Understanding the Interaction of Gluconamides and Gluconates with Amino Acids in Hair Care

Chambers, Luke I.; Yufit, Dmitry S.; Musa, Osama M.; Steed, Jonathan W.

Abstract

A hair care mixture formed from a gluconamide derivative and 3-hydroxypropyl ammonium gluconate is known to strengthen hair fibers; however, the mechanism by which the mixture affects hair is unknown. To give insight into the aggregation of the target gluconamide and potential interactions between the gluconate-derived mixture and hair fibers, a range of systems were characterized by X-ray crystallography namely two polymorphic forms of the target gluconamide and three salts of 3-hydroxypropylammonium with sulfuric acid, methane sulfonic acid, and oxalic acid. The gluconamide proves to aggregate and becomes a supramolecular gelator in aniline and benzyl alcohol solution. The resulting gels were characterized by rheology, scanning electron microscopy, proton nuclear magnetic resonance, Fourier transform infrared spectroscopy, and powder X-ray diffraction.

Citation

Chambers, L. I., Yufit, D. S., Musa, O. M., & Steed, J. W. (2022). Understanding the Interaction of Gluconamides and Gluconates with Amino Acids in Hair Care. Crystal Growth and Design, 22(10), 6190-6200. https://doi.org/10.1021/acs.cgd.2c00753

• Journal Article Type: Article
• Online Publication Date: Sep 20, 2022
• Publication Date: 2022
• Deposit Date: Oct 25, 2022
• Publicly Available Date: Oct 25, 2022
• Journal: Crystal Growth and Design
• Print ISSN: 1528-7483
• Electronic ISSN: 1528-7505
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 22
• Issue: 10
• Pages: 6190-6200
• DOI: https://doi.org/10.1021/acs.cgd.2c00753
• Public URL: https://durham-repository.worktribe.com/output/1187498