Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion
(2014)
Journal Article
Defour, A., van der Meulen, J., Bhat, R., Bigot, A., Bashir, R., Nagaraju, K., & Jaiswal, J. (2014). Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion. Cell Death and Disease, 5(6), https://doi.org/10.1038/cddis.2014.272
Dysferlin deficiency compromises the repair of injured muscle, but the underlying cellular mechanism remains elusive. To study this phenomenon, we have developed mouse and human myoblast models for dysferlinopathy. These dysferlinopathic myoblasts un... Read More about Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion.