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All Outputs (109)

Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein (2024)
Journal Article
Birkholz, N., Kamata, K., Feussner, M., Wilkinson, M. E., Cuba Samaniego, C., Migur, A., Kimanius, D., Ceelen, M., Went, S. C., Usher, B., Blower, T. R., Brown, C. M., Beisel, C. L., Weinberg, Z., Fagerlund, R. D., Jackson, S. A., & Fineran, P. C. (2024). Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein. Nature, 631(8021), 670-677. https://doi.org/10.1038/s41586-024-07644-1

In all organisms, regulation of gene expression must be adjusted to meet cellular requirements and frequently involves helix–turn–helix (HTH) domain proteins1. For instance, in the arms race between bacteria and bacteriophages, rapid expression of ph... Read More about Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein.

Editorial- Launching Enhancing Learning & Teaching in Higher Education (ELTHE): a place to publish and share your own scholarly work and teaching innovations. (2024)
Journal Article
Roger, M., & Nolan, S. (2024). Editorial- Launching Enhancing Learning & Teaching in Higher Education (ELTHE): a place to publish and share your own scholarly work and teaching innovations. Enhancing Teaching and Learning in Higher Education, 1, 1-3. https://doi.org/10.62512/etlhe.13

Welcome to the first edition of Enhancing Teaching and Learning in Higher Education (ELTHE). ETLHE offers an opportunity for those involved in universitylearning and teaching to disseminate their practice. It aims to publish accounts of scho... Read More about Editorial- Launching Enhancing Learning & Teaching in Higher Education (ELTHE): a place to publish and share your own scholarly work and teaching innovations..

Finding Transition State and Minimum Energy Path of Bistable Elastic Continua through Energy Landscape Explorations (2024)
Journal Article
Wan, G., Avis, S. J., Wang, Z., Wang, X., Kusumaatmaja, H., & Zhang, T. (2024). Finding Transition State and Minimum Energy Path of Bistable Elastic Continua through Energy Landscape Explorations. Journal of the Mechanics and Physics of Solids, 183, Article 105503. https://doi.org/10.1016/j.jmps.2023.105503

Mechanical bistable structures have two stable equilibria and can transit between them under external stimuli. Due to their unique behaviors such as snap-through and substantial shape changes, bistable structures exhibit unprecedented properties comp... Read More about Finding Transition State and Minimum Energy Path of Bistable Elastic Continua through Energy Landscape Explorations.

Multi-layered genome defences in bacteria (2024)
Journal Article
Agapov, A., Baker, K., Bedekar, P., Bhatia, R., Blower, T. R., Brockhurst, M. A., …Wright, R. (2024). Multi-layered genome defences in bacteria. Current Opinion in Microbiology, 78, Article 102436. https://doi.org/10.1016/j.mib.2024.102436

Bacteria have evolved a variety of defence mechanisms to protect against mobile genetic elements, including restriction-modification systems and CRISPR–Cas. In recent years, dozens of previously unknown defence systems (DSs) have been discovered. Not... Read More about Multi-layered genome defences in bacteria.

Scanning for dark matter subhaloes in Hubble Space Telescope imaging of 54 strong lenses (2023)
Journal Article
Nightingale, J. W., He, Q., Cao, X., Amvrosiadis, A., Etherington, A., Frenk, C. S., Hayes, R. G., Robertson, A., Cole, S., Lange, S., Li, R., & Massey, R. (2024). Scanning for dark matter subhaloes in Hubble Space Telescope imaging of 54 strong lenses. Monthly Notices of the Royal Astronomical Society, 527(4), 10480-10506. https://doi.org/10.1093/mnras/stad3694

The cold dark matter (DM) model predicts that every galaxy contains thousands of DM subhaloes; almost all other DM models include a physical process that smooths away the subhaloes. The subhaloes are invisible, but could be detected via strong gravit... Read More about Scanning for dark matter subhaloes in Hubble Space Telescope imaging of 54 strong lenses.

Diverse Durham collection phages demonstrate complex BREX defence responses (2023)
Journal Article
Kelly, A., Went, S. C., Mariano, G., Shaw, L. P., Picton, D. M., Duffner, S. J., Coates, I., Herdman-Grant, R., Gordeeva, J., Drobiazko, A., Isaev, A., Lee, Y.-J., Luyten, Y., Morgan, R. D., Weigele, P., Severinov, K., Wenner, N., Hinton, J. C., & Blower, T. R. (2023). Diverse Durham collection phages demonstrate complex BREX defence responses. Applied and Environmental Microbiology, https://doi.org/10.1128/aem.00623-23

Bacteriophages (phages) outnumber bacteria ten-to-one and cause infections at a rate of 1025 per second. The ability of phages to reduce bacterial populations makes them attractive alternative antibacterials for use in combating the rise in antimicro... Read More about Diverse Durham collection phages demonstrate complex BREX defence responses.

