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Outputs (3760)

Ecologists can enable communities to implement malaria vector control in Africa (2006)
Journal Article
Mukabana, W., Kannady, K., Kiama, G., Ijumba, J., Mathenge, E., Kiche, I., …Killeen, G. (2006). Ecologists can enable communities to implement malaria vector control in Africa. Malaria Journal, 5, Article 9. https://doi.org/10.1186/1475-2875-5-9

Background: Integrated vector management (IVM) for malaria control requires ecological skills that are very scarce and rarely applied in Africa today. Partnerships between communities and academic ecologists can address this capacity deficit, moderni... Read More about Ecologists can enable communities to implement malaria vector control in Africa.

Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm (2006)
Journal Article
Weinkove, D., Halstead, J., Gems, D., & Divecha, N. (2006). Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm. BMC Biology, 4, Article 1. https://doi.org/10.1186/1741-7007-4-1

Background: The provision of stress resistance diverts resources from development and reproduction and must therefore be tightly regulated. In Caenorhabditis elegans, the switch to increased stress resistance to promote survival through periods of st... Read More about Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm.

Proteomic analysis of the heat shock response in Synechocystis PCC6803 and a thermally tolerant knockout strain lacking the histidine kinase34 gene (2006)
Journal Article
Slabas, A., Suzuki, I., Murata, N., Simon, J., & Hall, J. (2006). Proteomic analysis of the heat shock response in Synechocystis PCC6803 and a thermally tolerant knockout strain lacking the histidine kinase34 gene. Proteomics, 6(3), 845-864. https://doi.org/10.1002/pmic.200500196

Proteomic analysis of the heat shock response of wild type and a mutant of the histidine kinase 34 gene (hik34), which shows increased thermal tolerance, has been performed in the cyanobacterium Synechocystis sp. PCC6803. In vivo radioactive labellin... Read More about Proteomic analysis of the heat shock response in Synechocystis PCC6803 and a thermally tolerant knockout strain lacking the histidine kinase34 gene.

Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes (2006)
Journal Article
Chaulet, H., Lin, F., Guo, J., Owens, W., Michalicek, J., Kesteven, S., …Graham, R. (2006). Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes. Journal of Molecular and Cellular Cardiology, 40(4), 540-552. https://doi.org/10.1016/j.yjmcc.2006.01.015

We previously reported that transgenic (TG) mice with cardiac-restricted α1A-adrenergic receptor (α1A-AR)-overexpression showed enhanced contractility, but no hypertrophy. Since chronic inotropic enhancement may be deleterious, we investigated if lon... Read More about Sustained augmentation of cardiac 1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes.

A europium complex that selectively stains nucleoli of cells (2006)
Journal Article
Yu, J., Parker, D., Pal, R., Poole, R., & Cann, M. (2006). A europium complex that selectively stains nucleoli of cells. Journal of the American Chemical Society, 128(7), 2294-2299. https://doi.org/10.1021/ja056303g

A europium complex selectively staining the nucleolus of NIH 3T3, HeLa, and HDF cells is reported. This complex possesses not only the advantage of the long lifetime of europium emission (0.3 ms), but also a chromophore that allows excitation at a re... Read More about A europium complex that selectively stains nucleoli of cells.

Divergent roles for IRE1α and PERK in the unfolded protein response (2006)
Journal Article
Schröder, M., & Kaufman, R. (2006). Divergent roles for IRE1α and PERK in the unfolded protein response. Current Molecular Medicine, 6(1), 5-36

The endoplasmic reticulum (ER) provides unique machinery for the folding and posttranslational modification of many secretory and transmembrane proteins in eukaryotic cells. The unfolded protein response (UPR) is a signal transduction network from th... Read More about Divergent roles for IRE1α and PERK in the unfolded protein response.

Rewritable DNA microarrays (2006)
Journal Article
Schofield, W. C. E., McGettrick, J., Bradley, T. J., Badyal, J. P. S., & Przyborski, S. (2006). Rewritable DNA microarrays. Journal of the American Chemical Society, 128(7), 2280-2285. https://doi.org/10.1021/ja056367r

Thiol-terminated single-stranded deoxyribonucleic acids (ssDNA) can be immobilized onto pulsed plasma deposited poly(allylmercaptan) surfaces via disulfide bridge chemistry and are found to readily undergo nucleic acid hybridization. Unlike other met... Read More about Rewritable DNA microarrays.

Library Design, Synthesis And Screening: Pyridine Dicarbonitriles As Potential Prion Disease Therapeutics (2006)
Journal Article
Reddy, T., Mutter, R., Heal, W., Guo, K., Pratt, S., Gillet, V., & Chen, B. (2006). Library Design, Synthesis And Screening: Pyridine Dicarbonitriles As Potential Prion Disease Therapeutics. Journal of Medicinal Chemistry, 49(2), 607-615. https://doi.org/10.1021/jm050610f

Transmissible spongiform encephalopathies (TSEs) or prion diseases are a family of invariably fatal neurodegenerative disorders, and there are no effective therapeutics currently available. In this paper, we report on the design, synthesis, and scree... Read More about Library Design, Synthesis And Screening: Pyridine Dicarbonitriles As Potential Prion Disease Therapeutics.