. This study evaluated the efficacy of the silicone-based surface film, Aquat... Read More about Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles Gambaie sensu stricto and Anopheles arabiensis : dose-responses, persistence and sub-lethal effect.

Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus (2014)
Journal Article
Mbare, O., Lindsay, S., & Fillinger, U. (2014). Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus. Parasites and Vectors, 7(6), Article 280. https://doi.org/10.1186/1756-3305-7-280

Background: The use of gravid mosquitoes as vehicles to auto-disseminate larvicides was recently demonstrated for the transfer of pyriproxyfen (PPF) by container-breeding Aedes mosquitoes and presents an appealing idea to explore for other disease ve... Read More about Pyriproxyfen for mosquito control:female sterilization or horizontal transfer to ovipsoition substrates by Anopheles gambaie sensu stricto and Culex quinquefasciatus.

Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s (2014)
Journal Article
Dugassa, S., Lindh, J., Torr, S., Lindsay, S., & Fillinger, U. (2014). Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s. Parasites and Vectors, 7(6), Article 272. https://doi.org/10.1186/1756-3305-7-272

Background: Electric nets (e-nets) are used to analyse the flight behaviour of insects and have been used extensively to study the host-oriented flight of tsetse flies. Recently we adapted this tool to analyse the oviposition behaviour of gravid mala... Read More about Evaluation of the influence of electric nets on the behaviour of oviposition site seeking Anopheles gambaie s.s.

A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens (2014)
Journal Article
Guerra, C., Reiner Jr, R., Perkins, T., Lindsay, S., Midega, J., Brady, O., …Smith, D. (2014). A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens. Parasites and Vectors, 7(6), Article 276. https://doi.org/10.1186/1756-3305-7-276

Background: Pathogen transmission by mosquitos is known to be highly sensitive to mosquito bionomic parameters. Mosquito mark-release-recapture (MMRR) experiments are a standard method for estimating such parameters including dispersal, population si... Read More about A global assembly of adult female mosquito mark-release-recapture data to inform the control of mosquito-borne pathogens.

Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system (2014)
Journal Article
Herrera-Varela, M., Lindh, J., Lindsay, S., & Fillinger, U. (2014). Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system. Malaria Journal, 13, Article 133. https://doi.org/10.1186/1475-2875-13-133

Background: The non-random distribution of anopheline larvae in natural habitats suggests that gravid females discriminate between habitats of different quality. Whilst physical and chemical cues used by Culex and Aedes vector mosquitoes for selectin... Read More about Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system.

Framework for rapid assessment and adoption of new vector control tools (2014)
Journal Article
Vontas, J., Moore, S., Kleinschmidt, I., Ranson, H., Lindsay, S., Lengeler, C., …Hemingway, J. (2014). Framework for rapid assessment and adoption of new vector control tools. Trends in Parasitology, 30(4), 191-204. https://doi.org/10.1016/j.pt.2014.02.005

Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) u... Read More about Framework for rapid assessment and adoption of new vector control tools.

Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda (2014)
Journal Article
Kilama, M., Smith, D., Hutchinson, R., Kigozi, R., Yeka, A., Lavoy, G., …Lindsay, S. (2014). Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda. Malaria Journal, 13, Article 111. https://doi.org/10.1186/1475-2875-13-111

Background: The Plasmodium falciparum entomological inoculation rate (PfEIR) is a measure of exposure to infectious mosquitoes. It is usually interpreted as the number of P. falciparum infective bites received by an individual during a season or annu... Read More about Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda.

Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto (2013)
Journal Article
Okal, M., Francis, B., Herrera-Varela, M., Fillinger, U., & Lindsay, S. (2013). Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto. Malaria Journal, 12(10), Article 365. https://doi.org/10.1186/1475-2875-12-365

Background: To date no semiochemicals affecting the pre-oviposition behaviour of the malaria vector Anopheles gambiae sensu lato have been described. Water vapour must be the major chemical signal emanating from a potential larval habitat, and althou... Read More about Water vapour is a pre-oviposition attractant for the malaria vector Anopheles gambaie sensu stricto.

Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis (2013)
Journal Article
Tusting, L., Willey, B., Lucas, H., Thompson, J., Kafy, H., Smith, R., & Lindsay, S. (2013). Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis. The Lancet, 382(9896), 963-972. https://doi.org/10.1016/s0140-6736%2813%2960851-x

Background Future progress in tackling malaria mortality will probably be hampered by the development of resistance to drugs and insecticides and by the contraction of aid budgets. Historically, control was often achieved without malaria-specific int... Read More about Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis.

Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia (2013)
Journal Article
Tangena, J., Majida, A., D'Alessandro, U., Jarju, L., Jawara, M., Jeffries, D., …Pinder, M. (2013). Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia. PLoS ONE, 8(9), Article e74351. https://doi.org/10.1371/journal.pone.0074351

Background: Malaria vector control is threatened by resistance to pyrethroids, the only class of insecticides used for treating bed nets. The second major vector control method is indoor residual spraying with pyrethroids or the organochloride DDT. H... Read More about Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia.

Mosquito larval source management for controlling malaria (2013)
Journal Article
Tusting, L., Thwing, J., Sinclair, D., Fillinger, U., Gimnig, J., Bonner, K., …Lindsay, S. (2013). Mosquito larval source management for controlling malaria. Cochrane Database of Systematic Reviews, 2013(8), Article CD008923. https://doi.org/10.1002/14651858.cd008923.pub2

Background Malaria is an important cause of illness and death in people living in many parts of the world, especially sub-Saharan Africa. Long-lasting insecticide treated bed nets (LLINs) and indoor residual spraying (IRS) reduce malaria transmission... Read More about Mosquito larval source management for controlling malaria.

Can Topical Insect Repellents Reduce Malaria? A Cluster-Randomised Controlled Trial of the Insect Repellent N,N-diethyl-m-toluamide (DEET) in Lao PDR (2013)
Journal Article
Chen-Hussey, V., Carneiro, I., Keomanila, H., Gray, R., Bannavong, S., Phanalasy, S., & Lindsay, S. (2013). Can Topical Insect Repellents Reduce Malaria? A Cluster-Randomised Controlled Trial of the Insect Repellent N,N-diethyl-m-toluamide (DEET) in Lao PDR. PLoS ONE, 8(8), Article e70664. https://doi.org/10.1371/journal.pone.0070664

Background: Mosquito vectors of malaria in Southeast Asia readily feed outdoors making malaria control through indoor insecticides such as long-lasting insecticidal nets (LLINs) and indoor residual spraying more difficult. Topical insect repellents m... Read More about Can Topical Insect Repellents Reduce Malaria? A Cluster-Randomised Controlled Trial of the Insect Repellent N,N-diethyl-m-toluamide (DEET) in Lao PDR.

Mosquito Population Regulation and Larval Source Management in Heterogeneous Environments (2013)
Journal Article
Smith, D., Perkins, T., Tusting, L., Scott, T., & Lindsay, S. (2013). Mosquito Population Regulation and Larval Source Management in Heterogeneous Environments. PLoS ONE, 8(8), Article e71247. https://doi.org/10.1371/journal.pone.0071247

An important question for mosquito population dynamics, mosquito-borne pathogen transmission and vector control is how mosquito populations are regulated. Here we develop simple models with heterogeneity in egg laying patterns and in the responses of... Read More about Mosquito Population Regulation and Larval Source Management in Heterogeneous Environments.

Development of a Gravid Trap for Collecting Live Malaria Vectors Anopheles gambiae s.l (2013)
Journal Article
Dugassa, S., Lindh, J., Oyieke, F., Mukabana, R., Lindsay, S., & Fillinger, U. (2013). Development of a Gravid Trap for Collecting Live Malaria Vectors Anopheles gambiae s.l. PLoS ONE, 8(7), Article e68948. https://doi.org/10.1371/journal.pone.0068948

Background: Effective malaria vector control targeting indoor host-seeking mosquitoes has resulted in fewer vectors entering houses in many areas of sub-Saharan Africa, with the proportion of vectors outdoors becoming more important in the transmissi... Read More about Development of a Gravid Trap for Collecting Live Malaria Vectors Anopheles gambiae s.l.

Risk factors for the presence of Stegomyia aegypti and Stegomyia albopictus in domestic water-holding containers in areas impacted by Nam Theun 2 Hydroelectric Project, Laos (2013)
Journal Article
Hiscox, A., Kaye, A., Vongphayloth, K., Banks, I., Piffer, M., Khammanithong, P., …Brey, P. (2013). Risk factors for the presence of Stegomyia aegypti and Stegomyia albopictus in domestic water-holding containers in areas impacted by Nam Theun 2 Hydroelectric Project, Laos. American Journal of Tropical Medicine and Hygiene, 88(6), 1070-1078. https://doi.org/10.4269/ajtmh.12-0623

We assessed risk factors for vectors of dengue and chikungunya viruses near a new hydroelectric project, Nam Theun 2, in Laos. Immature stages of Aedes aegypti were found only in sites within 40 km of the urban provincial capital, but Aedes albopictu... Read More about Risk factors for the presence of Stegomyia aegypti and Stegomyia albopictus in domestic water-holding containers in areas impacted by Nam Theun 2 Hydroelectric Project, Laos.