Going round in circles: Geometry in the early years (2023)
Journal Article
Oughton, R. H., Wheadon, D. M., Bolden, D. S., Nichols, K., Fearn, S., Darwin, S., …Townsend, A. (2023). Going round in circles: Geometry in the early years. Mathematics teaching, 286, 29-34

The research described here came from a collaboration between university-based mathematicians and early years (EY) educators. The project emerged naturally, driven by the felt need of the EY educators to develop a broader understanding and appreciati... Read More about Going round in circles: Geometry in the early years.

Extensive Polymorphism in the Molecular Ferroelectric 18-Crown-6 Oxonium Tetrachloro-Gallium(III) (2023)
Journal Article
Thompson, S. Y., Devenney, L. A., Yufit, D. S., & Evans, J. S. (2023). Extensive Polymorphism in the Molecular Ferroelectric 18-Crown-6 Oxonium Tetrachloro-Gallium(III). Crystal Growth and Design, 23(4), 2860-2869. https://doi.org/10.1021/acs.cgd.3c00017

The materials property of ferroelectricity is intimately linked with symmetry-changing phase transitions. Characterizing such transitions is therefore essential for understanding molecular ferroelectrics. In this paper, we explore the temperature and... Read More about Extensive Polymorphism in the Molecular Ferroelectric 18-Crown-6 Oxonium Tetrachloro-Gallium(III).

Beyond the bulge–halo conspiracy? Density profiles of early-type galaxies from extended-source strong lensing (2023)
Journal Article
Etherington, A., Nightingale, J. W., Massey, R., Robertson, A., Cao, X., Amvrosiadis, A., Cole, S., Frenk, C. S., He, Q., Lagattuta, D. J., Lange, S., & Li, R. (2023). Beyond the bulge–halo conspiracy? Density profiles of early-type galaxies from extended-source strong lensing. Monthly Notices of the Royal Astronomical Society, 521(4), 6005-6018. https://doi.org/10.1093/mnras/stad582

Observations suggest that the dark matter and stars in early-type galaxies ‘conspire’ to produce a surprisingly simple distribution of total mass, ρ(r) ∝ ρ−γ, with γ ≈ 2. We measure the distribution of mass in 48 early-type galaxies that gravitationa... Read More about Beyond the bulge–halo conspiracy? Density profiles of early-type galaxies from extended-source strong lensing.

PyAutoGalaxy: Open-Source Multiwavelength Galaxy Structure & Morphology (2023)
Journal Article
Nightingale, J. W., Amvrosiadis, A., Hayes, R. G., He, Q., Etherington, A., Cao, X., …Robertson, A. (2023). PyAutoGalaxy: Open-Source Multiwavelength Galaxy Structure & Morphology. The Journal of Open Source Software, 8(81), Article 4475. https://doi.org/10.21105/joss.04475

Nearly a century ago, Edwin Hubble famously classified galaxies into three distinct groups: ellipticals, spirals and irregulars (Hubble, 1926). Today, by analysing millions of galaxies with advanced image processing techniques Astronomers have expand... Read More about PyAutoGalaxy: Open-Source Multiwavelength Galaxy Structure & Morphology.

Utilising online eye-tracking to discern the impacts of cultural backgrounds on fake and real news decision-making (2022)
Journal Article
Brockinton, A., Hirst, S., Wang, R., McAlaney, J., & Thompson, S. (2022). Utilising online eye-tracking to discern the impacts of cultural backgrounds on fake and real news decision-making. Frontiers in Psychology, 13, Article 999780. https://doi.org/10.3389/fpsyg.2022.999780

Introduction: Online eye-tracking has been used in this study to assess the impacts of different cultural backgrounds on information discernment. An online platform called RealEye allowed participants to engage in the eye-tracking study from their pe... Read More about Utilising online eye-tracking to discern the impacts of cultural backgrounds on fake and real news decision-making.

A robust and memory-efficient transition state search method for complex energy landscapes (2022)
Journal Article
Avis, S. J., Panter, J. R., & Kusumaatmaja, H. (2022). A robust and memory-efficient transition state search method for complex energy landscapes. The Journal of Chemical Physics, 157(12), Article 124107. https://doi.org/10.1063/5.0102145

Locating transition states is crucial for investigating transition mechanisms in wide-ranging phenomena, from atomistic to macroscale systems. Existing methods, however, can struggle in problems with a large number of degrees of freedom, on-the-fly a... Read More about A robust and memory-efficient transition state search method for complex energy landscapes.

