Sterically-controlled regioselective para-substitutions of aniline

Dyer, P.W.; Fawcett, J.; Griffith, G.A.; Hanton, M.J.; Olivier, C.; Patterson, A.R.; Suhard, S.

Abstract

Introduction of sterically demanding 1-isopropyl-2-methyl-propyl or triisopropylsilyl groups at the nitrogen of aniline allows high-yielding regioselective para-substitution to be achieved using a lithiation/substitution sequence.

Citation

Dyer, P., Fawcett, J., Griffith, G., Hanton, M., Olivier, C., Patterson, A., & Suhard, S. (2005). Sterically-controlled regioselective para-substitutions of aniline. Chemical Communications, 2005(30), 3835-3837. https://doi.org/10.1039/b506824j

• Journal Article Type: Article
• Acceptance Date: May 27, 2005
• Online Publication Date: Jun 24, 2005
• Publication Date: 2005
• Deposit Date: May 10, 2007
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 2005
• Issue: 30
• Pages: 3835-3837
• DOI: https://doi.org/10.1039/b506824j
• Public URL: https://durham-repository.worktribe.com/output/1602771