Risk factors for mosquito house entry in the Lao PDR (2013)
Journal Article
Hiscox, A., Khammanithing, P., Laul, S., Sannanikhom, P., Luthi, R., Hill, N., …Lindsay, S. (2013). Risk factors for mosquito house entry in the Lao PDR. PLoS ONE, 8(5), https://doi.org/10.1371/journal.pone.0062769

Background: Construction of the Nam Theun 2 hydroelectric project and flooding of a 450 km2 area of mountain plateau in south-central Lao PDR resulted in the resettlement of 6,300 people to newly built homes. We examined whether new houses would have... Read More about Risk factors for mosquito house entry in the Lao PDR.

A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970-2010 (2013)
Journal Article
Reiner, R., Perkins, T., Barker, C., Niu, T., Fernando Chaves, L., Ellis, A., …Smith, D. (2013). A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970-2010. Journal of the Royal Society. Interface, 10(81), Article 20120921. https://doi.org/10.1098/rsif.2012.0921

Mathematical models of mosquito-borne pathogen transmission originated in the early twentieth century to provide insights into how to most effectively combat malaria. The foundations of the Ross–Macdonald theory were established by 1970. Since then,... Read More about A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970-2010.

The importance of mosquito behavioural adaptations to malaria control in Africa (2013)
Journal Article
Gatton, M., Chitnis, N., Churcher, T., Donnelly, M., Ghani, A., Godfray, C., …Lindsay, S. (2013). The importance of mosquito behavioural adaptations to malaria control in Africa. Evolution: International Journal of Organic Evolution, 67(4), 1218-1230. https://doi.org/10.1111/evo.12063

Over the past decade the use of long-lasting insecticidal nets (LLINs), in combination with improved drug therapies, indoor residual spraying (IRS), and better health infrastructure, has helped reduce malaria in many African countries for the first t... Read More about The importance of mosquito behavioural adaptations to malaria control in Africa.

Dose-response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato (2013)
Journal Article
Mbare, O., Lindsay, S., & Fillinger, U. (2013). Dose-response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato. Malaria Journal, 12, Article 94. https://doi.org/10.1186/1475-2875-12-94

Background: Recently research has shown that larviciding can be an effective tool for integrated malaria vector control. Nevertheless, the uptake of this intervention has been hampered by the need to re-apply larvicides frequently. There is a need to... Read More about Dose-response tests and semi-field evaluation of lethal and sub-lethal effects of slow release pyriproxyfen granules (Sumilarv®0.5G) for the control of the malaria vectors Anopheles gambiae sensu lato.

Preliminary studies developing methods for the control of Chrysomya putoria, the African latrine fly, in pit latrines in The Gambia (2013)
Journal Article
Lindsay, T., Jawara, M., D'Alessandro, U., Pinder, M., & Lindsay, S. (2013). Preliminary studies developing methods for the control of Chrysomya putoria, the African latrine fly, in pit latrines in The Gambia. Tropical Medicine and International Health, 18(2), 159-165. https://doi.org/10.1111/tmi.12033

Objective To explore ways of controlling Chrysomya putoria, the African latrine fly, in pit latrines. As pit latrines are a major source of these flies, eliminating these important breeding sites is likely to reduce village fly populations, and may r... Read More about Preliminary studies developing methods for the control of Chrysomya putoria, the African latrine fly, in pit latrines in The Gambia.

Malaria and lymphatic filariasis: the case for integrated vector management (2013)
Journal Article
van den Berg, H., Kelly-Hope, L., & Lindsay, S. (2013). Malaria and lymphatic filariasis: the case for integrated vector management. The Lancet Infectious Diseases, 13(1), 89-94. https://doi.org/10.1016/s1473-3099%2812%2970148-2

The global programmes to eliminate both malaria and lymphatic filariasis are facing operational and technical challenges. Available data show that the use of treated or untreated bednets and indoor residual spraying for malaria control concomitantly... Read More about Malaria and lymphatic filariasis: the case for integrated vector management.

Development of odour-baited flytraps for sampling the African latrine fly, Chrysomya putoria, a putative vector of enteric diseases (2012)
Journal Article
Lindsay, T., Jawara, M., D'Alessandro, U., Pinder, M., & Lindsay, S. (2012). Development of odour-baited flytraps for sampling the African latrine fly, Chrysomya putoria, a putative vector of enteric diseases. PLoS ONE, 7(11), Article e50505. https://doi.org/10.1371/journal.pone.0050505

African pit latrines produce prodigious numbers of the latrine fly, Chrysomya putoria, a putative vector of diarrhoeal pathogens. We set out to develop a simple, low-cost odour-baited trap for collecting C. putoria in the field. A series of field exp... Read More about Development of odour-baited flytraps for sampling the African latrine fly, Chrysomya putoria, a putative vector of enteric diseases.

