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Trap induced broadening in a potential hydrogen lattice clock (2024)
Journal Article
Scott, J. P., Potvliege, R. M., Carty, D., & Jones, M. P. A. (2024). Trap induced broadening in a potential hydrogen lattice clock. Metrologia, 61(2), Article 025001. https://doi.org/10.1088/1681-7575/ad1e37

We consider the potential use of optical traps for precision measurements in atomic hydrogen (H). Using an implicit summation method, we calculate the atomic polarisability, the rates of elastic/inelastic scattering and the ionisation rate in the wav... Read More about Trap induced broadening in a potential hydrogen lattice clock.

Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes (2023)
Journal Article
De Rosa, D. F., Starck, M., Parker, D., & Pal, R. (2024). Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes. Chemistry - A European Journal, 30(9), Article e202303227. https://doi.org/10.1002/chem.202303227

Understanding the factors that shape the circularly polarised luminescence (CPL) emission profiles of europium(III)-based CPL emitters to have specific sign properties, e. g. monosignate individual CPL transitions, is key to design novel complexes fo... Read More about Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes.

Monitoring wader breeding productivity (2023)
Journal Article
Jarrett, D., Lehikoinen, A., & Willis, S. (2023). Monitoring wader breeding productivity. Ibis: International Journal of Avian Science, https://doi.org/10.1111/ibi.13298

A robust understanding of the mechanisms driving demographic change in wild animal populations is fundamental to the delivery of effective conservation interventions. Demographic change can be driven by variation in adult survival, recruitment of juv... Read More about Monitoring wader breeding productivity.

Soil–Water Retention Curve Prediction for Compacted London Clay Subjected to Moisture Cycles (2023)
Journal Article
Dias, A. S., Hughes, P. N., & Toll, D. G. (2024). Soil–Water Retention Curve Prediction for Compacted London Clay Subjected to Moisture Cycles. Geotechnical and Geological Engineering, 42(4), 2799-2814. https://doi.org/10.1007/s10706-023-02706-z

The evolution of the hydraulic properties of London Clay when compacted at a range of initial conditions (density and water content) was investigated. The soil–water retention curve (SWRC) is observed to change as the soil is subjected to cycles of w... Read More about Soil–Water Retention Curve Prediction for Compacted London Clay Subjected to Moisture Cycles.

A simple method to determine soil–water retention curves of compacted active clays (2023)
Journal Article
Dias, A. S., Hughes, P. N., Toll, D. G., & Glendinning, S. (2023). A simple method to determine soil–water retention curves of compacted active clays. Transportation Geotechnics, 43, 101138. https://doi.org/10.1016/j.trgeo.2023.101138

Determining the Soil Water Retention Curve (SWRC) of an active clay constitutes a challenge due to the significant, and sometimes irreversible, volume changes that occur during wetting and drying cycles. A novel yet simple method of experimentally de... Read More about A simple method to determine soil–water retention curves of compacted active clays.

Diverse Durham collection phages demonstrate complex BREX defence responses (2023)
Journal Article
Kelly, A., Went, S. C., Mariano, G., Shaw, L. P., Picton, D. M., Duffner, S. J., Coates, I., Herdman-Grant, R., Gordeeva, J., Drobiazko, A., Isaev, A., Lee, Y.-J., Luyten, Y., Morgan, R. D., Weigele, P., Severinov, K., Wenner, N., Hinton, J. C., & Blower, T. R. (2023). Diverse Durham collection phages demonstrate complex BREX defence responses. Applied and Environmental Microbiology, https://doi.org/10.1128/aem.00623-23

Bacteriophages (phages) outnumber bacteria ten-to-one and cause infections at a rate of 1025 per second. The ability of phages to reduce bacterial populations makes them attractive alternative antibacterials for use in combating the rise in antimicro... Read More about Diverse Durham collection phages demonstrate complex BREX defence responses.

