Research Highlights
(2006)
Journal Article
Denny, P. (2006). Research Highlights. Nature Reviews Drug Discovery, 5(9), https://doi.org/10.1038/nrd2143
The protozoan inositol phosphorylceramide synthase: A novel drug target that defines a new class of sphingolipid synthase (2006)
Journal Article
Denny, P., Shams-Eldin, H., Price, H., Smith, D., & Schwarz, R. (2006). The protozoan inositol phosphorylceramide synthase: A novel drug target that defines a new class of sphingolipid synthase. Journal of Biological Chemistry, 281(38), 28200-28209. https://doi.org/10.1074/jbc.m600796200Sphingolipids are ubiquitous and essential components of eukaryotic membranes, particularly the plasma membrane. The biosynthetic pathway for the formation of these lipid species is conserved up to the formation of sphinganine. However, a divergence... Read More about The protozoan inositol phosphorylceramide synthase: A novel drug target that defines a new class of sphingolipid synthase.