The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand (2012)
Journal Article
Wilder-Smith, A., Byass, P., Olanratmanee, P., Maskhao, P., Sringernyuang, L., Logan, J., …Kittayapong, P. (2012). The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand. Trials, 13(11), Article 212. https://doi.org/10.1186/1745-6215-13-212

Background: There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where childr... Read More about The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand.

Electric nets and sticky materials for analysing oviposition behaviour of gravid malaria vectors (2012)
Journal Article
Dugassa, S., Lindh, J., Torr, S., Oyieke, F., Lindsay, S., & Fillinger, U. (2012). Electric nets and sticky materials for analysing oviposition behaviour of gravid malaria vectors. Malaria Journal, 11(1), Article 374. https://doi.org/10.1186/1475-2875-11-374

Background Little is known about how malaria mosquitoes locate oviposition sites in nature. Such knowledge is important to help devise monitoring and control measures that could be used to target gravid females. This study set out to develop a suite... Read More about Electric nets and sticky materials for analysing oviposition behaviour of gravid malaria vectors.

Chrysomya putoria, a putative vector of diarrheal diseases (2012)
Journal Article
Lindsay, S., Lindsay, T., Duprez, J., Hall, M., Kwambana, B., Jawara, M., …Antonio, M. (2012). Chrysomya putoria, a putative vector of diarrheal diseases. PLoS Neglected Tropical Diseases, 6(11), Article e1895. https://doi.org/10.1371/journal.pntd.0001895

African pit latrines produce prodigious numbers of the latrine fly, Chrysomya putoria, a putative vector of diarrhoeal pathogens. We set out to develop a simple, low-cost odour-baited trap for collecting C. putoria in the field. A series of field exp... Read More about Chrysomya putoria, a putative vector of diarrheal diseases.

Promoting health and advancing development through improved housing in low-income setings (2012)
Journal Article
Haines, A., Bruce, N., Cairncross, S., Davies, M., Greenland, K., Hiscox, A., …Wilkinson, P. (2012). Promoting health and advancing development through improved housing in low-income setings. Journal of Urban Health, 90(5), 810-831. https://doi.org/10.1007/s11524-012-9773-8

There is major untapped potential to improve health in low-income communities through improved housing design, fittings, materials and construction. Adverse effects on health from inadequate housing can occur through a range of mechanisms, both direc... Read More about Promoting health and advancing development through improved housing in low-income setings.

Modeling the role of environmental variables on the population dynamics of the malaria vector Anopheles gambiae sensu stricto (2012)
Journal Article
Parham, P., Pople, D., Christiansen-Junct, C., Lindsay, S., Winsley, W., & Michael, E. (2012). Modeling the role of environmental variables on the population dynamics of the malaria vector Anopheles gambiae sensu stricto. Malaria Journal, 11, Article 271. https://doi.org/10.1186/1475-2875-11-271

Background The impact of weather and climate on malaria transmission has attracted considerable attention in recent years, yet uncertainties around future disease trends under climate change remain. Mathematical models provide powerful tools for addr... Read More about Modeling the role of environmental variables on the population dynamics of the malaria vector Anopheles gambiae sensu stricto.

Spatial repellents: from discovery and development to evidence based validation (2012)
Journal Article
Achee, N., Bangs, M., Farlow, R., Killeen, G., Lindsay, S., Logan, J., …Grieco, J. (2012). Spatial repellents: from discovery and development to evidence based validation. Malaria Journal, 11, Article 164. https://doi.org/10.1186/1475-2875-11-164

International public health workers are challenged by a burden of arthropod-borne disease that remains elevated despite best efforts in control programmes. With this challenge comes the opportunity to develop novel vector control paradigms to guide p... Read More about Spatial repellents: from discovery and development to evidence based validation.

Selection of mosquito life-histories: a hidden weapon against malaria? (2012)
Journal Article
Ferguson, H., Maire, N., Takken, W., Lyimo, I., Briet, O., Lindsay, S., & Smith, T. (2012). Selection of mosquito life-histories: a hidden weapon against malaria?. Malaria Journal, 11, Article 106. https://doi.org/10.1186/1475-2875-11-106

Background: There has recently been a substantial decline in malaria incidence in much of Africa. While the decline can clearly be linked to increasing coverage of mosquito vector control interventions and effective drug treatment in most settings, t... Read More about Selection of mosquito life-histories: a hidden weapon against malaria?.

