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Recent advances in the development of anti-infective peptoids

Bicker, Kevin L.; Cobb, Steven L

Recent advances in the development of anti-infective peptoids Thumbnail


Kevin L. Bicker


In the search for new sources of antimicrobials many researchers have investigated antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics. However, efforts to develop AMPs in this area has been severely hampered by their inherent susceptibility to enzymatic degradation. Given this only a handful of AMPs are currently in clinical trials. Peptide mimetics such as peptoids have emerged as highly promising alternatives to AMPs as they are inherently stable to enzymatic degradation and display potent antimicrobial properties. This feature article highlights the progress that has been made towards the development of novel anti-infective peptoids.


Bicker, K. L., & Cobb, S. L. (2020). Recent advances in the development of anti-infective peptoids. Chemical Communications, 56(76), 11158-11168.

Journal Article Type Article
Acceptance Date Aug 24, 2020
Online Publication Date Aug 28, 2020
Publication Date 2020-09
Deposit Date Oct 14, 2020
Publicly Available Date Aug 28, 2021
Journal Chemical Communications
Print ISSN 1359-7345
Electronic ISSN 1364-548X
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 56
Issue 76
Pages 11158-11168


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