Anion-switchable supramolecular gels for controlling pharmaceutical crystal growth (2010)
Journal Article
Foster, J., Piepenbrock, M., Lloyd, G., Clarke, N., Howard, J., & Steed, J. (2010). Anion-switchable supramolecular gels for controlling pharmaceutical crystal growth. Nature Chemistry, 2(12), 1037-1043. https://doi.org/10.1038/nchem.859

We describe the use of low-molecular-weight supramolecular gels as media for the growth of molecular crystals. Growth of a range of crystals of organic compounds, including pharmaceuticals, was achieved in bis(urea) gels. Low-molecular-weight supramo... Read More about Anion-switchable supramolecular gels for controlling pharmaceutical crystal growth.

Designing Co-Crystals of Pharmaceutically Relevant Compounds That Crystallize with Z’ > 1 (2009)
Journal Article
Anderson, K., Probert, M., Whiteley, C., Rowland, A., Goeta, A., & Steed, J. (2009). Designing Co-Crystals of Pharmaceutically Relevant Compounds That Crystallize with Z’ > 1. Crystal Growth and Design, 9(2), 1082-1087. https://doi.org/10.1021/cg8009089

Gelation is crucially dependent on functional group orientation and may be tuned by anion binding (2008)
Journal Article
Piepenbrock, M., Lloyd, G., Clarke, N., & Steed, J. (2008). Gelation is crucially dependent on functional group orientation and may be tuned by anion binding. Chemical Communications, 2644-2646. https://doi.org/10.1039/b804259d

Structure Calculation of an Elastic Hydrogel from Sonication of Rigid Small Molecule Components (2008)
Journal Article
Anderson, K., Day, G., Paterson, M., Byrne, P., Clarke, N., & Steed, J. (2008). Structure Calculation of an Elastic Hydrogel from Sonication of Rigid Small Molecule Components. Angewandte Chemie International Edition, 47(6), 1058-1062. https://doi.org/10.1002/anie.200703785

Induced Fit Interanion Discrimination by Binding-Induced Excimer Formation (2008)
Journal Article
Filby, M. H., Dickson, S. J., Zaccheroni, N., Prodi, L., Bonacchi, S., Montalti, M., …Steed, J. (2008). Induced Fit Interanion Discrimination by Binding-Induced Excimer Formation. Journal of the American Chemical Society, 130(12), 4105-4113. https://doi.org/10.1021/ja711012d

Unusual variations in the incidence of Z ' > 1 in oxo-anion structures (2006)
Journal Article
Anderson, K., Goeta, A., Hancock, K., & Steed, J. (2006). Unusual variations in the incidence of Z ' > 1 in oxo-anion structures. Chemical Communications, 2006(20), 2138-2140. https://doi.org/10.1039/b602492k

A series of Cambridge Structural Database studies show that ionic species generally form low Z′ structures, even in those cases where charge assisted hydrogen bonding is a key feature, e.g. oxo-anion complexes. By introducing a competing π–π stacking... Read More about Unusual variations in the incidence of Z ' > 1 in oxo-anion structures.

Anion-binding mode in a sulfanylphenyl urea complex : solid state symmetry breaking and solution chelation. (2006)
Journal Article
Russell, J., Parker, A., Radosavljevic-Evans, I., Howard, J., & Steed, J. (2006). Anion-binding mode in a sulfanylphenyl urea complex : solid state symmetry breaking and solution chelation. CrystEngComm, 8(2), 119-122. https://doi.org/10.1039/b516962c

An anion-bridged, hydrogen bonded coordination polymer apparently adapts its symmetry to form a Z′ = 1 or 2 structure according to the hydrogen bonding demands of the anion, and in solution there is evidence for a discrete anion-binding coordination... Read More about Anion-binding mode in a sulfanylphenyl urea complex : solid state symmetry breaking and solution chelation..

A modular approach to organic, coordination complex and polymer based podand hosts for anions. (2006)
Journal Article
Filby, M., & Steed, J. (2006). A modular approach to organic, coordination complex and polymer based podand hosts for anions. Coordination Chemistry Reviews, 250(23-24), 3200-3218. https://doi.org/10.1016/j.ccr.2006.06.004

A range of novel host molecules with various degrees of preorganisation for the supramolecular complexation of anionic guest species are analysed within the context of other recent advances in the field. A modular approach to the design of cationic p... Read More about A modular approach to organic, coordination complex and polymer based podand hosts for anions..

