The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system (2002)
Journal Article
Morgan, G., Hall, B., Denny, P., Field, M., & Carrington, M. (2002). The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system. Trends in Parasitology, 18(12), 540-546. https://doi.org/10.1016/s1471-4922%2802%2902392-9

Endocytic systems within eukaryotic cells are a diverse set of intracellular transport pathways responsible for uptake, recycling, interaction with the exocytic system and degradation of molecules. Each of these pathways requires the interaction of d... Read More about The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system.

The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences (2002)
Journal Article
Morgan, G., Hall, B., Denny, P., Carrington, M., & Field, M. (2002). The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences. Trends in Parasitology, 18(11), 491-496. https://doi.org/10.1016/s1471-4922%2802%2902391-7

The endocytic system of kinetoplastid parasites is a highly polarized membrane network focused on the flagellar pocket localized at one end of the cell. When first characterized, the endosomal network was envisioned as a simple system for uptake of e... Read More about The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences.

Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite (2002)
Journal Article
Denny, P., Lewis, S., Tempero, J., Goulding, D., Ivens, A., Field, M., & Smith, D. (2002). Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite. Molecular and Biochemical Parasitology, 123(2), 105-113. https://doi.org/10.1016/s0166-6851%2802%2900133-0

Leishmania species are intracellular parasites that inhabit a parasitophorous vacuole (PV) within host macrophages and engage with the host endo-membrane network to avoid clearance from the cell. Intracellular Leishmania amastigotes exhibit a high de... Read More about Leishmania RAB7: characterisation of terminal endocytic stages in an intracellular parasite.