Catalytic SNAr of unactivated aryl chlorides

Walton, JW; Williams, JMJ

Abstract

We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η6-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(II) complexes that lower the activation barrier to arene exchange.

Citation

Walton, J., & Williams, J. (2015). Catalytic SNAr of unactivated aryl chlorides. Chemical Communications, 51(14), 2786-2789. https://doi.org/10.1039/c4cc07116f

• Journal Article Type: Article
• Acceptance Date: Oct 6, 2014
• Online Publication Date: Oct 6, 2014
• Publication Date: Feb 18, 2015
• Deposit Date: Oct 17, 2014
• Publicly Available Date: Oct 21, 2014
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 51
• Issue: 14
• Pages: 2786-2789
• DOI: https://doi.org/10.1039/c4cc07116f
• Public URL: https://durham-repository.worktribe.com/output/1421676