Simultaneous anion and cation binding by a simple polymer-bound ureidopyridyl ligand. (2006)
Journal Article
Russell, J., Parker, A., Radosavljevie-Evans, I., Howard, J., & Steed, J. (2006). Simultaneous anion and cation binding by a simple polymer-bound ureidopyridyl ligand. Chemical Communications, 2006(3), 269-271. https://doi.org/10.1039/b513820e

A polymer-supported ligand capable of simultaneous anion and cation binding is reported along with X-ray crystallographic data showing potential binding modes.

When Z '=2 is better than Z '=1-supramolecular centrosymmetric hydrogen-bonded dimers in chiral systems (2006)
Journal Article
Anderson, K., Afarinkia, K., Yu, H., Goeta, A., & Steed, J. (2006). When Z '=2 is better than Z '=1-supramolecular centrosymmetric hydrogen-bonded dimers in chiral systems. Crystal Growth and Design, 6(9), 2109-2113. https://doi.org/10.1021/cg0603265

High Z‘ structures can be engineered by combining a molecule with one (or more) resolved chiral center(s) with a strongly directional supramolecular synthon with a preference for centrosymmetry because, in order to preserve the dimer motif, one or mo... Read More about When Z '=2 is better than Z '=1-supramolecular centrosymmetric hydrogen-bonded dimers in chiral systems.

Crystal engineering with ethynylbenzenes Part 2. Structures of 4-trimethylsilylethynyl-N,N-dimethylaniline, and 4-ethynyl-N,N-dimethylaniline with Z '=12 and a single-crystal to single-crystal phase transition at 122.5 +/- 2 K (2006)
Journal Article
Batsanov, A., Collings, J., Ward, R., Goeta, A., Porres, L., Beeby, A., …Marder, T. (2006). Crystal engineering with ethynylbenzenes Part 2. Structures of 4-trimethylsilylethynyl-N,N-dimethylaniline, and 4-ethynyl-N,N-dimethylaniline with Z '=12 and a single-crystal to single-crystal phase transition at 122.5 +/- 2 K. CrystEngComm, 8, 622-628. https://doi.org/10.1039/b606327f

The crystal and molecular structures of 4-ethynyl-N,N-dimethylaniline (1), and 4-(trimethylsilylethynyl)-N,N-dimethylaniline (2), have been obtained from X-ray diffraction data. Crystals of 1 exhibit a phase transition at 122.5 ± 2 K. Both polymorphs... Read More about Crystal engineering with ethynylbenzenes Part 2. Structures of 4-trimethylsilylethynyl-N,N-dimethylaniline, and 4-ethynyl-N,N-dimethylaniline with Z '=12 and a single-crystal to single-crystal phase transition at 122.5 +/- 2 K.

Helical or polar guest-dependent Z‘ = 1.5 or Z‘ = 2 forms of a sterically hindered bis(urea) clathrate. (2006)
Journal Article
Todd, A., Anderson, K., Byrne, P., Goeta, A., & Steed, J. (2006). Helical or polar guest-dependent Z‘ = 1.5 or Z‘ = 2 forms of a sterically hindered bis(urea) clathrate. Crystal Growth and Design, 6(8), 1750-1752. https://doi.org/10.1021/cg060318o

A sterically hindered bis(pyridylurea) species forms clathrates with water, methanol, and ethanol, all exhibiting unusual polar structures with Z‘ > 1. This crystal packing is due to the hindered geometry about the urea oxygen acceptor atoms.

Anion binding inhibition of the formation of a helical organogel (2006)
Journal Article
Stanley, C., Clarke, N., Anderson, K., Elder, J., Lenthall, J., & Steed, J. (2006). Anion binding inhibition of the formation of a helical organogel. Chemical Communications, 3199-3201. https://doi.org/10.1039/b606373j

A chiral tris(urea) organogelator gels dmso–water and methanol–water mixtures at low weight percent. The formation of the helical gel fibres is partially inhibited by addition of chloride, which is bound by the gelator, resulting in fully crystalline... Read More about Anion binding inhibition of the formation of a helical organogel.

