W.C.E. Schofield
Rewritable DNA microarrays
Schofield, W.C.E.; McGettrick, J.; Bradley, T.J.; Badyal, J.P.S.; Przyborski, S.
Authors
Abstract
Thiol-terminated single-stranded deoxyribonucleic acids (ssDNA) can be immobilized onto pulsed plasma deposited poly(allylmercaptan) surfaces via disulfide bridge chemistry and are found to readily undergo nucleic acid hybridization. Unlike other methods for oligonucleotide attachment to solid surfaces, this approach is shown to be independent of substrate material or geometry, and amenable to highly efficient rewriting.
Citation
Schofield, W., McGettrick, J., Bradley, T., Badyal, J., & Przyborski, S. (2006). Rewritable DNA microarrays. Journal of the American Chemical Society, 128(7), 2280-2285. https://doi.org/10.1021/ja056367r
Journal Article Type | Article |
---|---|
Publication Date | Jan 1, 2006 |
Deposit Date | May 10, 2007 |
Journal | Journal of the American Chemical Society |
Print ISSN | 0002-7863 |
Electronic ISSN | 1520-5126 |
Publisher | American Chemical Society |
Peer Reviewed | Peer Reviewed |
Volume | 128 |
Issue | 7 |
Pages | 2280-2285 |
DOI | https://doi.org/10.1021/ja056367r |
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