Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex

Congreve, A.; Parker, D.; Gianolio, E.; Botta, M.

Abstract

Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL(1)], bearing an N-linked CH2CH2NHCO-pyridyl moiety, forms mono-aqua (q = 1) species in solution and the Gd complex undergoes rapid water exchange (k(ex) = 11 x 10(7) s(-1), 298 K) as a result of the steric destabilisation of the Ln-water binding interaction. The homologous complex with a C-3 spacing chain, [LnL(2)], forms a q = 0 species.

Citation

Congreve, A., Parker, D., Gianolio, E., & Botta, M. (2004). Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide 'DOTA' complex. Dalton Transactions, 2004(9), 1441-1445. https://doi.org/10.1039/B402230K

• Journal Article Type: Article
• Online Publication Date: Apr 5, 2004
• Publication Date: 2004
• Journal: Dalton Transactions
• Print ISSN: 1477-9226
• Electronic ISSN: 1477-9234
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 2004
• Issue: 9
• Pages: 1441-1445
• DOI: https://doi.org/10.1039/B402230K
• Public URL: https://durham-repository.worktribe.com/output/1571343