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All Outputs (5)

An overview of cancer treatments (2009)
Journal Article
Anderson, R., Groundwater, P., Todd, A., & Moore, A. (2009). An overview of cancer treatments. Pharmaceutical journal (1933), 283, 511-512

The first of four articles on cancer treatments. This article provides an overview of traditional anticancer therapies, their mechanisms of action and their limitations.

The technology and techniques used in the detection of pathogenic bacteria (2009)
Journal Article
Groundwater, P., Todd, A., Worsley, A., & Anderson, R. (2009). The technology and techniques used in the detection of pathogenic bacteria. Pharmaceutical journal (1933), 283(7569), 281-282

In the light of requirements from the Care Quality Commission for hospitals to screen for and/or detect a range of micro-organisms including MRSA and C difficile, this article briefly reviews some techniques used for bacteraemia surveillance. In addi... Read More about The technology and techniques used in the detection of pathogenic bacteria.

Rational drug design — identifying and characterising a target (2009)
Journal Article
Todd, A., Anderson, R., & Groundwater, P. (2009). Rational drug design — identifying and characterising a target. Pharmaceutical journal (1933), 283(7559), 19-20

Structure-based drug design is now a common method used by the pharmaceutical industry to identify a lead compound and take it forward for further development. This article describes the methods used to identify and characterise a target for structur... Read More about Rational drug design — identifying and characterising a target.

Rational drug design — designing a molecule that binds to a target (2009)
Journal Article
Todd, A., Anderson, R., & Groundwater, P. (2009). Rational drug design — designing a molecule that binds to a target. Pharmaceutical journal (1933), 283(7563), 131-132

The second part of an article on rational drug design describes how a molecule that binds to a target is designed, using angiotensin-converting enzyme as an example to illustrate the process.