A Preparative and Solution Study of a Modified b-Cyclodextrin and its Europium(III) Complex, and their Interactions with Racemic Amino Acid Anions.

Kean, S.D.; Easton, C.J.; Lincoln, S.F.; Parker, D.

Abstract

The synthesis and characterization of 6A-deoxy-6A-(1,4,7-tri(carboxylatomethyl)-1,4,7,10-tetraazacyclododecan-10-yl)-β-cyclodextrin (1b) are reported. A fluorescence lifetime study of its Eu3+ complex (1c) is consistent with one water coordinating Eu3+ in addition to hepta-coordination by (1b). 1H NMR studies are consistent with (1b) forming host–guest complexes with (R/S)-histidinate (2a), (R/S)-tyrosinate (2b), (R/S)-phenylalaninate (2c), and (R/S)-tryptophanate (2d), with enantioselectivity shown for (2b). Similar studies are consistent with (1c) complexing (2a–d), with enantioselectivity shown for (2a).

Citation

Kean, S., Easton, C., Lincoln, S., & Parker, D. (2001). A Preparative and Solution Study of a Modified b-Cyclodextrin and its Europium(III) Complex, and their Interactions with Racemic Amino Acid Anions. Australian Journal of Chemistry, 54(8), 535-539. https://doi.org/10.1071/ch01102

• Journal Article Type: Article
• Publication Date: 2001
• Journal: Australian Journal of Chemistry
• Print ISSN: 0004-9425
• Publisher: CSIRO Publishing
• Peer Reviewed: Peer Reviewed
• Volume: 54
• Issue: 8
• Pages: 535-539
• DOI: https://doi.org/10.1071/ch01102