All Outputs (5)

Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine (2005)
Journal Article
Baron, A., Sandford, G., Slater, R., Yufit, D., Howard, J., & Vong, A. (2005). Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine. Journal of Organic Chemistry, 70(23), 9377-9381. https://doi.org/10.1021/jo051453v

Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds can be synthesized by sequential reaction of pentafluoropyridine with sodium phenylsulfinate and an appropriate diamine. The polyfunctionality possessed by the difluorinated tetrahydropyrido[2,... Read More about Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine.

Tetrahydropyrido 3,4-b pyrazine scaffolds from pentafluoropyridine (2005)
Journal Article
Sandford, G., Slater, R., Yufit, D., Howard, J., & Vong, A. (2005). Tetrahydropyrido 3,4-b pyrazine scaffolds from pentafluoropyridine. Journal of Organic Chemistry, 70(18), 7208-7216. https://doi.org/10.1021/jo0508696

Representative polyfunctional tetrahydropyrido[3,4-b]pyrazine scaffolds have been synthesized very readily by a one-pot annelation reaction of pentafluoropyridine with appropriate diamines. The trifluorinated pyridopyrazine products react sequentiall... Read More about Tetrahydropyrido 3,4-b pyrazine scaffolds from pentafluoropyridine.

Elemental fluorine - Part 18. Selective direct fluorination of 1,3-ketoesters and 1,3-diketones using gas/liquid microreactor technology (2005)
Journal Article
Chambers, R., Fox, M., & Sandford, G. (2005). Elemental fluorine - Part 18. Selective direct fluorination of 1,3-ketoesters and 1,3-diketones using gas/liquid microreactor technology. Lab on a Chip, 5(10), 1132-1139. https://doi.org/10.1039/b504675k

1,3-Ketoesters and 1,3-diketones react with fluorine gas, using Durham multichannel modular microreactor technology, on a preparatively useful scale. High conversions and yields of monofluorinated products were obtained. A consideration of the mechan... Read More about Elemental fluorine - Part 18. Selective direct fluorination of 1,3-ketoesters and 1,3-diketones using gas/liquid microreactor technology.

Versatile gas/liquid microreactors for industry (2005)
Journal Article
Chambers, R., Fox, M., Holling, D., Nakano, T., Okazoe, T., & Sandford, G. (2005). Versatile gas/liquid microreactors for industry. Chemical Engineering & Technology, 28(3), 344-352. https://doi.org/10.1002/ceat.200407123

The design, fabrication, use and scale-out of versatile, multi-channel gas/liquid microreactors, which are suitable for both laboratory and industrial syntheses, are described. Direct fluorination reactions of diethyl malonate and Meldrum's acid usin... Read More about Versatile gas/liquid microreactors for industry.

Elemental fluorine - Part 16. Versatile thin-film gas-liquid multi-channel microreactors for effective scale-out (2005)
Journal Article
Chambers, R., Fox, M., Holling, D., Nakano, T., Okazoe, T., & Sandford, G. (2005). Elemental fluorine - Part 16. Versatile thin-film gas-liquid multi-channel microreactors for effective scale-out. Lab on a Chip, 5(2), 191-198. https://doi.org/10.1039/b416400h

Versatile and conveniently operated microreactor devices, suitable for long term chemical synthesis for both laboratory and industrial use, are described. Direct fluorination of ethyl acetoacetate by fluorine gas is used as a model reaction to illust... Read More about Elemental fluorine - Part 16. Versatile thin-film gas-liquid multi-channel microreactors for effective scale-out.