DengueTools: Innovative tools and strategies for surveillance and control of dengue (2012)
Journal Article
Wilder-Smith, A., Renhorn, K., Tissera, H., Bakar, S., Alphey, L., Kittayapong, P., …Gubler, D. (2012). DengueTools: Innovative tools and strategies for surveillance and control of dengue. Global Health Action, 5, Article 17273. https://doi.org/10.3402/gha.v5i0.17273

Dengue fever is a mosquito-borne viral disease estimated to cause about 230 million infectionsworldwide every year, of which 25,000 are fatal. Global incidence has risen rapidly in recent decades with some 3.6 billion people, over half of the world’s... Read More about DengueTools: Innovative tools and strategies for surveillance and control of dengue.

Larval source management for malaria control in Africa: myths and reality (2011)
Journal Article
Fillinger, U., & Lindsay, S. (2011). Larval source management for malaria control in Africa: myths and reality. Malaria Journal, 10, Article 353. https://doi.org/10.1186/1475-2875-10-353

As malaria declines in many African countries there is a growing realization that new interventions need to be added to the front-line vector control tools of long-lasting impregnated nets (LLINs) and indoor residual spraying (IRS) that target adult... Read More about Larval source management for malaria control in Africa: myths and reality.

To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised study (2011)
Journal Article
Pinder, M., Jawara, M., Jarju, L., Ballah, K., Jeffries, D., Lluberas, M., …Lindsay, S. (2011). To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised study. Trials, 12, https://doi.org/10.1186/1745-6215-12-147

Background: Recently, there has been mounting interest in scaling-up vector control against malaria in Africa. It needs to be determined if indoor residual spraying (IRS with DDT) will provide significant marginal protection against malaria over curr... Read More about To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised study.

A research agenda for malaria eradication: vector control (2011)
Journal Article
Control, T. M. C. G. O. V. (2011). A research agenda for malaria eradication: vector control. PLoS Medicine, 8, https://doi.org/10.1371/journal.pmed.1000401

Different challenges are presented by the variety of malaria transmission environments present in the world today. In each setting, improved control for reduction of morbidity is a necessary first step towards the long-range goal of malaria eradicati... Read More about A research agenda for malaria eradication: vector control.

Social acceptability and durability of two different house screening interventions against exposure to malaria vectors, Plasmodium falciparum infection and anaemia in children in The Gambia, West Africa. (2010)
Journal Article
Kirby, M., Ba, P., Jones, C., Kelly, A., Jasseh, M., & Lindsay, S. (2010). Social acceptability and durability of two different house screening interventions against exposure to malaria vectors, Plasmodium falciparum infection and anaemia in children in The Gambia, West Africa. American Journal of Tropical Medicine and Hygiene, 83, 965-972. https://doi.org/10.4269/ajtmh.2010.10-0311

Is mosquito larval source management appropriate for reducing malaria in areas of extensive flooding in The Gambia? A cross-over intervention trial (2010)
Journal Article
Majambere, S., Pinder, M., Fillinger, U., Ameh, D., Conway, D., Green, C., …Lindsay, S. (2010). Is mosquito larval source management appropriate for reducing malaria in areas of extensive flooding in The Gambia? A cross-over intervention trial. American Journal of Tropical Medicine and Hygiene, 82(2), 176-184. https://doi.org/10.4269/ajtmh.2010.09-0373

'Like sugar and honey': the embedded ethics of a larval control project in The Gambia (2010)
Journal Article
Kelly, A., Ameh, D., Majambere, S., Lindsay, S., & Pinder, M. (2010). 'Like sugar and honey': the embedded ethics of a larval control project in The Gambia. Social Science & Medicine, 70(12), 1912-1919. https://doi.org/10.1016/j.socscimed.2010.02.012

This paper describes a malaria research project in The Gambia to provoke thinking on the social value of transnational research. The Larval Control Project (LCP) investigated the efficacy of a microbial insecticide to reduce vector density and, ultim... Read More about 'Like sugar and honey': the embedded ethics of a larval control project in The Gambia.

Assessing the future threat from vivax malaria in the United Kingdom using two markedly different modelling approaches (2010)
Journal Article
Lindsay, S., Hole, D., Hutchinson, R., Richards, S., & Willis, S. (2010). Assessing the future threat from vivax malaria in the United Kingdom using two markedly different modelling approaches. Malaria Journal, 9, https://doi.org/10.1186/1475-2875-9-70

Background: The world is facing an increased threat from new and emerging diseases, and there is concern that climate change will expand areas suitable for transmission of vector borne diseases. The likelihood of vivax malaria returning to the UK was... Read More about Assessing the future threat from vivax malaria in the United Kingdom using two markedly different modelling approaches.

Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial (2009)
Journal Article
Kirby, M., Ameh, D., Bottomley, C., Green, C., Jawara, M., Milligan, P., …Lindsay, S. (2009). Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial. The Lancet, 374(9694), 998-1009. https://doi.org/10.1016/s0140-6736%2809%2960871-0

Background: House screening should protect people against malaria. We assessed whether two types of house screening—full screening of windows, doors, and closing eaves, or installation of screened ceilings—could reduce house entry of malaria vectors... Read More about Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial.

Integrated malaria vector control with microbial larvicides and insecticide-treated nets in the western Kenya: a controlled trial (2009)
Journal Article
Fillinger, U., Ndenga, B., Githeko, A., & Lindsay, S. (2009). Integrated malaria vector control with microbial larvicides and insecticide-treated nets in the western Kenya: a controlled trial. Bulletin of the World Health Organization, 87, 655-665. https://doi.org/10.2471/blt.08.055632

Objective To assess the contributions of both microbial larvicides and insecticide-treated nets (ITNs) in terms of reducing malaria incidence in an integrated vector management programme in an area moderately endemic for malaria in the western Kenyan... Read More about Integrated malaria vector control with microbial larvicides and insecticide-treated nets in the western Kenya: a controlled trial.

Role of fish as predators of mosquito larvae on the floodplain of the Gambia River. (2009)
Journal Article
Louca, V., Lucas, M., Green, C., Majambere, S., Fillinger, U., & Lindsay, S. (2009). Role of fish as predators of mosquito larvae on the floodplain of the Gambia River. Journal of Medical Entomology, 46(3), 546-556. https://doi.org/10.1603/033.046.0320

We examined the potential of using native fish species in regulating mosquitoes in the floodplain of the Gambia River, the major source of mosquitoes in rural parts of The Gambia. Fishes and mosquito larvae were sampled along two 2.3-km-long transect... Read More about Role of fish as predators of mosquito larvae on the floodplain of the Gambia River..

Importance of eaves to house entry by Anopheline, but not Culicine, mosquitoes. (2009)
Journal Article
Njie, M., Dilger, E., Lindsay, S., & Kirby, M. (2009). Importance of eaves to house entry by Anopheline, but not Culicine, mosquitoes. Journal of Medical Entomology, 46(3), 505-510. https://doi.org/10.1603/033.046.0314

Screening homes is an effective way of reducing house entry by mosquitoes. Here, we assess how important blocking the eaves is for reducing house entry by anopheline and culicine mosquitoes for houses that have screened doors and no windows. Twelve h... Read More about Importance of eaves to house entry by Anopheline, but not Culicine, mosquitoes..

Microbial Larvicide Application by a Large-Scale, Community-Based Program Reduces Malaria Infection Prevalence in Urban Dar Es Salaam, Tanzania (2009)
Journal Article
Geissbühler, Y., Kannady, K., Chaki, P. P., Emidi, B., Govella, N. J., Mayagaya, V., …Killeen, G. F. (2009). Microbial Larvicide Application by a Large-Scale, Community-Based Program Reduces Malaria Infection Prevalence in Urban Dar Es Salaam, Tanzania. PLoS ONE, 4(3), Article e5107. https://doi.org/10.1371/journal.pone.0005107

Background Malaria control in Africa is most tractable in urban settlements yet most research has focused on rural settings. Elimination of malaria transmission from urban areas may require larval control strategies that complement adult mosquito con... Read More about Microbial Larvicide Application by a Large-Scale, Community-Based Program Reduces Malaria Infection Prevalence in Urban Dar Es Salaam, Tanzania.

Fish community characteristics of the lower Gambia River floodplains: a study in the last major undisturbed West African river (2009)
Journal Article
Louca, V., Lindsay, S., Majambere, S., & Lucas, M. (2009). Fish community characteristics of the lower Gambia River floodplains: a study in the last major undisturbed West African river. Freshwater Biology, 54(2), 254-271. https://doi.org/10.1111/j.1365-2427.2008.02105.x

1. The Gambia River is the last major West African river that has not been impounded. However, a hydroelectric dam is being constructed and substantial changes to the hydrology and ecology of the system are expected. 2. Little information is availabl... Read More about Fish community characteristics of the lower Gambia River floodplains: a study in the last major undisturbed West African river.

Spatial distribution of mosquito larvae and the potential for targeted larval control in The Gambia. (2008)
Journal Article
Majambere, S., Fillinger, U., Sayer, D., Green, C., & Lindsay, S. (2008). Spatial distribution of mosquito larvae and the potential for targeted larval control in The Gambia. American Journal of Tropical Medicine and Hygiene, 79(1), 19-27

We examined the distribution of aquatic stages of malaria vectors in a 400-km2 area in rural Gambia to assess the practicality of targeting larval control. During the rainy season, the peak period of malaria transmission, breeding sites were 70% more... Read More about Spatial distribution of mosquito larvae and the potential for targeted larval control in The Gambia..

Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia (2008)
Journal Article
Kirby, M., Milligan, P., Conway, D., & Lindsay, S. (2008). Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia. Trials, 9, Article 33. https://doi.org/10.1186/1745-6215-9-33

Background: Mosquito-proofing homes was one of the principal methods of environmental management in the early 1900s. House screening provides protection against malaria by reducing exposure to malaria parasites and has the added benefit of protecting... Read More about Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia.

Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia (2008)
Journal Article
Kirby, M., Green, C., Milligan, P., Charalambos, S., Jasseh, M., Conway, D., & Lindsay, S. (2008). Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia. Malaria Journal, 7, Article 2. https://doi.org/10.1186/1475-2875-7-2

Background: In the pre-intervention year of a randomized controlled trial investigating the protective effects of house screening against malaria-transmitting vectors, a multi-factorial risk factor analysis study was used to identify factors that inf... Read More about Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia.

A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Program in Dar es Salaam, Tanzania (2008)
Journal Article
Fillinger, U., Kannady, K., William, G., Vanek, M., Dongus, S., Nyika, D., …Killeen, G. (2008). A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Program in Dar es Salaam, Tanzania. Malaria Journal, 7, Article 20. https://doi.org/10.1186/1475-2875-7-20

Background: As the population of Africa rapidly urbanizes, large populations could be protected from malaria by controlling aquatic stages of mosquitoes if cost-effective and scalable implementation systems can be designed. Methods: A recently initia... Read More about A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Program in Dar es Salaam, Tanzania.

Suitability of two carbon dioxide-baited traps for mosquito surveillance in the United Kingdom. (2007)
Journal Article
Hutchinson, R., West, P., & Lindsay, S. (2007). Suitability of two carbon dioxide-baited traps for mosquito surveillance in the United Kingdom. Bulletin of Entomological Research, 97(6), 591-597. https://doi.org/10.1017/s0007485307005263

Rapidly changing environments and an increase in human movement around the globe have contributed to a rise in new and emerging diseases, many of which are arthropod borne. The threat posed to the United Kingdom by such diseases is uncertain, and the... Read More about Suitability of two carbon dioxide-baited traps for mosquito surveillance in the United Kingdom..

Interdependence of domestic malaria prevention measures and mosquito-human interactions in urban Dar es Salaam, Tanzania (2007)
Journal Article
Geissbühler, Y., Chaki, P., Emidi, B., Govella, N., Shirima, R., Mayagaya, V., …Killeen, G. (2007). Interdependence of domestic malaria prevention measures and mosquito-human interactions in urban Dar es Salaam, Tanzania. Malaria Journal, 6, Article 126. https://doi.org/10.1186/1475-2875-6-126

Background: Successful malaria vector control depends on understanding behavioural interactions between mosquitoes and humans, which are highly setting-specific and may have characteristic features in urban environments. Here mosquito biting patterns... Read More about Interdependence of domestic malaria prevention measures and mosquito-human interactions in urban Dar es Salaam, Tanzania.

Microbial larvicides for malaria control in The Gambia (2007)
Journal Article
Majambere, S., Lindsay, S., Green, C., Kandeh, B., & Fillinger, U. (2007). Microbial larvicides for malaria control in The Gambia. Malaria Journal, 6, Article 76. https://doi.org/10.1186/1475-2875-6-76

Background: Mosquito larval control may prove to be an effective tool for incorporating into integrated vector management (IVM) strategies for reducing malaria transmission. Here the efficacy of microbial larvicides against Anopheles gambiae s.l. was... Read More about Microbial larvicides for malaria control in The Gambia.

High spatial resolution mapping of malaria transmission risk in The Gambia, West Africa, using LANDSAT TM satellite imagery. (2007)
Journal Article
Bogh, C., Lindsay, S., Clarke, S., Dean, A., Jawara, M., Pinder, M., & Thomas, C. (2007). High spatial resolution mapping of malaria transmission risk in The Gambia, West Africa, using LANDSAT TM satellite imagery. American Journal of Tropical Medicine and Hygiene, 76(5), 875-881

Understanding local variability in malaria transmission risk is critically important when designing intervention or vaccine trials. Using a combination of field data, satellite image analysis, and GIS modeling, we developed a high-resolution map of m... Read More about High spatial resolution mapping of malaria transmission risk in The Gambia, West Africa, using LANDSAT TM satellite imagery..

