Enantioselective cellular localisation of europium(iii) coordination complexes

Frawley, Andrew T.; Linford, Holly V.; Starck, Matthieu; Pal, Robert; Parker, David

Abstract

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

Citation

Frawley, A. T., Linford, H., Starck, M., Pal, R., & Parker, D. (2018). Enantioselective cellular localisation of europium(iii) coordination complexes. Chemical Science, 9(4), 1042-1049. https://doi.org/10.1039/c7sc04422d

• Journal Article Type: Article
• Acceptance Date: Dec 6, 2017
• Online Publication Date: Dec 6, 2017
• Publication Date: Jan 28, 2018
• Deposit Date: Feb 8, 2018
• Publicly Available Date: Feb 8, 2018
• Journal: Chemical Science
• Print ISSN: 2041-6520
• Electronic ISSN: 2041-6539
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 9
• Issue: 4
• Pages: 1042-1049
• DOI: https://doi.org/10.1039/c7sc04422d
• Public URL: https://durham-repository.worktribe.com/output/1367070