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Identification and functional expression of a type 2 acyl-CoA:diacylglycerol acyltransferase (DGAT2) in developing castor bean seeds which has high homology to the major triglyceride biosynthetic enzyme of fungi and animals (2006)
Journal Article
Kroon, J. T., Wei, W., Simon, W. J., & Slabas, A. R. (2006). Identification and functional expression of a type 2 acyl-CoA:diacylglycerol acyltransferase (DGAT2) in developing castor bean seeds which has high homology to the major triglyceride biosynthetic enzyme of fungi and animals. Phytochemistry, 67(23), 2541-2549. https://doi.org/10.1016/j.phytochem.2006.09.020

Seed oil from castor bean (Ricinus communis) contains high amounts of hydroxy fatty acid rich triacylglycerols (TAGs) that can serve as raw material for production of bio-based products such as nylon, cosmetics, lubricants, foams, and surfactants. Di... Read More about Identification and functional expression of a type 2 acyl-CoA:diacylglycerol acyltransferase (DGAT2) in developing castor bean seeds which has high homology to the major triglyceride biosynthetic enzyme of fungi and animals.

The POLARIS peptide of Arabidopsis regulates auxin transport and root growth via effects on ethylene signaling (2006)
Journal Article
Chilley, P., Casson, S., Tarkowski, P., Wang, K., Hawkins, N., Hussey, P., …Lindsey, K. (2006). The POLARIS peptide of Arabidopsis regulates auxin transport and root growth via effects on ethylene signaling. The Plant Cell, 18(11), 3058-3072. https://doi.org/10.1105/tpc.106.040790

The rate and plane of cell division and anisotropic cell growth are critical for plant development and are regulated by diverse mechanisms involving several hormone signaling pathways. Little is known about peptide signaling in plant growth; however,... Read More about The POLARIS peptide of Arabidopsis regulates auxin transport and root growth via effects on ethylene signaling.

A physically motivated index of sub-grid scale pattern. (2006)
Journal Article
Jupp, T., & Twiss, S. (2006). A physically motivated index of sub-grid scale pattern. Journal of Geophysical Research, 111(D19), https://doi.org/10.1029/2006jd007343

Earth Observation data on land surface properties such as albedo are typically collected at a pixel resolution of 1 km or less. Global climate models, on the other hand, are constrained by current limits on computing power to run at a grid box resolu... Read More about A physically motivated index of sub-grid scale pattern..

The unfolded protein response (2006)
Journal Article
Schröder, M. (2006). The unfolded protein response. Molecular Biotechnology, 34(2), 279-290

The unfolded protein response (UPR) is a signal transduction network activated by inhibition of protein folding in the endoplasmic reticulum (ER). The UPR coordinates adaptive responses to this stress situation, including induction of ER resident mol... Read More about The unfolded protein response.

Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis (2006)
Journal Article
Estrach, S., Ambler, C., Lo Celso, C., Hozumi, K., & Watt, F. (2006). Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development, 133(22), 4427-4438. https://doi.org/10.1242/dev.02644

The Wnt and Notch signalling pathways regulate hair follicle maintenance, but how they intersect is unknown. We show that Notch signalling is active in the hair follicle pre-cortex, a region of high Wnt activity, where commitment to hair lineages occ... Read More about Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis.

An arsenic metallochaperone for an arsenic detoxification pump (2006)
Journal Article
Lin, Y., Walmsley, A. R., & Rosen, B. P. (2006). An arsenic metallochaperone for an arsenic detoxification pump. Proceedings of the National Academy of Sciences, 103(42), 15617-15622. https://doi.org/10.1073/pnas.0603974103

Environmental arsenic is a world-wide health issue, making it imperative for us to understand mechanisms of metalloid uptake and detoxification. The predominant intracellular form is the highly mephitic arsenite, which is detoxified by removal from c... Read More about An arsenic metallochaperone for an arsenic detoxification pump.

The DM and DM chain cooperate in the oxidation and folding of HLA-DM1 (2006)
Journal Article
van Lith, M., & Benham, A. (2006). The DM and DM chain cooperate in the oxidation and folding of HLA-DM1. The Journal of Immunology, 177(8), 5430-5439

HLA-DM (DM) is a heterodimeric MHC molecule that catalyzes the peptide loading of classical MHC class II molecules in the endosomal/lysosomal compartments of APCs. Although the function of DM is well-established, little is known about how DM and -cha... Read More about The DM and DM chain cooperate in the oxidation and folding of HLA-DM1.

Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents (2006)
Journal Article
Cope, H., Mutter, R., Heal, W., Pascoe, C., Brown, P., Pratt, S., & Chen, B. (2006). Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents. European Journal of Medicinal Chemistry, 41(10), 1124-1143. https://doi.org/10.1016/j.ejmech.2006.05.002

Transmissible spongiform encephalopathies (TSEs) are thought to arise from aggregation of a protease resistant protein denoted PrPSc, which is a misfolded isoform of the normal cellular prion protein PrPC. Using virtual high-throughput screening we h... Read More about Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.