A Collaboratively-Derived Research Agenda for E-assessment in Undergraduate Mathematics (2022)
Journal Article
Kinnear, G., Jones, I., Sangwin, C., Alarfaj, M., Davies, B., Fearn, S., …Wong, T. (2022). A Collaboratively-Derived Research Agenda for E-assessment in Undergraduate Mathematics. International Journal of Research in Undergraduate Mathematics Education, https://doi.org/10.1007/s40753-022-00189-6

This paper describes the collaborative development of an agenda for research on e-assessment in undergraduate mathematics. We built on an established approach to develop the agenda from the contributions of 22 mathematics education researchers, unive... Read More about A Collaboratively-Derived Research Agenda for E-assessment in Undergraduate Mathematics.

Developing ‘deep mathematical thinking’ in geometry with 3- and 4-year-olds: A collaborative study between early years teachers and University-based mathematicians (2022)
Journal Article
Oughton, R., Nichols, K., Bolden, D. S., Dixon-Jones, S., Fearn, S., Darwin, S., …Townsend, A. (2022). Developing ‘deep mathematical thinking’ in geometry with 3- and 4-year-olds: A collaborative study between early years teachers and University-based mathematicians. Mathematical Thinking and Learning, https://doi.org/10.1080/10986065.2022.2119497

Mathematics in early years settings is often restricted to learning to count and identifying simple shapes. This is partly due to the narrow scope of many early years curricula and insufficient teacher training for exploring deeper mathematical conce... Read More about Developing ‘deep mathematical thinking’ in geometry with 3- and 4-year-olds: A collaborative study between early years teachers and University-based mathematicians.

Tailoring the multistability of origami-inspired, buckled magnetic structures via compression and creasing (2021)
Journal Article
Li, Y., Avis, S. J., Zhang, T., Kusumaatmaja, H., & Wang, X. (2021). Tailoring the multistability of origami-inspired, buckled magnetic structures via compression and creasing. Materials Horizons, 8(12), 3324-3333. https://doi.org/10.1039/d1mh01152a

Origami-inspired multistable structures are gaining increasing interest because of their potential applications in fields ranging from deployable structures to reconfigurable microelectronics. The multistability of such structures is critical for the... Read More about Tailoring the multistability of origami-inspired, buckled magnetic structures via compression and creasing.

Reconfiguration of multistable 3D ferromagnetic mesostructures guided by energy landscape surveys (2021)
Journal Article
Li, Y., Avis, S. J., Chen, J., Wu, G., Zhang, T., Kusumaatmaja, H., & Wang, X. (2021). Reconfiguration of multistable 3D ferromagnetic mesostructures guided by energy landscape surveys. Extreme Mechanics Letters, 48, Article 101428. https://doi.org/10.1016/j.eml.2021.101428

Three-dimensional (3D) mesostructures that can reversibly change their geometries and thereby their functionalities are promising for a wide range of applications. Despite intensive studies, the lack of fundamental understanding of the highly nonline... Read More about Reconfiguration of multistable 3D ferromagnetic mesostructures guided by energy landscape surveys.

Predicting Hemiwicking Dynamics on Textured Substrates (2020)
Journal Article
Natarajan, B., Jaishankar, A., King, M., Oktasendra, F., Avis, S. J., Konicek, A. R., …Yeganeh, M. S. (2021). Predicting Hemiwicking Dynamics on Textured Substrates. Langmuir, 37(1), 188-195. https://doi.org/10.1021/acs.langmuir.0c02737

The ability to predict liquid transport rates on textured surfaces is key to the design and optimization of devices and processes such as oil recovery, coatings, reaction-separation, high-throughput screening, and thermal management. In this work we... Read More about Predicting Hemiwicking Dynamics on Textured Substrates.

OpenLB—Open source lattice Boltzmann code (2020)
Journal Article
Krause, M. J., Kummerländer, A., Avis, S. J., Kusumaatmaja, H., Dapelo, D., Klemens, F., …Simonis, S. (2021). OpenLB—Open source lattice Boltzmann code. Computers and Mathematics with Applications, 81, 258-288. https://doi.org/10.1016/j.camwa.2020.04.033

We present the OpenLB package, a C++ library providing a flexible framework for lattice Boltzmann simulations. The code is publicly available and published under GNU GPLv2, which allows for adaption and implementation of additional models. The extens... Read More about OpenLB—Open source lattice Boltzmann code.