Suppression of exposure to malaria vectors by an order of magnitude using microbial larvicides in rural Kenya (2006)
Journal Article
Fillinger, U., & Lindsay, S. (2006). Suppression of exposure to malaria vectors by an order of magnitude using microbial larvicides in rural Kenya. Tropical Medicine and International Health, 11(11), 1629-1642. https://doi.org/10.1111/j.1365-3156.2006.01733.x

Objective  To determine the contribution larviciding could make to reduce the burden of malaria, by conducting a trial of microbial larvicides in a 4.5 km2 area in and around a large village in rural western Kenya. Method  The abundance of immature a... Read More about Suppression of exposure to malaria vectors by an order of magnitude using microbial larvicides in rural Kenya.

Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania (2006)
Journal Article
Vanek, M., Shoo, B., Mtasiwa, D., Kiama, M., Lindsay, S., Fillinger, U., …Killeen, G. (2006). Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania. BMC Public Health, 6, Article 154. https://doi.org/10.1186/1471-2458-6-154

Background: As the population of Africa rapidly urbanizes it may be possible to protect large populations from malaria by controlling aquatic stages of mosquitoes. Here we present a baseline evaluation of the ability of community members to detect mo... Read More about Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania.

Culturally-compelling strategies for behaviour change. A social ecology model and case study in malaria prevention (2006)
Journal Article
Panter-Brick, C., Clarke, S., Lomas, H., Pinder, M., & Lindsay, S. (2006). Culturally-compelling strategies for behaviour change. A social ecology model and case study in malaria prevention. Social Science & Medicine, 62(11), 2810-2825. https://doi.org/10.1016/j.socscimed.2005.10.009

Behaviour change is notoriously difficult to initiate and sustain, and the reasons why efforts to promote healthy behaviours fail are coming under increasing scrutiny. To be successful, health interventions should build on existing practices, skills... Read More about Culturally-compelling strategies for behaviour change. A social ecology model and case study in malaria prevention.

Perceived nuisance of mosquitoes on the Isle of Sheppey, Kent, UK. (2006)
Journal Article
Hutchinson, R., & Lindsay, S. (2006). Perceived nuisance of mosquitoes on the Isle of Sheppey, Kent, UK. Journal of Biosocial Science, 38(5), 707-712. https://doi.org/10.1017/s0021932005000994

Little is known about the biting nuisance of mosquitoes in the UK, despite the high numbers found in some locations. A telephone questionnaire survey was used to determine the perceived nuisance of biting insects on the Isle of Sheppey, Kent, a place... Read More about Perceived nuisance of mosquitoes on the Isle of Sheppey, Kent, UK..

Relationship between the intensity of exposure to malaria parasites and infection in the Usambara mountains, Tanzania (2006)
Journal Article
Bodker, R., Msangeni, H., Kisinza, W., & Lindsay, S. (2006). Relationship between the intensity of exposure to malaria parasites and infection in the Usambara mountains, Tanzania. American Journal of Tropical Medicine and Hygiene, 74(5), 716-723. https://doi.org/10.4269/ajtmh.2006.74.716

The relationship between exposure to Plasmodium falciparum malaria and parasite density and prevalence was studied in six communities along an altitude transect. Prevalence of parasitemia in children decreased by 5% for every 100 meter increase in al... Read More about Relationship between the intensity of exposure to malaria parasites and infection in the Usambara mountains, Tanzania.

Negative spatial association between lymphatic filariasis and malaria in West Africa. (2006)
Journal Article
Kelly-Hope, L., Diggle, P., Rowlingson, B., Gyapong, J., Kyelem, D., Coleman, M., …Molyneux, D. (2006). Negative spatial association between lymphatic filariasis and malaria in West Africa. Tropical Medicine and International Health, 11(2), 129-135. https://doi.org/10.1111/j.1365-3156.2005.01558.x

Objective To determine the relationship between human lymphatic filariasis, caused by Wuchereria bancrofti, and falciparum malaria, which are co-endemic throughout West Africa. Methods We used geographical information systems and spatial statistics t... Read More about Negative spatial association between lymphatic filariasis and malaria in West Africa..

Ecologists can enable communities to implement malaria vector control in Africa (2006)
Journal Article
Mukabana, W., Kannady, K., Kiama, G., Ijumba, J., Mathenge, E., Kiche, I., …Killeen, G. (2006). Ecologists can enable communities to implement malaria vector control in Africa. Malaria Journal, 5, Article 9. https://doi.org/10.1186/1475-2875-5-9

Background: Integrated vector management (IVM) for malaria control requires ecological skills that are very scarce and rarely applied in Africa today. Partnerships between communities and academic ecologists can address this capacity deficit, moderni... Read More about Ecologists can enable communities to implement malaria vector control in Africa.