Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1 H NMR spectroscopy (2021)
Journal Article
Wylot, M., Whittaker, D. T., Wren, S. A., Bothwell, J. H., Hughes, L., & Griffin, J. L. (2021). Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1 H NMR spectroscopy. NMR in Biomedicine, 34(3), Article e4456. https://doi.org/10.1002/nbm.4456

Apoptosis maintains an equilibrium between cell proliferation and cell death. Many diseases, including cancer, develop because of defects in apoptosis. A known metabolic marker of apoptosis is a notable increase in 1H NMR‐observable resonances associ... Read More about Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1 H NMR spectroscopy.

Insights into the Evolution of Multicellularity from the Sea Lettuce Genome (2018)
Journal Article
De Clerck, O., Kao, S., Bogaert, K. A., Blomme, J., Foflonker, F., Kwantes, M., …Bothwell, J. H. (2018). Insights into the Evolution of Multicellularity from the Sea Lettuce Genome. Current Biology, 28(18), 2921-2933.e5. https://doi.org/10.1016/j.cub.2018.08.015

We report here the 98.5 Mbp haploid genome (12,924 protein coding genes) of Ulva mutabilis, a ubiquitous and iconic representative of the Ulvophyceae or green seaweeds. Ulva’s rapid and abundant growth makes it a key contributor to coastal biogeochem... Read More about Insights into the Evolution of Multicellularity from the Sea Lettuce Genome.

Agrobacterium-mediated gene delivery and transient expression in the red macroalga Chondrus crispus (2018)
Journal Article
Ramessur, A. D., Bothwell, J. H., Maggs, C. A., Gan, S. Y., & Phang, S. M. (2018). Agrobacterium-mediated gene delivery and transient expression in the red macroalga Chondrus crispus. Botanica Marina, 61(5), 499-510. https://doi.org/10.1515/bot-2018-0028

Molecular resources and transgenic studies in red algae are lagging behind those for green algae. The Agrobacterium-mediated gene-transfer method routinely used in plant transformation has not been fully utilised in the red algae, which, as an import... Read More about Agrobacterium-mediated gene delivery and transient expression in the red macroalga Chondrus crispus.

The effects of spatial scale and isoscape on consumer isotopic niche width (2017)
Journal Article
Reddin, C. J., Bothwell, J. H., O'Connor, N. E., & Harrod, C. (2018). The effects of spatial scale and isoscape on consumer isotopic niche width. Functional Ecology, 32(4), 904-915. https://doi.org/10.1111/1365-2435.13026

An integrated process for the extraction of fuel and chemicals from marine macroalgal biomass (2016)
Journal Article
Trivedi, N., Baghel, R. S., Bothwell, J., Gupta, V., Reddy, C., Lali, A. M., & Jha, B. (2016). An integrated process for the extraction of fuel and chemicals from marine macroalgal biomass. Scientific Reports, 6(1), Article 30728. https://doi.org/10.1038/srep30728

We describe an integrated process that can be applied to biomass of the green seaweed, Ulva fasciata, to allow the sequential recovery of four economically important fractions; mineral rich liquid extract (MRLE), lipid, ulvan, and cellulose. The main... Read More about An integrated process for the extraction of fuel and chemicals from marine macroalgal biomass.

Between-taxon matching of common and rare species richness patterns (2015)
Journal Article
Reddin, C., Bothwell, J., & Lennon, J. (2015). Between-taxon matching of common and rare species richness patterns. Global Ecology and Biogeography, 24(12), 1476-1486. https://doi.org/10.1111/geb.12372

Coastal Upwelling Drives Intertidal Assemblage Structure and Trophic Ecology (2015)
Journal Article
Reddin, C., Docmac, F., O’Connor, N., Bothwell, J., & Harrod, C. (2015). Coastal Upwelling Drives Intertidal Assemblage Structure and Trophic Ecology. PLoS ONE, 10(7), Article e0130789. https://doi.org/10.1371/journal.pone.0130789

Similar environmental driving forces can produce similarity among geographically distant ecosystems. Coastal oceanic upwelling, for example, has been associated with elevated biomass and abundance patterns of certain functional groups, e.g., corticat... Read More about Coastal Upwelling Drives Intertidal Assemblage Structure and Trophic Ecology.

The green seaweed Ulva: a model system to study morphogenesis (2015)
Journal Article
Wichard, T., Charrier, B., Mineur, B., Bothwell, J., De Clerck, O., & Coates, J. (2015). The green seaweed Ulva: a model system to study morphogenesis. Frontiers in Plant Science, 6, Article 72. https://doi.org/10.3389/fpls.2015.00072

Green macroalgae, mostly represented by the Ulvophyceae, the main multicellular branch of the Chlorophyceae, constitute important primary producers of marine and brackish coastal ecosystems. Ulva or sea lettuce species are some of the most abundant r... Read More about The green seaweed Ulva: a model system to study morphogenesis.

