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Sustainable Flow Synthesis of a Versatile Cyclopentenone Building Block

Baumann, Marcus; Baxendale, Ian R.; Filipponi, Paolo; Hu, Te

Sustainable Flow Synthesis of a Versatile Cyclopentenone Building Block Thumbnail


Marcus Baumann

Paolo Filipponi

Te Hu


A flow based multistep processing sequence to reliably provide the delivery of a highly functional cyclopentenone is described. The exemplification of employing solid dosing of reagents and in-line aqueous extraction has enabled an integrated workflow in a highly automated reactor setup.

Journal Article Type Article
Acceptance Date Nov 20, 2017
Online Publication Date Nov 8, 2017
Publication Date Dec 15, 2017
Deposit Date Nov 20, 2017
Publicly Available Date Nov 8, 2018
Journal Organic Process Research and Development
Print ISSN 1083-6160
Electronic ISSN 1520-586X
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 21
Issue 12
Pages 2052-2059
Public URL


Accepted Journal Article (Supporting Information) (1.8 Mb)

Copyright Statement
Supporting Information

Accepted Journal Article (1.3 Mb)

Copyright Statement
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Process Research & Development, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see

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