All Outputs (3)

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. (2000)
Journal Article
Chen, Y., Cann, M., Litvin, T., Iourgenko, V., Sinclair, M., Levin, L., & Buck, J. (2000). Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science, 289(5479), 625-628. https://doi.org/10.1126/science.289.5479.625

Spermatozoa undergo a poorly understood activation process induced by bicarbonate and mediated by cyclic adenosine 3′,5′-monophosphate (cAMP). It has been assumed that bicarbonate mediates its effects through changes in intracellular pH or membrane p... Read More about Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor..

A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster. (2000)
Journal Article
Cann, M., Chung, E., & Levin, L. (2000). A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster. Development Genes and Evolution, 210(4), 200-206. https://doi.org/10.1007/s004270050304

We describe the cloning and characterization of a new gene family of adenylyl cyclase related genes in Drosophila. The five adenylyl cyclase-like genes that define this family are clearly distinct from previously known adenylyl cyclases. One member f... Read More about A new family of adenylyl cyclase genes in the male germline of Drosophila melanogaster..

Restricted expression of a truncated adenylyl cyclase in the cephalic furrow of Drosophila melanogaster (2000)
Journal Article
Cann, M., & Levin, L. (2000). Restricted expression of a truncated adenylyl cyclase in the cephalic furrow of Drosophila melanogaster. Development Genes and Evolution, 210(1), 34-40. https://doi.org/10.1007/pl00008186

We have identified a novel isoform of adenylyl cyclase, DAC78C, in Drosophila melanogaster that encodes two structurally distinct proteins in a developmentally restricted manner. The protein corresponding to one transcript is potently activated by G... Read More about Restricted expression of a truncated adenylyl cyclase in the cephalic furrow of Drosophila melanogaster.