On the protonation of a macrobicyclic cage: an inert tribenzylamine fragment and three robust aminophosphonium units. (2006)
Journal Article
Alajarín, M., López-Leonardo, C., Berná, J., & Steed, J. (2006). On the protonation of a macrobicyclic cage: an inert tribenzylamine fragment and three robust aminophosphonium units. Tetrahedron Letters, 47(30), 5405-5408. https://doi.org/10.1016/j.tetlet.2006.05.112

The protonation of a macrobicyclic cage with four intracyclic nitrogen atoms (one included into a tribenzylamine fragment and the other three into iminophosphorane units) led to tris(aminophosphonium) cations. In the salts, the three anions are situa... Read More about On the protonation of a macrobicyclic cage: an inert tribenzylamine fragment and three robust aminophosphonium units..

A modular approach to anion binding podands: adaptability in design and synthesis leads to adaptability in properties (2006)
Journal Article
Steed, J. (2006). A modular approach to anion binding podands: adaptability in design and synthesis leads to adaptability in properties. Chemical Communications, 2637-2649. https://doi.org/10.1039/b601511e

Progress in the development of a modular approach towards flexible anion-binding and sensing systems is reviewed within the context of related developments in conformationally flexible anion- and salt-binding hosts. The transferability of concepts an... Read More about A modular approach to anion binding podands: adaptability in design and synthesis leads to adaptability in properties.

Pyridinium CH center dot center dot center dot anion and pi-stacking interactions in modular tripodal anion binding hosts: ATP binding and solid-state chiral induction (2006)
Journal Article
Belcher, W., Fabre, M., Farhan, T., & Steed, J. (2006). Pyridinium CH center dot center dot center dot anion and pi-stacking interactions in modular tripodal anion binding hosts: ATP binding and solid-state chiral induction. Organic and Biomolecular Chemistry, 4(5), 781-786. https://doi.org/10.1039/b516027h

The preparation of two new tripodal ‘pinwheel’ type anion hosts based on a triethylbenzene core and bipyridinium or ethylnicotinium arms is reported. The new materials bind anions via CH⋯anion interactions. Complexes with Br− and PF6− have been chara... Read More about Pyridinium CH center dot center dot center dot anion and pi-stacking interactions in modular tripodal anion binding hosts: ATP binding and solid-state chiral induction.

A conformationally flexible, urea-based tripodal anion receptor: Solid-state, solution, and theoretical studies (2006)
Journal Article
Turner, D., Paterson, M., & Steed, J. (2006). A conformationally flexible, urea-based tripodal anion receptor: Solid-state, solution, and theoretical studies. Journal of Organic Chemistry, 71(4), 1598-1608. https://doi.org/10.1021/jo052339f

Tripodal tris(urea) cationic receptors 1 and 2 containing p-tolyl or octyl substituents, respectively, have been synthesized, and their association behavior with anionic guests has been studied via a variety of methods. The receptors are based around... Read More about A conformationally flexible, urea-based tripodal anion receptor: Solid-state, solution, and theoretical studies.

Anion binding by Ag(I) complexes of urea-substituted pyridyl ligands (2005)
Journal Article
Turner, D., Smith, B., Spencer, E., Goeta, A., Evans, I., Tocher, D., …Steed, J. (2005). Anion binding by Ag(I) complexes of urea-substituted pyridyl ligands. New Journal of Chemistry, 29(1), 90-98

A series of Ag(I) complexes of ureidopyridyl ligands 1 and 2 have been prepared from oxo-anion salts. In all cases the new materials contain the AgL2+ cation interacting with oxo-anions via the urea moiety. The complexes containing the para ligand 2:... Read More about Anion binding by Ag(I) complexes of urea-substituted pyridyl ligands.

Alkene-arene meta photocycloadditions with a four-carbon-atom tether: Efficient approach toward the polycyclic ring systems of aphidicolin and stemodinone (2005)
Journal Article
Boyd, J., Greaves, N., Kettle, J., Russell, A., & Steed, J. (2005). Alkene-arene meta photocycloadditions with a four-carbon-atom tether: Efficient approach toward the polycyclic ring systems of aphidicolin and stemodinone. Angewandte Chemie International Edition, 44(6), 944-946

Influence of hydrogen bonding on coordination polymer assembly (2005)
Journal Article
Applegarth, L., Goeta, A., & Steed, J. (2005). Influence of hydrogen bonding on coordination polymer assembly. Chemical Communications, 2405-2406

An extended dipyridyl ligand (L-1) capable of hydrogen bonding with guest species via urea functionalities has been designed and synthesised. Assembly of a silver(I) coordination polymer of L-1 is dependent on the nature of the hydrogen bond acceptor... Read More about Influence of hydrogen bonding on coordination polymer assembly.