Skip to main content

Research Repository

Advanced Search

Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation (2011)
Journal Article
Pekovic, V., Gibbs-Seymour, I., Markiewicz, E., Alzoghaibi, F., Benham, A., Edwards, R., …Hutchison, C. (2011). Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation. Aging Cell, 10(6), 1067-1079. https://doi.org/10.1111/j.1474-9726.2011.00750.x

Pre-lamin A and progerin have been implicated in normal aging, and the pathogenesis of age-related degenerative diseases is termed ‘laminopathies’. Here, we show that mature lamin A has an essential role in cellular fitness and that oxidative damage... Read More about Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation.

Maximisation of Minors' Capacity (2011)
Journal Article
Cave, E. (2011). Maximisation of Minors' Capacity. Child and family law quarterly, 23(4), 431-449

Section 3(2) of the Mental Capacity Act 2005 requires doctors to take practical steps to help a person with impaired capacity to make a competent medical decision. This legal duty does not extend to minors under the age of 16. They must prove their c... Read More about Maximisation of Minors' Capacity.

“They're Made in Factories and Not by Witches on the Allotment”: A Qualitative Study of Midlife Women in the United Kingdom, Exploring Their Approaches to Complementary and Alternative Medicines. (2011)
Journal Article
Lindenmeyer, A., Jamie, K., Griffiths, F., & LéGaré, F. (2011). “They're Made in Factories and Not by Witches on the Allotment”: A Qualitative Study of Midlife Women in the United Kingdom, Exploring Their Approaches to Complementary and Alternative Medicines. Health Care for Women International, 32(12), 1046-1067. https://doi.org/10.1080/07399332.2011.603864

This article explores midlife women's experiences and approaches related to complementary and alternative therapies (CAMS). Ninety-six midlife women were asked about their use of CAMs as part of their overall approach to midlife health. Qualitative t... Read More about “They're Made in Factories and Not by Witches on the Allotment”: A Qualitative Study of Midlife Women in the United Kingdom, Exploring Their Approaches to Complementary and Alternative Medicines..

The Principle of Generic Consistency as the Supreme Principle of Human Rights (2011)
Journal Article
Beyleveld, D. (2011). The Principle of Generic Consistency as the Supreme Principle of Human Rights. Human Rights Review, 13(1), 1-18. https://doi.org/10.1007/s12142-011-0210-2

Alan Gewirth’s claim that agents contradict that they are agents if they do not accept that the principle of generic consistency (PGC) is the supreme principle of practical rationality has been greeted with widespread scepticism. The aim of this arti... Read More about The Principle of Generic Consistency as the Supreme Principle of Human Rights.

Clinical Governance (2011)
Journal Article
Jaggs-Fowler, R. (2011). Clinical Governance. InnovAiT: Education and inspiration for general practice, 4(10), 592-595. https://doi.org/10.1093/innovait/inr069

Clinical governance is central to the modern day practice of medicine. However, despite its importance, it remains a concept that is commonly cited but rarely explained. This article looks at the origins of the term ‘clinical governance’, attempts to... Read More about Clinical Governance.

Beginning to teach chemistry: How personal and academic characteristics of pre-service science teachers compare with their understandings of basic chemical ideas (2011)
Journal Article
Kind, V., & Kind, P. (2011). Beginning to teach chemistry: How personal and academic characteristics of pre-service science teachers compare with their understandings of basic chemical ideas. International Journal of Science Education, 33(15), 2123-2158. https://doi.org/10.1080/09500693.2010.542498

Around 150 pre-service science teachers (PSTs) participated in a study comparing academic and personal characteristics with their misconceptions about basic chemical ideas taught to 11–16-year-olds, such as particle theory, change of state, conservat... Read More about Beginning to teach chemistry: How personal and academic characteristics of pre-service science teachers compare with their understandings of basic chemical ideas.

Directed donation and ownership of human organs (2011)
Journal Article
Pattinson, S. D. (2011). Directed donation and ownership of human organs. Legal Studies, 31(3), 392-410. https://doi.org/10.1111/j.1748-121x.2011.00195.x

This paper explores the issue of donation of organs from deceased donors for transplantation into a specified recipient. It argues that proper account should be taken of the principles underlying the Human Tissue Act 2004, which grant the donor a for... Read More about Directed donation and ownership of human organs.