An Evolutionary Neural Network Approach for Slopes Stability Assessment (2023)
Journal Article
Tinoco, J., Gomes Correia, A., Cortez, P., & Toll, D. (2023). An Evolutionary Neural Network Approach for Slopes Stability Assessment. Applied Sciences, 13(14), Article 8084. https://doi.org/10.3390/app13148084

A current big challenge for developed or developing countries is how to keep large-scale transportation infrastructure networks operational under all conditions. Network extensions and budgetary constraints for maintenance purposes are among the main... Read More about An Evolutionary Neural Network Approach for Slopes Stability Assessment.

MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control (2023)
Journal Article
Thompson, H., Shen, W., Matus, R., Kakkar, M., Jones, C., Dolan, D., …Lindsey, K. (2023). MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control. Development, 150(7), Article dev201476. https://doi.org/10.1242/dev.201476

Plants respond to environmental stresses through controlled stem cell maintenance and meristem activity. One level of gene regulation is RNA alternative splicing. However, the mechanistic link between stress, meristem function and RNA splicing is poo... Read More about MERISTEM-DEFECTIVE regulates the balance between stemness and differentiation in the root meristem through RNA splicing control.

Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields (2023)
Journal Article
Maity, S., Price, B. D., Wilson, C. B., Mukherjee, A., Starck, M., Parker, D., Wilson, M. Z., Lovett, J. E., Han, S., & Sherwin, M. S. (2023). Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields. Angewandte Chemie International Edition, 62(13), Article e202212832. https://doi.org/10.1002/anie.202212832

We present time-resolved Gd−Gd electron paramagnetic resonance (TiGGER) at 240 GHz for tracking inter-residue distances during a protein's mechanical cycle in the solution state. TiGGER makes use of Gd-sTPATCN spin labels, whose favorable qualities i... Read More about Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields.

Bullseye Analysis: A Fluorescence Microscopy Technique to Detect Local Changes in Intracellular Reactive Oxygen Species (ROS) Production (2022)
Journal Article
Hughes, J. G., Chisholm, D. R., Whiting, A., Girkin, J. M., & Ambler, C. A. (2023). Bullseye Analysis: A Fluorescence Microscopy Technique to Detect Local Changes in Intracellular Reactive Oxygen Species (ROS) Production. Microscopy and Microanalysis, 29(2), 529-539. https://doi.org/10.1093/micmic/ozac040

Reactive oxygen species (ROS) are naturally produced compounds that play important roles in cell signaling, gene regulation, and biological defense, including involvement in the oxidative burst that is central to the anti-microbial actions of macroph... Read More about Bullseye Analysis: A Fluorescence Microscopy Technique to Detect Local Changes in Intracellular Reactive Oxygen Species (ROS) Production.

The bounding effect of the water retention curve on the cyclic response of an unsaturated soil (2022)
Journal Article
Azizi, A., Kumar, A., & Toll, D. G. (2023). The bounding effect of the water retention curve on the cyclic response of an unsaturated soil. Acta Geotechnica, 18(4), 1901-1917. https://doi.org/10.1007/s11440-022-01724-0

The water retention properties of soils present in formation layers of roads and railways continuously vary due to repeated traffic loads and periodic rainfall events. This is important because the accumulated deformation and resilient modulus of suc... Read More about The bounding effect of the water retention curve on the cyclic response of an unsaturated soil.

Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification (2022)
Journal Article
Fradgley, J. D., Starck, M., Lamarque, L., & Parker, D. (2022). Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification. European Journal of Inorganic Chemistry, 2022(32), Article e202200426. https://doi.org/10.1002/ejic.202200426

The synthesis and photophysical evaluation of a series of hydrophilic sulphonated and pH responsive luminescent europium(III) probes are reported. The Eu emission intensities and lifetimes increase very significantly on lowering pH, leading to a ‘swi... Read More about Comparative Analysis of a Series of pH‐Responsive Sulphonated Europium Complexes for Bioassays Monitoring Acidification.

