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Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1

Cioffi, Christopher L.; Liu, Shuang; Wolf, Mark A.; Guzzo, Peter R.; Sadalapure, Kashinath; Parthasarathy, Visweswaran; Loong, David T.J.; Maeng, Jun-Ho; Carulli, Edmund; Fang, Xiao; Karunakaran, Kalesh; Matta, Lakshman; Choo, Sok Hui; Panduga, Shailijia; Buckle, Ronald N.; Davis, Randall N.; Sakwa, Samuel A.; Gupta, Priya; Sargent, Bruce J.; Moore, Nicholas A.; Luche, Michele M.; Carr, Grant J.; Khmelnitsky, Yuri L.; Ismail, Jiffry; Chung, Mark; Bai, Mei; Leong, Wei Yee; Sachdev, Nidhi; Swaminathan, Srividya; Mhyre, Andrew J.

Authors

Christopher L. Cioffi

Shuang Liu

Mark A. Wolf

Peter R. Guzzo

Kashinath Sadalapure

Visweswaran Parthasarathy

David T.J. Loong

Jun-Ho Maeng

Edmund Carulli

Xiao Fang

Lakshman Matta

Sok Hui Choo

Shailijia Panduga

Ronald N. Buckle

Randall N. Davis

Samuel A. Sakwa

Priya Gupta

Bruce J. Sargent

Nicholas A. Moore

Michele M. Luche

Grant J. Carr

Yuri L. Khmelnitsky

Jiffry Ismail

Mark Chung

Mei Bai

Wei Yee Leong

Nidhi Sachdev

Srividya Swaminathan

Andrew J. Mhyre



Citation

Cioffi, C. L., Liu, S., Wolf, M. A., Guzzo, P. R., Sadalapure, K., Parthasarathy, V., …Mhyre, A. J. (2016). Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1. Journal of Medicinal Chemistry, 59(18), 8473-8494. https://doi.org/10.1021/acs.jmedchem.6b00914

Journal Article Type Article
Online Publication Date Aug 25, 2016
Publication Date 2016-09
Deposit Date Jan 29, 2019
Journal Journal of Medicinal Chemistry
Print ISSN 0022-2623
Electronic ISSN 1520-4804
Publisher American Chemical Society
Peer Reviewed Peer Reviewed
Volume 59
Issue 18
Pages 8473-8494
DOI https://doi.org/10.1021/acs.jmedchem.6b00914

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