Outputs (68)

Integration of audio-visual information for spatial decisions in children and adults (2015)
Journal Article
Nardini, M., Bales, J., & Mareschal, D. (2016). Integration of audio-visual information for spatial decisions in children and adults. Developmental Science, 19(5), 803-816. https://doi.org/10.1111/desc.12327

In adults, decisions based on multisensory information can be faster and/or more accurate than those relying on a single sense. However, this finding varies significantly across development. Here we studied speeded responding to audio-visual targets,... Read More about Integration of audio-visual information for spatial decisions in children and adults.

Risky visuomotor choices during rapid reaching in childhood (2015)
Journal Article
Dekker, T., & Nardini, M. (2016). Risky visuomotor choices during rapid reaching in childhood. Developmental Science, 19(3), 427-439. https://doi.org/10.1111/desc.12322

Many everyday actions are implicit gambles because imprecisions in our visuomotor systems place probabilities on our success or failure. Choosing optimal action strategies involves weighting the costs and gains of potential outcomes by their correspo... Read More about Risky visuomotor choices during rapid reaching in childhood.

Four-year-olds use a mixture of spatial reference frames (2015)
Journal Article
Negen, J., & Nardini, M. (2015). Four-year-olds use a mixture of spatial reference frames. PLoS ONE, 10(7), https://doi.org/10.1371/journal.pone.0131984

Keeping track of unseen objects is an important spatial skill. In order to do this, people must situate the object in terms of different frames of reference, including body position (egocentric frame of reference), landmarks in the surrounding enviro... Read More about Four-year-olds use a mixture of spatial reference frames.

Flexible integration of visual cues in adolescents with autism spectrum disorder (2015)
Journal Article
Bedford, R., Pellicano, E., Mareschal, D., & Nardini, M. (2016). Flexible integration of visual cues in adolescents with autism spectrum disorder. Autism Research, 9(2), 272-281. https://doi.org/10.1002/aur.1509

Although children with autism spectrum disorder (ASD) show atypical sensory processing, evidence for impaired integration of multisensory information has been mixed. In this study, we took a Bayesian model-based approach to assess within-modality int... Read More about Flexible integration of visual cues in adolescents with autism spectrum disorder.

Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis (2015)
Journal Article
Bainbridge, J., Sundaram, V., Mehat, M., Robbie, S., Barker, S., Ripamonti, C., …Ali, R. (2015). Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis. New England Journal of Medicine, 372(20), 1887-1897. https://doi.org/10.1056/nejmoa1414221

BACKGROUND Mutations in RPE65 cause Leber’s congenital amaurosis, a progressive retinal degenerative disease that severely impairs sight in children. Gene therapy can result in modest improvements in night vision, but knowledge of its efficacy in hum... Read More about Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis.

Automated measurement of resolution acuity in infants using remote eye-tracking (2014)
Journal Article
Jones, P., Kalwarowsky, K., Atkinson, J., Braddick, O., & Nardini, M. (2014). Automated measurement of resolution acuity in infants using remote eye-tracking. Investigative Ophthalmology & Visual Science, 55(12), 8102-8110. https://doi.org/10.1167/iovs.14-15108

Purpose. To validate a novel, automated test of infant resolution acuity based on remote eye-tracking. Methods. Infants aged 2 to 12 months were tested binocularly using a new adaptive computerized test of infant vision using eye tracking (ACTIVE), a... Read More about Automated measurement of resolution acuity in infants using remote eye-tracking.

A prospective longitudinal study of retinal structure and function in achromatopsia (2014)
Journal Article
Aboshiha, J., Dubis, A., Cowing, J., Fahy, R., Sundaram, V., Bainbridge, J., …Michaelides, M. (2014). A prospective longitudinal study of retinal structure and function in achromatopsia. Investigative Ophthalmology & Visual Science, 55(9), 5733-5743. https://doi.org/10.1167/iovs.14-14937

Purpose. To longitudinally characterize retinal structure and function in achromatopsia (ACHM) in preparation for clinical gene therapy trials. Methods. Thirty-eight molecularly confirmed ACHM subjects underwent serial assessments, including spectral... Read More about A prospective longitudinal study of retinal structure and function in achromatopsia.

Crossmodal Integration: A Glimpse into the Development of Sensory Remapping (2014)
Journal Article
Nardini, M., Dekker, T., & Petrini, K. (2014). Crossmodal Integration: A Glimpse into the Development of Sensory Remapping. Current Biology, 24(11), R532-R534. https://doi.org/10.1016/j.cub.2014.04.034

Correctly localising sensory stimuli in space is a formidable challenge for the newborn brain. A new study provides a first glimpse into how human brain mechanisms for sensory remapping develop in the first year of life.

When vision is not an option: children's integration of auditory and haptic information is suboptimal (2014)
Journal Article
Petrini, K., Remark, A., Smith, L., & Nardini, M. (2014). When vision is not an option: children's integration of auditory and haptic information is suboptimal. Developmental Science, 17(3), 376-387. https://doi.org/10.1111/desc.12127

When visual information is available, human adults, but not children, have been shown to reduce sensory uncertainty by taking a weighted average of sensory cues. In the absence of reliable visual information (e.g. extremely dark environment, visual d... Read More about When vision is not an option: children's integration of auditory and haptic information is suboptimal.

Weighted cue integration in the rodent head direction system (2014)
Journal Article
Knight, R., Piette, C., Page, H., Walters, D., Marozzi, E., Nardini, M., …Jeffery, K. (2014). Weighted cue integration in the rodent head direction system. Philosophical Transactions of the Royal Society B: Biological Sciences, 369(1635), Article 20120512. https://doi.org/10.1098/rstb.2012.0512

How the brain combines information from different sensory modalities and of differing reliability is an important and still-unanswered question. Using the head direction (HD) system as a model, we explored the resolution of conflicts between landmark... Read More about Weighted cue integration in the rodent head direction system.