Versatile, Cheap, Readily Modifiable Sample Delivery Method for Analysis of Air-/Moisture-Sensitive Samples Using Atmospheric Pressure Solids Analysis Probe Mass Spectrometry (2022)
Journal Article
Strong, K. A., Stokes, P., Parker, D., Buckley, A. K., Mosely, J. A., Brodie, C. N., & Dyer, P. W. (2022). Versatile, Cheap, Readily Modifiable Sample Delivery Method for Analysis of Air-/Moisture-Sensitive Samples Using Atmospheric Pressure Solids Analysis Probe Mass Spectrometry. Analytical Chemistry, 94(32), 11315-11320. https://doi.org/10.1021/acs.analchem.2c02039

A cheap, versatile, readily modified, and reusable glass probe system enabling delivery of solid air-/moisture-sensitive samples for mass spectrometric (MS) analysis using an Atmospheric pressure Solids Analysis Probe (ASAP) is described. The simplic... Read More about Versatile, Cheap, Readily Modifiable Sample Delivery Method for Analysis of Air-/Moisture-Sensitive Samples Using Atmospheric Pressure Solids Analysis Probe Mass Spectrometry.

An investigation of the combined effect of rainfall and road cut on landsliding (2022)
Journal Article
Pradhan, S., Toll, D., Rosser, N., & Brain, M. (2022). An investigation of the combined effect of rainfall and road cut on landsliding. Engineering Geology, 307, Article 106787. https://doi.org/10.1016/j.enggeo.2022.106787

The reduction of soil suction and consequent loss of shear strength due to infiltration is known to trigger shallow landslides during periods of concentrated rainfall. In the mountainous terrain of Nepal, the risk of shallow rainfall-induced landslid... Read More about An investigation of the combined effect of rainfall and road cut on landsliding.

Crystal structure of the BREX phage defence protein BrxA (2022)
Journal Article
Beck, I., Picton, D., & Blower, T. (2022). Crystal structure of the BREX phage defence protein BrxA. Current Research in Structural Biology, https://doi.org/10.1016/j.crstbi.2022.06.001

Bacteria are constantly challenged by bacteriophage (phage) infection and have developed multitudinous and varied resistance mechanisms. Bacteriophage Exclusion (BREX) systems protect from phage infection by generating methylation patterns at non-pal... Read More about Crystal structure of the BREX phage defence protein BrxA.

A widespread family of WYL-domain transcriptional regulators co-localises with diverse phage defence systems and islands (2022)
Journal Article
Picton, D., Harling-Lee, J., Duffner, S., Went, S., Morgan, R., Hinton, J., & Blower, T. (2022). A widespread family of WYL-domain transcriptional regulators co-localises with diverse phage defence systems and islands. Nucleic Acids Research, 50(9), 5191-5207. https://doi.org/10.1093/nar/gkac334

Bacteria are under constant assault by bacteriophages and other mobile genetic elements. As a result, bacteria have evolved a multitude of systems that protect from attack. Genes encoding bacterial defence mechanisms can be clustered into “defence is... Read More about A widespread family of WYL-domain transcriptional regulators co-localises with diverse phage defence systems and islands.

Reusing Fe water treatment residual as a soil amendment to improve physical function and flood resilience (2022)
Journal Article
Kerr, H. C., Johnson, K. L., & Toll, D. G. (2022). Reusing Fe water treatment residual as a soil amendment to improve physical function and flood resilience. SOIL, 8(1), 283-295. https://doi.org/10.5194/soil-8-283-2022

Soil degradation is a global challenge that is intrinsically linked to climate change and food security. Soil degradation has many causes, but all degraded soils suffer from poor soil structure. The increasing global production of water treatment res... Read More about Reusing Fe water treatment residual as a soil amendment to improve physical function and flood resilience.

The mechanical properties of a high plasticity expansive clay (2022)
Journal Article
Gaspar, T., Jacobsz, S., Heymann, G., Toll, D., Gens, A., & Osman, A. (2022). The mechanical properties of a high plasticity expansive clay. Engineering Geology, 303, https://doi.org/10.1016/j.enggeo.2022.106647

The mechanical properties of a high plasticity expansive clay from South Africa are reported. The experimental programme considered wetting after loading tests followed by one-dimensional consolidation and unloading of undisturbed and statically comp... Read More about The mechanical properties of a high plasticity expansive clay.