Redress in the NHS (2011)
Journal Article
Cave, E. (2011). Redress in the NHS. Tottel's journal of professional negligence, 27(3), 138-157

Theorising the ‘human subject’ in biomedical research: International clinical trials and bioethics discourses in contemporary Sri Lanka. (2011)
Journal Article
Sariola, S., & Simpson, B. (2011). Theorising the ‘human subject’ in biomedical research: International clinical trials and bioethics discourses in contemporary Sri Lanka. Social Science & Medicine, 73(4), 515-521. https://doi.org/10.1016/j.socscimed.2010.11.024

The global spread of clinical trials activity is accompanied by a parallel growth in research governance and human subject protection. In this paper we analyse how dominant ideas of the ‘human subject’ in clinical trials are played out in countries t... Read More about Theorising the ‘human subject’ in biomedical research: International clinical trials and bioethics discourses in contemporary Sri Lanka..

Medical Law and Ethics (2011)
Book
Pattinson, S. D. (2011). Medical Law and Ethics. (3rd ed.). Sweet and Maxwell

This interdisciplinary text seeks to advance understanding of medical law by application of a moral and contextual framework initially outlined in the first chapter and, in the process, seeks to demonstrate the need for a moral epistemology of the ty... Read More about Medical Law and Ethics.

A Flow Cytometry-Based Screen of Nuclear Envelope Transmembrane Proteins Identifies NET4/Tmem53 as Involved in Stress-Dependent Cell Cycle Withdrawal (2011)
Journal Article
Korfali, N., Srsen, V., Waterfall, M., Batrakou, D. G., Pekovic, V., Hutchison, C. J., & Schirmer, E. C. (2011). A Flow Cytometry-Based Screen of Nuclear Envelope Transmembrane Proteins Identifies NET4/Tmem53 as Involved in Stress-Dependent Cell Cycle Withdrawal. PLoS ONE, 6(4), Article e18762. https://doi.org/10.1371/journal.pone.0018762

Disruption of cell cycle regulation is one mechanism proposed for how nuclear envelope protein mutation can cause disease. Thus far only a few nuclear envelope proteins have been tested/found to affect cell cycle progression: to identify others, 39 n... Read More about A Flow Cytometry-Based Screen of Nuclear Envelope Transmembrane Proteins Identifies NET4/Tmem53 as Involved in Stress-Dependent Cell Cycle Withdrawal.

Policing, Profiling and Discrimination Law: US and European Approaches Compared (2011)
Journal Article
Phillipson, G., & Baker, A. (2011). Policing, Profiling and Discrimination Law: US and European Approaches Compared. Journal of Global Ethics, 7(1), 105-124. https://doi.org/10.1080/17449626.2011.556142

Counter-terrorism officials in the USA and the UK responded to the events of 11 September 2001 and 7 July 2005 with an increasing resort to the use of ‘intelligence-led policing’ methods such as racial and religious profiling. Reliance on intelligenc... Read More about Policing, Profiling and Discrimination Law: US and European Approaches Compared.

The State of Global Health in a Radically Unequal World: Patterns and Prospects (2011)
Book Chapter
Labonté, R., & Schrecker, T. (2011). The State of Global Health in a Radically Unequal World: Patterns and Prospects. In S. Benatar, & G. Brock (Eds.), Global health and global health ethics (24-36). Cambridge University Press

“If living were a thing that money could buy” Imagine for a moment a series of disasters that killed almost 1400 women every day for a year: the equivalent of four or five daily crashes of crowded long-distance airliners. There is little question tha... Read More about The State of Global Health in a Radically Unequal World: Patterns and Prospects.

Blood Rhetorics: Donor campaigns and their publics in contemporary Sri Lanka (2011)
Journal Article
Simpson, B. (2011). Blood Rhetorics: Donor campaigns and their publics in contemporary Sri Lanka. Ethnos, 76(2), 254-275. https://doi.org/10.1080/00141844.2010.546868

In this article, I focus on an aspect of voluntary blood donation that has received relatively little attention, namely the spaces – public, moral and political – that connnect individual donors with the recipients of blood. More specifically I focus... Read More about Blood Rhetorics: Donor campaigns and their publics in contemporary Sri Lanka.