A haploid system of sex determination in the brown alga Ectocarpus sp. (2014)
Journal Article
Ahmed, S., Cock, J., Pessia, E., Luthringer, R., Cormier, A., Robuchon, M., …Coelho, S. (2014). A haploid system of sex determination in the brown alga Ectocarpus sp. Current Biology, 24(17), 1945-1957. https://doi.org/10.1016/j.cub.2014.07.042

Genome structure and metabolic features in the red seaweed Chondrus crispus shed light on evolution in the Archaeplastida (2013)
Journal Article
Collén, J., Porcel, B., Carré, W., Ball, S. G., Chaparro, C., Tonon, T., …Boyen, C. (2013). Genome structure and metabolic features in the red seaweed Chondrus crispus shed light on evolution in the Archaeplastida. Proceedings of the National Academy of Sciences, 110(13), 5247-5252. https://doi.org/10.1073/pnas.1221259110

NOX or not? Evidence for algal NADPH oxidases (2011)
Journal Article
Anderson, A., Bothwell, J. H., Laohavisit, A., Smith, A. G., & Davies, J. M. (2011). NOX or not? Evidence for algal NADPH oxidases. Trends in Plant Science, 16(11), 579-581. https://doi.org/10.1016/j.tplants.2011.09.003

An introduction to biological nuclear magnetic resonance spectroscopy (2011)
Journal Article
Bothwell, J. H., & Griffin, J. L. (2011). An introduction to biological nuclear magnetic resonance spectroscopy. Biological Reviews, 86(2), 493-510. https://doi.org/10.1111/j.1469-185x.2010.00157.x

Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful analytical techniques available to biology. This review is an introduction to the potential of this method and is aimed at readers who have little or no experience in acquiring... Read More about An introduction to biological nuclear magnetic resonance spectroscopy.

The Ectocarpus genome and the independent evolution of multicellularity in brown algae (2010)
Journal Article
Cock, J. M., Sterck, L., Rouze, P., Scornet, D., Allen, A. E., Amoutzias, G., …Wincker, P. (2010). The Ectocarpus genome and the independent evolution of multicellularity in brown algae. Nature, 465(7298), 617-621. https://doi.org/10.1038/nature09016

Role of endoreduplication and apomeiosis during parthenogenetic reproduction in the model brown alga Ectocarpus siliculosus. (2010)
Journal Article
Bothwell, J., Marie, D., Peters, A., Cock, J., & Coelho, S. (2010). Role of endoreduplication and apomeiosis during parthenogenetic reproduction in the model brown alga Ectocarpus siliculosus. New Phytologist, 188(1), 111-121. https://doi.org/10.1111/j.1469-8137.2010.03357.x

Two voltage-dependent calcium channels co-exist in the apical plasma membrane of Arabidopsis thaliana root hairs. (2008)
Journal Article
Miedema, H., Demidchik, V., Véry, A., Bothwell, J., Brownlee, C., & Davies, J. (2008). root hairs. New Phytologist, 179(2), https://doi.org/10.1111/j.1469-8137.2008.02465.x

Ca2+ signals co-ordinate zygotic polarization and cell cycle progression in the brown alga, Fucus serratus. (2008)
Journal Article
Bothwell, J., Kisielewska, J., Genner, M., McAinsh, M., & Brownlee, C. (2008). Ca2+ signals co-ordinate zygotic polarization and cell cycle progression in the brown alga, Fucus serratus. Development, 135(12), 2173-2181. https://doi.org/10.1242/dev.017558

A tip-high, Ca2+-interdependent, reactive oxygen species gradient is associated with polarized growth in Fucus serratus zygotes. (2008)
Journal Article
Coelho, S., Brownlee, C., & Bothwell, J. (2008). oxygen species gradient is associated with polarized growth in Fucus serratus zygotes. Planta, 227(5), 1037-1046. https://doi.org/10.1007/s00425-007-0678-9

The long past of systems biology (2006)
Journal Article
Bothwell, J. (2006). The long past of systems biology. New Phytologist, 170(1), 6-10. https://doi.org/10.1111/j.1469-8137.2006.01676.x

Biolistic delivery of Ca2+ dyes into plant and algal cells (2006)
Journal Article
Bothwell, J., Brownlee, C., Hetherington, A., Ng, C., Wheeler, G., & McAinsh, M. (2006). Biolistic delivery of Ca2+ dyes into plant and algal cells. The Plant Journal, 46(2), 327-335. https://doi.org/10.1111/j.1365-313x.2006.02687.x

The evolution of Ca2+ signalling in photosynthetic eukaryotes (2005)
Journal Article
Bothwell, J., & Ng, C. (2005). The evolution of Ca2+ signalling in photosynthetic eukaryotes. New Phytologist, 166(1), 21-38. https://doi.org/10.1111/j.1469-8137.2004.01312.x