Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B (2021)
Journal Article
Pakosz, Z., Lin, T., Michalczyk, E., Nagano, S., & Heddle, J. G. (2021). Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B. Antimicrobial Agents and Chemotherapy, 65(10), https://doi.org/10.1128/aac.00267-21

Malaria persists as a major health problem due to the spread of drug resistance and the lack of effective vaccines. DNA gyrase is a well-validated and extremely effective therapeutic target in bacteria, and it is also known to be present in the apico... Read More about Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B.

Pseudouridines in RNAs: switching atoms means shifting paradigms (2021)
Journal Article
Lin, T., Mehta, R., & Glatt, S. (2021). Pseudouridines in RNAs: switching atoms means shifting paradigms. FEBS Letters, 595(18), 2310-2322. https://doi.org/10.1002/1873-3468.14188

The structure, stability, and function of various coding and noncoding RNAs are influenced by chemical modifications. Pseudouridine (Ψ) is one of the most abundant post-transcriptional RNA base modifications and has been detected at individual positi... Read More about Pseudouridines in RNAs: switching atoms means shifting paradigms.